دنبال کردن
Lewis Cantley
Lewis Cantley
Dana Farber Cancer Center and Harvard Medical School
ایمیل تأیید شده در med.cornell.edu
عنوان
نقل شده توسط
نقل شده توسط
سال
Understanding the Warburg effect: the metabolic requirements of cell proliferation
MG Vander Heiden, LC Cantley, CB Thompson
science 324 (5930), 1029-1033, 2009
175362009
AKT/PKB signaling: navigating downstream
BD Manning, LC Cantley
Cell 129 (7), 1261-1274, 2007
75572007
The phosphoinositide 3-kinase pathway
LC Cantley
Science 296 (5573), 1655-1657, 2002
74242002
MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
JA Engelman, K Zejnullahu, T Mitsudomi, Y Song, C Hyland, JO Park, ...
science 316 (5827), 1039-1043, 2007
55102007
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
L Dang, DW White, S Gross, BD Bennett, MA Bittinger, EM Driggers, ...
Nature 462 (7274), 739-744, 2009
48542009
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
JA Engelman, J Luo, LC Cantley
Nature Reviews Genetics 7 (8), 606-619, 2006
40512006
SH2 domains recognize specific phosphopeptide sequences
S Zhou, SE Shoelson, M Chaudhuri, G Gish, T Pawson, WG Haser, F King, ...
Cell 72 (5), 767-778, 1993
35671993
Oncogenes and signal transduction
LC Cantley, KR Auger, C Carpenter, B Duckworth, A Graziani, R Kapeller, ...
Cell 64 (2), 281-302, 1991
35511991
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
HR Christofk, MG Vander Heiden, MH Harris, A Ramanathan, ...
Nature 452 (7184), 230-233, 2008
32892008
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ...
Nature 475 (7354), 106-109, 2011
2957*2011
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
LC Cantley, BG Neel
Proceedings of the National Academy of Sciences 96 (8), 4240-4245, 1999
27641999
Ras, PI (3) K and mTOR signalling controls tumour cell growth
RJ Shaw, LC Cantley
Nature 441 (7092), 424-430, 2006
26542006
The PI3K pathway in human disease
DA Fruman, H Chiu, BD Hopkins, S Bagrodia, LC Cantley, RT Abraham
Cell 170 (4), 605-635, 2017
24532017
PI3K pathway alterations in cancer: variations on a theme
TL Yuan, LC Cantley
Oncogene 27 (41), 5497-5510, 2008
24482008
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
RJ Shaw, KA Lamia, D Vasquez, SH Koo, N Bardeesy, RA DePinho, ...
Science 310 (5754), 1642-1646, 2005
24192005
PI3K: downstream AKTion blocks apoptosis
TF Franke, DR Kaplan, LC Cantley
Cell 88 (4), 435-437, 1997
21941997
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
RJ Shaw, M Kosmatka, N Bardeesy, RL Hurley, LA Witters, RA DePinho, ...
Proceedings of the National Academy of Sciences 101 (10), 3329-3335, 2004
21762004
Phosphoinositide kinases
DA Fruman, RE Meyers, LC Cantley
Annual review of biochemistry 67 (1), 481-507, 1998
21531998
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
H Ying, AC Kimmelman, CA Lyssiotis, S Hua, GC Chu, ...
Cell 149 (3), 656-670, 2012
21372012
Bidirectional transport of amino acids regulates mTOR and autophagy
P Nicklin, P Bergman, B Zhang, E Triantafellow, H Wang, B Nyfeler, ...
Cell 136 (3), 521-534, 2009
20452009
سیستم در حال حاضر قادر به انجام عملکرد نیست. بعداً دوباره امتحان کنید.
مقاله‌ها 1–20