دنبال کردن
Yixuan J. Hou
Yixuan J. Hou
Moderna Therapeutics
ایمیل تأیید شده در modernatx.com
عنوان
نقل شده توسط
نقل شده توسط
سال
SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract
YJ Hou, K Okuda, CE Edwards, DR Martinez, T Asakura, KH Dinnon, ...
Cell 182 (2), 429-446. e14, 2020
16162020
SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo
YJ Hou, S Chiba, P Halfmann, C Ehre, M Kuroda, KH Dinnon III, SR Leist, ...
Science 370 (6523), 1464-1468, 2020
10182020
The receptor-binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients
L Premkumar, B Segovia-Chumbez, R Jadi, DR Martinez, R Raut, ...
Science immunology 5 (48), eabc8413, 2020
9602020
A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures
KH Dinnon III, SR Leist, A Schäfer, CE Edwards, DR Martinez, ...
Nature 586 (7830), 560-566, 2020
7322020
A mouse-adapted SARS-CoV-2 induces acute lung injury and mortality in standard laboratory mice
SR Leist, KH Dinnon, A Schäfer, VT Longping, K Okuda, YJ Hou, A West, ...
Cell 183 (4), 1070-1085. e12, 2020
5972020
A single-dose intranasal ChAd vaccine protects upper and lower respiratory tracts against SARS-CoV-2
AO Hassan, NM Kafai, IP Dmitriev, JM Fox, BK Smith, IB Harvey, RE Chen, ...
Cell 183 (1), 169-184. e13, 2020
5642020
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody
CG Rappazzo, LV Tse, CI Kaku, D Wrapp, M Sakharkar, D Huang, ...
Science 371 (6531), 823-829, 2021
3232021
Genomic RNA elements drive phase separation of the SARS-CoV-2 nucleocapsid
C Iserman, CA Roden, MA Boerneke, RSG Sealfon, GA McLaughlin, ...
Molecular cell 80 (6), 1078-1091. e6, 2020
3102020
Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes
WN Voss, YJ Hou, NV Johnson, G Delidakis, JE Kim, K Javanmardi, ...
Science 372 (6546), 1108-1112, 2021
2672021
De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2
TW Linsky, R Vergara, N Codina, JW Nelson, MJ Walker, W Su, ...
Science 370 (6521), 1208-1214, 2020
2032020
Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection
CE Edwards, BL Yount, RL Graham, SR Leist, YJ Hou, KH Dinnon III, ...
Proceedings of the National Academy of Sciences 117 (43), 26915-26925, 2020
1392020
Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome
K Zhang, IN Zheludev, RJ Hagey, R Haslecker, YJ Hou, R Kretsch, ...
Nature Structural & Molecular Biology 28 (9), 747-754, 2021
1222021
Comparison of subgenomic and total RNA in SARS-CoV-2-challenged rhesus macaques
G Dagotto, NB Mercado, DR Martinez, YJ Hou, JP Nkolola, RH Carnahan, ...
Journal of virology 95 (8), 10.1128/jvi. 02370-20, 2021
1222021
Characterization of a pathogenic full-length cDNA clone and transmission model for porcine epidemic diarrhea virus strain PC22A
A Beall, B Yount, CM Lin, Y Hou, Q Wang, L Saif, R Baric
MBio 7 (1), 10.1128/mbio. 01451-15, 2016
912016
Deletion of a 197-amino-acid region in the N-terminal domain of spike protein attenuates porcine epidemic diarrhea virus in piglets
Y Hou, CM Lin, M Yokoyama, BL Yount, D Marthaler, AL Douglas, ...
Journal of virology 91 (14), 10.1128/jvi. 00227-17, 2017
892017
Evaluation of cell-based and surrogate SARS-CoV-2 neutralization assays
AM Sholukh, A Fiore-Gartland, ES Ford, MD Miner, YJ Hou, LV Tse, ...
Journal of Clinical Microbiology 59 (10), 10.1128/jcm. 00527-21, 2021
872021
Deletion of both the tyrosine-based endocytosis signal and the endoplasmic reticulum retrieval signal in the cytoplasmic tail of spike protein attenuates porcine epidemic …
Y Hou, T Meulia, X Gao, LJ Saif, Q Wang
Journal of virology 93 (2), 10.1128/jvi. 01758-18, 2019
672019
Genetic evolution analysis and pathogenicity assessment of porcine epidemic diarrhea virus strains circulating in part of China during 2011–2017
P Chen, K Wang, Y Hou, H Li, X Li, L Yu, Y Jiang, F Gao, W Tong, H Yu, ...
Infection, Genetics and Evolution 69, 153-165, 2019
632019
Attenuation of an original US porcine epidemic diarrhea virus strain PC22A via serial cell culture passage
CM Lin, Y Hou, DG Marthaler, X Gao, X Liu, L Zheng, LJ Saif, Q Wang
Veterinary microbiology 201, 62-71, 2017
622017
Emerging highly virulent porcine epidemic diarrhea virus: molecular mechanisms of attenuation and rational design of live attenuated vaccines
Y Hou, Q Wang
International journal of molecular sciences 20 (21), 5478, 2019
492019
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مقاله‌ها 1–20