دنبال کردن
Els Pardon
Els Pardon
ایمیل تأیید شده در vub.ac.be
عنوان
نقل شده توسط
نقل شده توسط
سال
Crystal structure of the β2 adrenergic receptor–Gs protein complex
SGF Rasmussen, BT DeVree, Y Zou, AC Kruse, KY Chung, TS Kobilka, ...
Nature 477 (7366), 549-555, 2011
35782011
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
SGF Rasmussen, HJ Choi, JJ Fung, E Pardon, P Casarosa, PS Chae, ...
Nature 469 (7329), 175-180, 2011
20482011
Activation and allosteric modulation of a muscarinic acetylcholine receptor
AC Kruse, AM Ring, A Manglik, J Hu, K Hu, K Eitel, H Hübner, E Pardon, ...
Nature 504 (7478), 101-106, 2013
9982013
A general protocol for the generation of Nanobodies for structural biology
E Pardon, T Laeremans, S Triest, SGF Rasmussen, A Wohlkönig, A Ruf, ...
Nature protocols 9 (3), 674-693, 2014
8212014
GABAA receptor signalling mechanisms revealed by structural pharmacology
S Masiulis, R Desai, T Uchański, I Serna Martin, D Laverty, D Karia, ...
Nature 565 (7740), 454-459, 2019
5452019
Mutations in PMM2, a phosphomannomutase gene on chromosome 16p13 in carbohydrate-deficient glycoprotein type I syndrome (Jaeken syndrome)
G Matthijs, E Schollen, E Pardon, M Veiga-Da-Cunha, J Jaeken, ...
Nature genetics 16 (1), 88-92, 1997
4241997
Structure of the nanobody-stabilized active state of the kappa opioid receptor
T Che, S Majumdar, SA Zaidi, P Ondachi, JD McCorvy, S Wang, ...
Cell 172 (1), 55-67. e15, 2018
3952018
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation
DP Staus, RT Strachan, A Manglik, B Pani, AW Kahsai, TH Kim, ...
Nature 535 (7612), 448-452, 2016
3522016
Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer
D Laverty, R Desai, T Uchański, S Masiulis, WJ Stec, T Malinauskas, ...
Nature 565 (7740), 516-520, 2019
3282019
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
AB Ward, P Szewczyk, V Grimard, CW Lee, L Martinez, R Doshi, A Caya, ...
Proceedings of the National Academy of Sciences 110 (33), 13386-13391, 2013
2992013
Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies
D Saerens, M Pellis, R Loris, E Pardon, M Dumoulin, A Matagne, L Wyns, ...
Journal of molecular biology 352 (3), 597-607, 2005
2952005
Allosteric coupling from G protein to the agonist-binding pocket in GPCRs
BT DeVree, JP Mahoney, GA Vélez-Ruiz, SGF Rasmussen, AJ Kuszak, ...
Nature 535 (7610), 182-186, 2016
2922016
Structural flexibility of the Gαs α-helical domain in the β2-adrenoceptor Gs complex
GH Westfield, SGF Rasmussen, M Su, S Dutta, BT DeVree, KY Chung, ...
Proceedings of the National Academy of Sciences 108 (38), 16086-16091, 2011
2912011
The molecular mechanism of transport by the mitochondrial ADP/ATP carrier
JJ Ruprecht, MS King, T Zögg, AA Aleksandrova, E Pardon, PG Crichton, ...
Cell 176 (3), 435-447. e15, 2019
2822019
Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes
K Rostislavleva, N Soler, Y Ohashi, L Zhang, E Pardon, JE Burke, ...
Science 350 (6257), aac7365, 2015
2672015
Structures of β-klotho reveal a ‘zip code’-like mechanism for endocrine FGF signalling
S Lee, J Choi, J Mohanty, LP Sousa, F Tome, E Pardon, J Steyaert, ...
Nature 553 (7689), 501-505, 2018
2342018
Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody
KV Korotkov, E Pardon, J Steyaert, WGJ Hol
Structure 17 (2), 255-265, 2009
2262009
Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport
IA Ehrnstorfer, ER Geertsma, E Pardon, J Steyaert, R Dutzler
Nature Structural & Molecular Biology 21 (11), 990-996, 2014
2162014
Structure and properties of a complex of α-synuclein and a single-domain camelid antibody
EJ De Genst, T Guilliams, J Wellens, EM O'day, CA Waudby, S Meehan, ...
Journal of molecular biology 402 (2), 326-343, 2010
2162010
Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist
M Masureel, Y Zou, LP Picard, E van der Westhuizen, JP Mahoney, ...
Nature chemical biology 14 (11), 1059-1066, 2018
1972018
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مقاله‌ها 1–20