دنبال کردن
Ajay S. Thatte
Ajay S. Thatte
University of Pennsylvania0
ایمیل تأیید شده در seas.upenn.edu
عنوان
نقل شده توسط
نقل شده توسط
سال
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
KL Swingle, HC Safford, HC Geisler, AG Hamilton, AS Thatte, ...
Journal of the American Chemical Society 145 (8), 4691-4706, 2023
912023
Molecular mechanisms of membrane curvature sensing by a disordered protein
WF Zeno, AS Thatte, L Wang, WT Snead, EM Lafer, JC Stachowiak
Journal of the American Chemical Society 141 (26), 10361-10371, 2019
802019
In vivo mRNA CAR T cell engineering via targeted ionizable lipid nanoparticles with extrahepatic tropism
MM Billingsley, N Gong, AJ Mukalel, AS Thatte, R El‐Mayta, SK Patel, ...
Small 20 (11), 2304378, 2024
552024
Responsive biomaterials: optimizing control of cancer immunotherapy
L Xue, AS Thatte, D Mai, RM Haley, N Gong, X Han, K Wang, ...
Nature Reviews Materials 9 (2), 100-118, 2024
482024
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines
SJ Shepherd, X Han, AJ Mukalel, R El-Mayta, AS Thatte, J Wu, MS Padilla, ...
Proceedings of the National Academy of Sciences 120 (33), e2303567120, 2023
472023
Clathrin senses membrane curvature
WF Zeno, JB Hochfelder, AS Thatte, L Wang, AK Gadok, CC Hayden, ...
Biophysical Journal 120 (5), 818-828, 2021
392021
Structured and intrinsically disordered domains within Amphiphysin1 work together to sense and drive membrane curvature
WF Zeno, WT Snead, AS Thatte, JC Stachowiak
Soft Matter 15 (43), 8706-8717, 2019
332019
Antigen presenting cell mimetic lipid nanoparticles for rapid mRNA CAR T cell cancer immunotherapy
AE Metzloff, MS Padilla, N Gong, MM Billingsley, X Han, M Merolle, D Mai, ...
Advanced Materials 36 (26), 2313226, 2024
252024
Orthogonal design of experiments for engineering of lipid nanoparticles for mRNA delivery to the placenta
HC Safford, KL Swingle, HC Geisler, AG Hamilton, AS Thatte, ...
Small 20 (41), 2303568, 2024
212024
Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery
SK Patel, MM Billingsley, AJ Mukalel, AS Thatte, AG Hamilton, N Gong, ...
Theranostics 14 (1), 1, 2024
202024
Delivery of plasmid DNA by ionizable lipid nanoparticles to induce CAR expression in T cells
PHDM Prazeres, H Ferreira, PAC Costa, W da Silva, MT Alves, M Padilla, ...
International Journal of Nanomedicine, 5891-5904, 2023
172023
mRNA Lipid Nanoparticles for Ex Vivo Engineering of Immunosuppressive T Cells for Autoimmunity Therapies
AS Thatte, AG Hamilton, BE Nachod, AJ Mukalel, MM Billingsley, ...
Nano Letters 23 (22), 10179-10188, 2023
132023
Ionizable lipid nanoparticle-mediated TRAIL mRNA delivery in the tumor microenvironment to inhibit colon cancer progression
WN da Silva, PA Carvalho Costa, SRA Scalzo Júnior, HAS Ferreira, ...
International Journal of Nanomedicine, 2655-2673, 2024
122024
Oxidized mRNA Lipid Nanoparticles for In Situ Chimeric Antigen Receptor Monocyte Engineering
AJ Mukalel, AG Hamilton, MM Billingsley, J Li, AS Thatte, X Han, ...
Advanced Functional Materials 34 (27), 2312038, 2024
122024
EGFR-targeted ionizable lipid nanoparticles enhance in vivo mRNA delivery to the placenta
HC Geisler, AA Ghalsasi, HC Safford, KL Swingle, AS Thatte, AJ Mukalel, ...
Journal of Controlled Release 371, 455-469, 2024
112024
High-Throughput In Vivo Screening Identifies Differential Influences on mRNA Lipid Nanoparticle Immune Cell Delivery by Administration Route
AG Hamilton, KL Swingle, AS Thatte, AJ Mukalel, HC Safford, ...
ACS nano 18 (25), 16151-16165, 2024
72024
Emerging strategies for nanomedicine in autoimmunity
AS Thatte, MM Billingsley, D Weissman, JR Melamed, MJ Mitchell
Advanced Drug Delivery Reviews 207, 115194, 2024
72024
In utero delivery of targeted ionizable lipid nanoparticles facilitates in vivo gene editing of hematopoietic stem cells
R Palanki, JS Riley, SK Bose, V Luks, A Dave, N Kus, BM White, ...
Proceedings of the National Academy of Sciences 121 (32), e2400783121, 2024
52024
Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia
KL Swingle, AG Hamilton, HC Safford, HC Geisler, AS Thatte, R Palanki, ...
Nature 637 (8045), 412-421, 2025
42025
Fine-tuning extracellular fluid viscosity enhances gene delivery
AS Thatte, D Kim, MJ Mitchell
Nature Chemical Engineering 1 (9), 559-560, 2024
2024
سیستم در حال حاضر قادر به انجام عملکرد نیست. بعداً دوباره امتحان کنید.
مقاله‌ها 1–20