Novel activities of CYP11A1 and their potential physiological significance AT Slominski, W Li, TK Kim, I Semak, J Wang, JK Zjawiony, RC Tuckey The Journal of steroid biochemistry and molecular biology 151, 25-37, 2015 | 299 | 2015 |
RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy-and 20, 23-dihydroxyvitamin D AT Slominski, TK Kim, Y Takeda, Z Janjetovic, AA Broz, C Skobowiat, ... The FASEB Journal 28 (7), 2775, 2014 | 295 | 2014 |
New substituted 4H-chromenes as anticancer agents SA Patil, J Wang, XS Li, J Chen, TS Jones, A Hosni-Ahmed, R Patil, ... Bioorganic & medicinal chemistry letters 22 (13), 4458-4461, 2012 | 143 | 2012 |
Discovery of novel 2-aryl-4-benzoyl-imidazole (ABI-III) analogues targeting tubulin polymerization as antiproliferative agents J Chen, S Ahn, J Wang, Y Lu, JT Dalton, DD Miller, W Li Journal of medicinal chemistry 55 (16), 7285-7289, 2012 | 123 | 2012 |
In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland AT Slominski, TK Kim, HZ Shehabi, EKY Tang, HAE Benson, I Semak, ... Molecular and cellular endocrinology 383 (1-2), 181-192, 2014 | 109 | 2014 |
20-hydroxyvitamin D3 inhibits proliferation of cancer cells with high efficacy while being non-toxic J Wang, A Slominski, RC Tuckey, Z Janjetovic, A Kulkarni, J Chen, ... Anticancer research 32 (3), 739-746, 2012 | 100 | 2012 |
20S-Hydroxyvitamin D3, Noncalcemic Product of CYP11A1 Action on Vitamin D3, Exhibits Potent Antifibrogenic Activity in Vivo A Slominski, Z Janjetovic, RC Tuckey, MN Nguyen, KG Bhattacharya, ... The Journal of Clinical Endocrinology & Metabolism 98 (2), E298-E303, 2013 | 97 | 2013 |
Design, synthesis, and biological evaluation of stable colchicine binding site tubulin inhibitors as potential anticancer agents Y Lu, J Chen, J Wang, CM Li, S Ahn, CM Barrett, JT Dalton, W Li, ... Journal of medicinal chemistry 57 (17), 7355-7366, 2014 | 95 | 2014 |
Synthesis and antiproliferative activity of novel 2-aryl-4-benzoyl-imidazole derivatives targeting tubulin polymerization J Chen, CM Li, J Wang, S Ahn, Z Wang, Y Lu, JT Dalton, DD Miller, W Li Bioorganic & medicinal chemistry 19 (16), 4782-4795, 2011 | 88 | 2011 |
A comprehensive review of cytochrome P450 2E1 for xenobiotic metabolism J Chen, S Jiang, J Wang, J Renukuntla, S Sirimulla, J Chen Drug metabolism reviews 51 (2), 178-195, 2019 | 81 | 2019 |
Correlation between secosteroid-induced vitamin D receptor activity in melanoma cells and computer-modeled receptor binding strength TK Kim, J Wang, Z Janjetovic, J Chen, RC Tuckey, MN Nguyen, EKY Tang, ... Molecular and cellular endocrinology 361 (1-2), 143-152, 2012 | 79 | 2012 |
Exosome is a mechanism of intercellular drug transfer: Application of quantitative pharmacology J Wang, BZ Yeung, M Cui, CJ Peer, Z Lu, WD Figg, MG Wientjes, S Woo, ... Journal of Controlled Release 268, 147-158, 2017 | 77 | 2017 |
Discovery of novel resorcinol dibenzyl ethers targeting the programmed cell death-1/programmed cell death–ligand 1 interaction as potential anticancer agents B Cheng, Y Ren, X Niu, W Wang, S Wang, Y Tu, S Liu, J Wang, D Yang, ... Journal of medicinal chemistry 63 (15), 8338-8358, 2020 | 73 | 2020 |
Novel vitamin D analogs as potential therapeutics: metabolism, toxicity profiling, and antiproliferative activity J Chen, J Wang, TK Kim, EW Tieu, EKY Tang, Z Lin, D Kovacic, DD Miller, ... Anticancer research 34 (5), 2153-2163, 2014 | 67 | 2014 |
Novel tubulin polymerization inhibitors overcome multidrug resistance and reduce melanoma lung metastasis Z Wang, J Chen, J Wang, S Ahn, CM Li, Y Lu, VS Loveless, JT Dalton, ... Pharmaceutical research 29, 3040-3052, 2012 | 67 | 2012 |
Discovery of novel second mitochondria-derived activator of caspase mimetics as selective inhibitor of apoptosis protein inhibitors J Wang, W Li The Journal of pharmacology and experimental therapeutics 349 (2), 319-329, 2014 | 66 | 2014 |
Discovery of 4-Aryl-2-benzoyl-imidazoles as tubulin polymerization inhibitor with potent antiproliferative properties M Xiao, S Ahn, J Wang, J Chen, DD Miller, JT Dalton, W Li Journal of medicinal chemistry 56 (8), 3318-3329, 2013 | 64 | 2013 |
Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and mouse CYP27B1 EKY Tang, J Chen, Z Janjetovic, EW Tieu, AT Slominski, W Li, RC Tuckey Drug Metabolism and Disposition 41 (5), 1112-1124, 2013 | 52 | 2013 |
Novel compaction techniques with pellet-containing granules X Pan, M Chen, K Han, X Peng, X Wen, B Chen, J Wang, G Li, C Wu European journal of pharmaceutics and biopharmaceutics 75 (3), 436-442, 2010 | 44 | 2010 |
Synergistic Combination of Novel Tubulin Inhibitor ABI-274 and Vemurafenib Overcomes Vemurafenib Acquired Resistance in BRAFV600E Melanoma J Wang, J Chen, DD Miller, W Li Molecular cancer therapeutics 13 (1), 16-26, 2014 | 42 | 2014 |