Excitotoxicity, calcium and mitochondria: a triad in synaptic neurodegeneration M Verma, BN Lizama, CT Chu Translational neurodegeneration 11 (1), 3, 2022 | 272 | 2022 |
Silent scaffolds: inhibition of c-Jun N-terminal kinase 3 activity in cell by dominant-negative arrestin-3 mutant M Breitman, S Kook, LE Gimenez, BN Lizama, MC Palazzo, EV Gurevich, ... Journal of Biological Chemistry 287 (23), 19653-19664, 2012 | 101 | 2012 |
Neuronal autophagy and mitophagy in Parkinson's disease BN Lizama, CT Chu Molecular aspects of medicine 82, 100972, 2021 | 92 | 2021 |
Redox modification of proteins as essential mediators of CNS autophagy and mitophagy B Lizama-Manibusan, BA McLaughlin FEBS letters 587 (15), 2291-2298, 2013 | 49 | 2013 |
CHIP is an essential determinant of neuronal mitochondrial stress signaling AM Palubinsky, JN Stankowski, AC Kale, SG Codreanu, RJ Singer, ... Antioxidants & redox signaling 23 (6), 535-549, 2015 | 38 | 2015 |
Neuronal preconditioning requires the mitophagic activity of C-terminus of HSC70-interacting protein BN Lizama, AM Palubinsky, VA Raveendran, AM Moore, JD Federspiel, ... Journal of Neuroscience 38 (31), 6825-6840, 2018 | 35 | 2018 |
Sigma-2 receptors—from basic biology to therapeutic target: a focus on age-related degenerative diseases BN Lizama, J Kahle, SM Catalano, AO Caggiano, M Grundman, ... International journal of molecular sciences 24 (7), 6251, 2023 | 26 | 2023 |
Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation K N. Grelli, A M. Palubinsky, A Cozette Kale, BN Lizama-Manibusan, ... CNS & Neurological Disorders-Drug Targets-CNS & Neurological Disorders) 12 …, 2013 | 16 | 2013 |
Alterations in the E3 ligases Parkin and CHIP result in unique metabolic signaling defects and mitochondrial quality control issues BN Lizama, AM Palubinsky, BA McLaughlin Neurochemistry international 117, 139-155, 2018 | 12 | 2018 |
Analysis of a nitroreductase-based hypoxia sensor in primary neuronal cultures BN Lizama-Manibusan, S Klein, JR McKenzie, DE Cliffel, BA McLaughlin ACS chemical neuroscience 7 (9), 1188-1191, 2016 | 12 | 2016 |
Endogenous PTEN-induced kinase 1 regulates dendritic architecture and spinogenesis PA Otero, G Fricklas, A Nigam, BN Lizama, ZP Wills, JW Johnson, CT Chu Journal of Neuroscience 42 (41), 7848-7860, 2022 | 7 | 2022 |
iPSC-derived neurons from patients with POLG mutations exhibit decreased mitochondrial content and dendrite simplification M Verma, L Francis, BN Lizama, J Callio, G Fricklas, KZQ Wang, ... The American Journal of Pathology 193 (2), 201-212, 2023 | 6 | 2023 |
Excitotoxicity, calcium and mitochondria: a triad in synaptic neurodegeneration. Transl Neurodegener. 2022; 11 (1): 3 M Verma, BN Lizama, CT Chu Epub 2022/01/27. https://doi. org/10.1186/s40035-021-00278-7 PMID: 35078537, 0 | 5 | |
An interim exploratory proteomics biomarker analysis of a phase 2 clinical trial to assess the impact of CT1812 in Alzheimer's disease BN Lizama, HA North, K Pandey, C Williams, D Duong, E Cho, V Di Caro, ... Neurobiology of Disease 199, 106575, 2024 | 4 | 2024 |
PINK1: multiple mechanisms of neuroprotection BN Lizama, PA Otero, CT Chu International review of movement disorders 2, 193-219, 2021 | 3 | 2021 |
CT1812 biomarker signature from a meta‐analysis of CSF proteomic findings from two Phase 2 clinical trials in Alzheimer's disease BN Lizama, C Williams, HA North, K Pandey, D Duong, V Di Caro, ... Alzheimer's & Dementia 20 (10), 6860-6880, 2024 | 1 | 2024 |
Differentiated retinal pigment epithelial cells as a model for uncovering sigma-2 receptor functions and novel therapeutics for dry AMD A Reaver, BN Lizama, E Cho, V Di Caro, A Caggiano, ME Hamby Investigative Ophthalmology & Visual Science 65 (7), 5006-5006, 2024 | 1 | 2024 |
Unbiased transcriptomic analysis of the sigma-2 receptor modulator CT1812 in cell-based models of dry age-related macular degeneration BN Lizama, L Waybright, E Malagise, E Watto, A Caggiano, ME Hamby Investigative Ophthalmology & Visual Science 64 (8), 2119-2119, 2023 | 1 | 2023 |
Genetic Models of Parkinson’s Disease: Behavior, Signaling, and Pathological Features AM Palubinsky, BN Lizama-Manibusan, D Miller, BA McLaughlin Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders …, 2015 | 1 | 2015 |
Sigma-2 receptor modulator CT1812 alters key pathways and rescues retinal pigment epithelium (RPE) functional deficits associated with dry age-related macular degeneration (AMD) BN Lizama, E Keeling, E Cho, EM Malagise, N Knezovich, L Waybright, ... Scientific Reports 15 (1), 4256, 2025 | | 2025 |