| How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression? BJ Aubrey, GL Kelly, A Janic, MJ Herold, A Strasser Cell death & differentiation 25 (1), 104-113, 2018 | 1402 | 2018 |
| The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models A Kotschy, Z Szlavik, J Murray, J Davidson, AL Maragno, ... Nature 538 (7626), 477-482, 2016 | 1097 | 2016 |
| Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production MJ White, K McArthur, D Metcalf, RM Lane, JC Cambier, MJ Herold, ... Cell 159 (7), 1549-1562, 2014 | 912 | 2014 |
| Emerging connectivity of programmed cell death pathways and its physiological implications S Bedoui, MJ Herold, A Strasser Nature reviews Molecular cell biology 21 (11), 678-695, 2020 | 760 | 2020 |
| Glucocorticoids in T cell apoptosis and function MJ Herold, KG McPherson, HM Reichardt Cellular and molecular life sciences 63, 60-72, 2006 | 505 | 2006 |
| Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia SP Glaser, EF Lee, E Trounson, P Bouillet, A Wei, WD Fairlie, DJ Izon, ... Genes & development 26 (2), 120-125, 2012 | 471 | 2012 |
| An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations in vivo BJ Aubrey, GL Kelly, AJ Kueh, MS Brennan, L O’Connor, L Milla, S Wilcox, ... Cell reports 10 (8), 1422-1432, 2015 | 408 | 2015 |
| NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase‐4 and caspase‐5 PJ Baker, D Boucher, D Bierschenk, C Tebartz, PG Whitney, DB D'Silva, ... European journal of immunology 45 (10), 2918-2926, 2015 | 395 | 2015 |
| The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway LC Rankin, JR Groom, M Chopin, MJ Herold, JA Walker, LA Mielke, ... Nature immunology 14 (4), 389-395, 2013 | 307 | 2013 |
| Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease N Lalaoui, SE Boyden, H Oda, GM Wood, DL Stone, D Chau, L Liu, ... Nature 577 (7788), 103-108, 2020 | 275 | 2020 |
| Glucocorticoids exert opposing effects on macrophage function dependent on their concentration HY Lim, N Müller, MJ Herold, J Van Den Brandt, HM Reichardt Immunology 122 (1), 47-53, 2007 | 268 | 2007 |
| Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells W Pierson, B Cauwe, A Policheni, SM Schlenner, D Franckaert, J Berges, ... Nature immunology 14 (9), 959-965, 2013 | 264 | 2013 |
| Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer D Merino, JR Whittle, F Vaillant, A Serrano, JN Gong, G Giner, ... Science translational medicine 9 (401), eaam7049, 2017 | 200 | 2017 |
| Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats MJ Herold, J van den Brandt, J Seibler, HM Reichardt Proceedings of the National Academy of Sciences 105 (47), 18507-18512, 2008 | 200 | 2008 |
| Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53 GL Kelly, S Grabow, SP Glaser, L Fitzsimmons, BJ Aubrey, T Okamoto, ... Genes & development 28 (1), 58-70, 2014 | 188 | 2014 |
| BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival EF Lee, TJ Harris, S Tran, M Evangelista, S Arulananda, T John, ... Cell death & disease 10 (5), 342, 2019 | 181 | 2019 |
| Myeloid-derived suppressor activity is mediated by monocytic lineages maintained by continuous inhibition of extrinsic and intrinsic death pathways JM Haverkamp, AM Smith, R Weinlich, CP Dillon, JE Qualls, G Neale, ... Immunity 41 (6), 947-959, 2014 | 174 | 2014 |
| The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation SS Ng, F De Labastida Rivera, J Yan, D Corvino, I Das, P Zhang, R Kuns, ... Nature immunology 21 (10), 1205-1218, 2020 | 165 | 2020 |
| Modeling breast cancer using CRISPR-Cas9–mediated engineering of human breast organoids JF Dekkers, JR Whittle, F Vaillant, HR Chen, C Dawson, K Liu, MH Geurts, ... JNCI: Journal of the National Cancer Institute 112 (5), 540-544, 2020 | 164 | 2020 |
| VDAC2 enables BAX to mediate apoptosis and limit tumor development HS Chin, MX Li, IKL Tan, RL Ninnis, B Reljic, K Scicluna, LF Dagley, ... Nature communications 9 (1), 4976, 2018 | 162 | 2018 |
