دنبال کردن
Britney N. Lizama
Britney N. Lizama
Cognition Therapeutics, Inc.
ایمیل تأیید شده در cogrx.com
عنوان
نقل شده توسط
نقل شده توسط
سال
Excitotoxicity, calcium and mitochondria: a triad in synaptic neurodegeneration
M Verma, BN Lizama, CT Chu
Translational neurodegeneration 11 (1), 3, 2022
2722022
Silent scaffolds: inhibition of c-Jun N-terminal kinase 3 activity in cell by dominant-negative arrestin-3 mutant
M Breitman, S Kook, LE Gimenez, BN Lizama, MC Palazzo, EV Gurevich, ...
Journal of Biological Chemistry 287 (23), 19653-19664, 2012
1012012
Neuronal autophagy and mitophagy in Parkinson's disease
BN Lizama, CT Chu
Molecular aspects of medicine 82, 100972, 2021
922021
Redox modification of proteins as essential mediators of CNS autophagy and mitophagy
B Lizama-Manibusan, BA McLaughlin
FEBS letters 587 (15), 2291-2298, 2013
492013
CHIP is an essential determinant of neuronal mitochondrial stress signaling
AM Palubinsky, JN Stankowski, AC Kale, SG Codreanu, RJ Singer, ...
Antioxidants & redox signaling 23 (6), 535-549, 2015
382015
Neuronal preconditioning requires the mitophagic activity of C-terminus of HSC70-interacting protein
BN Lizama, AM Palubinsky, VA Raveendran, AM Moore, JD Federspiel, ...
Journal of Neuroscience 38 (31), 6825-6840, 2018
352018
Sigma-2 receptors—from basic biology to therapeutic target: a focus on age-related degenerative diseases
BN Lizama, J Kahle, SM Catalano, AO Caggiano, M Grundman, ...
International journal of molecular sciences 24 (7), 6251, 2023
262023
Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation
K N. Grelli, A M. Palubinsky, A Cozette Kale, BN Lizama-Manibusan, ...
CNS & Neurological Disorders-Drug Targets-CNS & Neurological Disorders) 12 …, 2013
162013
Alterations in the E3 ligases Parkin and CHIP result in unique metabolic signaling defects and mitochondrial quality control issues
BN Lizama, AM Palubinsky, BA McLaughlin
Neurochemistry international 117, 139-155, 2018
122018
Analysis of a nitroreductase-based hypoxia sensor in primary neuronal cultures
BN Lizama-Manibusan, S Klein, JR McKenzie, DE Cliffel, BA McLaughlin
ACS chemical neuroscience 7 (9), 1188-1191, 2016
122016
Endogenous PTEN-induced kinase 1 regulates dendritic architecture and spinogenesis
PA Otero, G Fricklas, A Nigam, BN Lizama, ZP Wills, JW Johnson, CT Chu
Journal of Neuroscience 42 (41), 7848-7860, 2022
72022
iPSC-derived neurons from patients with POLG mutations exhibit decreased mitochondrial content and dendrite simplification
M Verma, L Francis, BN Lizama, J Callio, G Fricklas, KZQ Wang, ...
The American Journal of Pathology 193 (2), 201-212, 2023
62023
Excitotoxicity, calcium and mitochondria: a triad in synaptic neurodegeneration. Transl Neurodegener. 2022; 11 (1): 3
M Verma, BN Lizama, CT Chu
Epub 2022/01/27. https://doi. org/10.1186/s40035-021-00278-7 PMID: 35078537, 0
5
An interim exploratory proteomics biomarker analysis of a phase 2 clinical trial to assess the impact of CT1812 in Alzheimer's disease
BN Lizama, HA North, K Pandey, C Williams, D Duong, E Cho, V Di Caro, ...
Neurobiology of Disease 199, 106575, 2024
42024
PINK1: multiple mechanisms of neuroprotection
BN Lizama, PA Otero, CT Chu
International review of movement disorders 2, 193-219, 2021
32021
CT1812 biomarker signature from a meta‐analysis of CSF proteomic findings from two Phase 2 clinical trials in Alzheimer's disease
BN Lizama, C Williams, HA North, K Pandey, D Duong, V Di Caro, ...
Alzheimer's & Dementia 20 (10), 6860-6880, 2024
12024
Differentiated retinal pigment epithelial cells as a model for uncovering sigma-2 receptor functions and novel therapeutics for dry AMD
A Reaver, BN Lizama, E Cho, V Di Caro, A Caggiano, ME Hamby
Investigative Ophthalmology & Visual Science 65 (7), 5006-5006, 2024
12024
Unbiased transcriptomic analysis of the sigma-2 receptor modulator CT1812 in cell-based models of dry age-related macular degeneration
BN Lizama, L Waybright, E Malagise, E Watto, A Caggiano, ME Hamby
Investigative Ophthalmology & Visual Science 64 (8), 2119-2119, 2023
12023
Genetic Models of Parkinson’s Disease: Behavior, Signaling, and Pathological Features
AM Palubinsky, BN Lizama-Manibusan, D Miller, BA McLaughlin
Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders …, 2015
12015
Sigma-2 receptor modulator CT1812 alters key pathways and rescues retinal pigment epithelium (RPE) functional deficits associated with dry age-related macular degeneration (AMD)
BN Lizama, E Keeling, E Cho, EM Malagise, N Knezovich, L Waybright, ...
Scientific Reports 15 (1), 4256, 2025
2025
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مقاله‌ها 1–20