Bile acids trigger GLP-1 release predominantly by accessing basolaterally located G protein–coupled bile acid receptors CA Brighton, J Rievaj, RE Kuhre, LL Glass, K Schoonjans, JJ Holst, ... Endocrinology 156 (11), 3961-3970, 2015 | 360 | 2015 |
Bile acids are important direct and indirect regulators of the secretion of appetite-and metabolism-regulating hormones from the gut and pancreas RE Kuhre, NJW Albrechtsen, O Larsen, SL Jepsen, E Balk-Møller, ... Molecular metabolism 11, 84-95, 2018 | 204 | 2018 |
Molecular mechanisms of glucose-stimulated GLP-1 secretion from perfused rat small intestine RE Kuhre, CR Frost, B Svendsen, JJ Holst Diabetes 64 (2), 370-382, 2015 | 178 | 2015 |
Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans RE Kuhre, FM Gribble, B Hartmann, F Reimann, JA Windeløv, JF Rehfeld, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 306 (7 …, 2014 | 138 | 2014 |
The biology of glucagon and the consequences of hyperglucagonemia NJ Wewer Albrechtsen, RE Kuhre, J Pedersen, FK Knop, JJ Holst Biomarkers in medicine 10 (11), 1141-1151, 2016 | 132 | 2016 |
GDF15 promotes weight loss by enhancing energy expenditure in muscle D Wang, LK Townsend, GJ DesOrmeaux, SM Frangos, B Batchuluun, ... Nature 619 (7968), 143-150, 2023 | 114 | 2023 |
Peptide production and secretion in GLUTag, NCI-H716 and STC-1 cells: a comparison to native L-cells RE Kuhre, NJW Albrechtsen, CF Deacon, E Balk-Møller, JF Rehfeld, ... Journal of molecular endocrinology 56 (3), 201, 2016 | 110 | 2016 |
Vascular, but not luminal, activation of FFAR 1 (GPR 40) stimulates GLP‐1 secretion from isolated perfused rat small intestine LW Christensen, RE Kuhre, C Janus, B Svendsen, JJ Holst Physiological Reports 3 (9), e12551, 2015 | 104 | 2015 |
Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis M Winther-Sørensen, KD Galsgaard, A Santos, SAJ Trammell, K Sulek, ... Molecular metabolism 42, 101080, 2020 | 101 | 2020 |
Measurement of the incretin hormones: glucagon-like peptide-1 and glucose-dependent insulinotropic peptide RE Kuhre, NJW Albrechtsen, B Hartmann, CF Deacon, JJ Holst Journal of Diabetes and its Complications 29 (3), 445-450, 2015 | 92 | 2015 |
Stability of glucagon-like peptide 1 and glucagon in human plasma NJW Albrechtsen, MJ Bak, B Hartmann, LW Christensen, RE Kuhre, ... Endocrine connections 4 (1), 50-57, 2015 | 89 | 2015 |
The intestinal distribution pattern of appetite-and glucose regulatory peptides in mice, rats and pigs NJ Wewer Albrechtsen, RE Kuhre, S Toräng, JJ Holst BMC research notes 9, 1-6, 2016 | 79 | 2016 |
No direct effect of SGLT2 activity on glucagon secretion RE Kuhre, SM Ghiasi, AE Adriaenssens, NJ Wewer Albrechtsen, ... Diabetologia 62, 1011-1023, 2019 | 73 | 2019 |
GLP-1 amidation efficiency along the length of the intestine in mice, rats and pigs and in GLP-1 secreting cell lines RE Kuhre, NW Albrechtsen, JA Windeløv, B Svendsen, B Hartmann, ... Peptides 55, 52-57, 2014 | 70 | 2014 |
Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents CB Christiansen, SAJ Trammell, NJ Wewer Albrechtsen, K Schoonjans, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 316 (5 …, 2019 | 65 | 2019 |
Oxyntomodulin identified as a marker of type 2 diabetes and gastric bypass surgery by mass-spectrometry based profiling of human plasma NJW Albrechtsen, D Hornburg, R Albrechtsen, B Svendsen, S Toräng, ... EBioMedicine 7, 112-120, 2016 | 65 | 2016 |
An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles TD Madsen, LH Hansen, J Hintze, Z Ye, S Jebari, DB Andersen, HJ Joshi, ... Nature Communications 11 (1), 4033, 2020 | 61 | 2020 |
Why is it so difficult to measure glucagon-like peptide-1 in a mouse? JA Windeløv, NJ Wewer Albrechtsen, RE Kuhre, SL Jepsen, D Hornburg, ... Diabetologia 60, 2066-2075, 2017 | 55 | 2017 |
The regulation of function, growth and survival of GLP-1-producing L-cells RE Kuhre, JJ Holst, C Kappe Clinical Science 130 (2), 79-91, 2016 | 55 | 2016 |
Deficiency of the GPR39 receptor is associated with obesity and altered adipocyte metabolism PS Petersen, C Jin, AN Madsen, M Rasmussen, R Kuhre, KL Egerod, ... The FASEB Journal 25 (11), 3803-3814, 2011 | 53 | 2011 |