STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4 H Wang, X Huo, XR Yang, J He, L Cheng, N Wang, X Deng, H Jin, ... Molecular cancer 16, 1-15, 2017 | 505 | 2017 |
circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity B Li, L Zhu, C Lu, C Wang, H Wang, H Jin, X Ma, Z Cheng, C Yu, S Wang, ... Nature communications 12 (1), 295, 2021 | 424 | 2021 |
Inducing and exploiting vulnerabilities for the treatment of liver cancer C Wang, S Vegna, H Jin, B Benedict, C Lieftink, C Ramirez, ... Nature 574 (7777), 268-272, 2019 | 366 | 2019 |
circTP63 functions as a ceRNA to promote lung squamous cell carcinoma progression by upregulating FOXM1 Z Cheng, C Yu, S Cui, H Wang, H Jin, C Wang, B Li, M Qin, C Yang, J He, ... Nature communications 10 (1), 3200, 2019 | 309 | 2019 |
EGFR activation limits the response of liver cancer to lenvatinib H Jin, Y Shi, Y Lv, S Yuan, CFA Ramirez, C Lieftink, L Wang, S Wang, ... Nature 595 (7869), 730-734, 2021 | 299 | 2021 |
Rational combinations of targeted cancer therapies: background, advances and challenges H Jin, L Wang, R Bernards Nature Reviews Drug Discovery 22 (3), 213-234, 2023 | 238 | 2023 |
Long noncoding RNA miR503HG, a prognostic indicator, inhibits tumor metastasis by regulating the HNRNPA2B1/NF-κB pathway in hepatocellular carcinoma H Wang, L Liang, Q Dong, L Huan, J He, B Li, C Yang, H Jin, L Wei, C Yu, ... Theranostics 8 (10), 2814, 2018 | 184 | 2018 |
Synergistic cisplatin/doxorubicin combination chemotherapy for multidrug-resistant cancer via polymeric nanogels targeting delivery H Wu, H Jin, C Wang, Z Zhang, H Ruan, L Sun, C Yang, Y Li, W Qin, ... ACS applied materials & interfaces 9 (11), 9426-9436, 2017 | 151 | 2017 |
A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer H Jin, S Wang, EA Zaal, C Wang, H Wu, A Bosma, F Jochems, N Isima, ... Elife 9, e56749, 2020 | 150 | 2020 |
FUN14 Domain‐containing 1–mediated mitophagy suppresses hepatocarcinogenesis by inhibition of inflammasome activation in mice W Li, Y Li, S Siraj, H Jin, Y Fan, X Yang, X Huang, X Wang, J Wang, L Liu, ... Hepatology 69 (2), 604-621, 2019 | 148 | 2019 |
Gas6/Axl axis contributes to chemoresistance and metastasis in breast cancer through Akt/GSK-3β/β-catenin signaling C Wang, H Jin, N Wang, S Fan, Y Wang, Y Zhang, L Wei, X Tao, D Gu, ... Theranostics 6 (8), 1205, 2016 | 145 | 2016 |
The Cancer SENESCopedia: A delineation of cancer cell senescence F Jochems, B Thijssen, G De Conti, R Jansen, Z Pogacar, K Groot, ... Cell reports 36 (4), 2021 | 133 | 2021 |
Heat shock proteins in hepatocellular carcinoma: Molecular mechanism and therapeutic potential C Wang, Y Zhang, K Guo, N Wang, H Jin, Y Liu, W Qin International journal of cancer 138 (8), 1824-1834, 2016 | 130 | 2016 |
PPARγ coactivator‐1α suppresses metastasis of hepatocellular carcinoma by inhibiting Warburg effect by PPARγ–dependent WNT/β‐catenin/pyruvate dehydrogenase kinase isozyme 1 Axis Q Zuo, J He, S Zhang, H Wang, G Jin, H Jin, Z Cheng, X Tao, C Yu, B Li, ... Hepatology 73 (2), 644-660, 2021 | 112 | 2021 |
A novel, liver-specific long noncoding RNA LINC01093 suppresses HCC progression by interaction with IGF2BP1 to facilitate decay of GLI1 mRNA J He, Q Zuo, BO Hu, H Jin, C Wang, Z Cheng, X Deng, C Yang, H Ruan, ... Cancer letters 450, 98-109, 2019 | 112 | 2019 |
COL4A1 promotes the growth and metastasis of hepatocellular carcinoma cells by activating FAK-Src signaling T Wang, H Jin, J Hu, X Li, H Ruan, H Xu, L Wei, W Dong, F Teng, J Gu, ... Journal of Experimental & Clinical Cancer Research 39, 1-16, 2020 | 100 | 2020 |
Phospho-ERK is a biomarker of response to a synthetic lethal drug combination of sorafenib and MEK inhibition in liver cancer C Wang, H Jin, D Gao, C Lieftink, B Evers, G Jin, Z Xue, L Wang, ... Journal of hepatology 69 (5), 1057-1065, 2018 | 96 | 2018 |
CDK12 inhibition mediates DNA damage and is synergistic with sorafenib treatment in hepatocellular carcinoma C Wang, H Wang, C Lieftink, A du Chatinier, D Gao, G Jin, H Jin, ... Gut 69 (4), 727-736, 2020 | 94 | 2020 |
Prognostic significance of kynurenine 3-monooxygenase and effects on proliferation, migration and invasion of human hepatocellular carcinoma H Jin, Y Zhang, H You, X Tao, C Wang, G Jin, N Wang, H Ruan, D Gu, ... Scientific reports 5 (1), 10466, 2015 | 80 | 2015 |
Regulator of calcineurin 1 gene isoform 4, down-regulated in hepatocellular carcinoma, prevents proliferation, migration, and invasive activity of cancer cells and metastasis … H Jin, C Wang, G Jin, H Ruan, D Gu, L Wei, H Wang, N Wang, ... Gastroenterology 153 (3), 799-811. e33, 2017 | 76 | 2017 |