دنبال کردن
Michael A. DeJesus
Michael A. DeJesus
Bioinformatics, Rockefeller University
ایمیل تأیید شده در rockefeller.edu - صفحهٔ اصلی
عنوان
نقل شده توسط
نقل شده توسط
سال
High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism
JE Griffin, JD Gawronski, MA DeJesus, TR Ioerger, BJ Akerley, ...
PLoS pathogens 7 (9), e1002251, 2011
11782011
Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis
MA DeJesus, ER Gerrick, W Xu, SW Park, JE Long, CC Boutte, EJ Rubin, ...
MBio 8 (1), 10.1128/mbio. 02133-16, 2017
6192017
TRANSIT-a software tool for Himar1 TnSeq analysis
MA DeJesus, C Ambadipudi, R Baker, C Sassetti, TR Ioerger
PLoS computational biology 11 (10), e1004401, 2015
2262015
Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis
B Bosch, MA DeJesus, NC Poulton, W Zhang, CA Engelhart, A Zaveri, ...
Cell 184 (17), 4579-4592. e24, 2021
2102021
CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis
S Li, NC Poulton, JS Chang, ZA Azadian, MA DeJesus, N Ruecker, ...
Nature microbiology 7 (6), 766-779, 2022
1192022
Chemical genetic interaction profiling reveals determinants of intrinsic antibiotic resistance in Mycobacterium tuberculosis
W Xu, MA DeJesus, N Rücker, CA Engelhart, MG Wright, C Healy, K Lin, ...
Antimicrobial agents and chemotherapy 61 (12), 10.1128/aac. 01334-17, 2017
1122017
A Hidden Markov Model for identifying essential and growth-defect regions in bacterial genomes from transposon insertion sequencing data
MA DeJesus, TR Ioerger
BMC bioinformatics 14, 1-12, 2013
1032013
Identifying Essential Genes in Mycobacterium tuberculosis by Global Phenotypic Profiling
JE Long, M DeJesus, D Ward, RE Baker, T Ioerger, CM Sassetti
Gene Essentiality: Methods and Protocols, 79-95, 2015
1022015
Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries
MA DeJesus, YJ Zhang, CM Sassetti, EJ Rubin, JC Sacchettini, ...
Bioinformatics 29 (6), 695-703, 2013
982013
Behavioral and transcriptomic profiling of mice null for Lphn3, a gene implicated in ADHD and addiction
CA Orsini, B Setlow, M DeJesus, S Galaviz, K Loesch, T Ioerger, D Wallis
Molecular genetics & genomic medicine 4 (3), 322-343, 2016
612016
Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice
J Korte, M Alber, CM Trujillo, K Syson, H Koliwer-Brandl, R Deenen, ...
PLoS pathogens 12 (12), e1006043, 2016
482016
Statistical analysis of genetic interactions in Tn-Seq data
MA DeJesus, S Nambi, CM Smith, RE Baker, CM Sassetti, TR Ioerger
Nucleic acids research 45 (11), e93-e93, 2017
422017
Reannotation of translational start sites in the genome of Mycobacterium tuberculosis
MA DeJesus, JC Sacchettini, TR Ioerger
Tuberculosis 93 (1), 18-25, 2013
382013
Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression
S Subramaniyam, MA DeJesus, A Zaveri, CM Smith, RE Baker, S Ehrt, ...
BMC bioinformatics 20, 1-15, 2019
242019
CRISPR Interference Reveals That All-Trans-Retinoic Acid Promotes Macrophage Control of Mycobacterium tuberculosis by Limiting Bacterial Access to …
GH Babunovic, MA DeJesus, B Bosch, MR Chase, T Barbier, AK Dickey, ...
MBio 13 (1), e03683-21, 2022
232022
Normalization of transposon-mutant library sequencing datasets to improve identification of conditionally essential genes
MA DeJesus, TR Ioerger
Journal of bioinformatics and computational biology 14 (03), 1642004, 2016
192016
Mutations in rv0678 Confer Low-Level Resistance to Benzothiazinone DprE1 Inhibitors in Mycobacterium tuberculosis
NC Poulton, ZA Azadian, MA DeJesus, JM Rock
Antimicrobial Agents and Chemotherapy 66 (9), e00904-22, 2022
182022
Beyond antibiotic resistance: the whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria
NC Poulton, MA DeJesus, V Munsamy-Govender, M Kanai, CG Roberts, ...
Cell Chemical Biology 31 (4), 669-682. e7, 2024
122024
The Mycobacterium tuberculosis transposon sequencing database (MtbTnDB): a large-scale guide to genetic conditional essentiality
A Jinich, A Zaveri, MA DeJesus, E Flores-Bautista, CM Smith, CM Sassetti, ...
bioRxiv, 2021.03. 05.434127, 2021
122021
Compensatory evolution in NusG improves fitness of drug-resistant M. tuberculosis
KA Eckartt, M Delbeau, V Munsamy-Govender, MA DeJesus, ZA Azadian, ...
Nature 628 (8006), 186-194, 2024
112024
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مقاله‌ها 1–20