Structural basis of the negative allosteric modulation of 5-BDBD at human P2X4 receptors S Bidula, IB Nadzirin, M Cominetti, H Hickey, SA Cullum, M Searcey, ... Molecular pharmacology 101 (1), 33-44, 2022 | 16 | 2022 |
Combined docking and machine learning identify key molecular determinants of ligand pharmacological activity on β2 adrenoceptor M Jiménez‐Rosés, BA Morgan, M Jimenez Sigstad, TDZ Tran, ... Pharmacology Research & Perspectives 10 (5), e00994, 2022 | 13* | 2022 |
Kinetic analysis of endogenous β2‐adrenoceptor‐mediated cAMP GloSensor™ responses in HEK293 cells SA Cullum, DB Veprintsev, SJ Hill British Journal of Pharmacology 180 (10), 1304-1315, 2023 | 8 | 2023 |
Mechano-sensitivity of β2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists SA Cullum, S Platt, N Dale, OC Isaac, ES Wragg, M Soave, DB Veprintsev, ... Communications Biology 7 (1), 417, 2024 | 2 | 2024 |
ThermoBRET: A Ligand‐Engagement Nanoscale Thermostability Assay Applied to GPCRs BL Hoare, DN Tippett, A Kaur, SA Cullum, T Miljuš, EJ Koers, ... ChemBioChem 25 (2), e202300459, 2024 | 1* | 2024 |
Investigations into β2-adrenoceptor pharmacology: kinetic analysis, mechanotransduction and allosteric modulation SA Cullum University of Nottingham, 0 | | |