One-pot synthesis and molecular modeling studies of new bioactive spiro-oxindoles based on uracil derivatives as SARS-CoV-2 inhibitors targeting RNA polymerase and spike … SA El-Kalyoubi, A Ragab, OA Abu Ali, YA Ammar, MG Seadawy, A Ahmed, ... Pharmaceuticals 15 (3), 376, 2022 | 50 | 2022 |
One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines SA El-Kalyoubi, EA Fayed, AS Abdel-Razek Chemistry Central Journal 11, 1-13, 2017 | 40 | 2017 |
In vitro antimicrobial evaluation and in silico studies of coumarin derivatives tagged with pyrano-pyridine and pyrano-pyrimidine moieties as DNA gyrase inhibitors EA Fayed, ES Nosseir, A Atef, SA El‑Kalyoubi Molecular Diversity, 1-23, 2022 | 38 | 2022 |
Synthesis, in silico prediction and in vitro evaluation of antimicrobial activity, dft calculation and theoretical investigation of novel xanthines and uracil containing … S El-Kalyoubi, F Agili, WA Zordok, ASA El-Sayed International Journal of Molecular Sciences 22 (20), 10979, 2021 | 29 | 2021 |
Synthesis and evaluation of antitumour activities of novel fused tri-and tetracyclic uracil derivatives S ElKalyoubi, E Fayed Journal of Chemical Research 40 (12), 771-777, 2016 | 26 | 2016 |
Synthesis, DNA binding and antiviral activity of new uracil, xanthine, and pteridine derivatives OI El‐Sabbagh, ME El‐Sadek, S El‐Kalyoubi, I Ismail Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 2007 | 26 | 2007 |
Synthesis, In Silico Prediction and In Vitro Evaluation of Antitumor Activities of Novel Pyrido[2,3-d]pyrimidine, Xanthine and Lumazine Derivatives S El-Kalyoubi, F Agili Molecules 25 (21), 5205, 2020 | 22 | 2020 |
Novel uracil derivatives depicted potential anticancer agents: in vitro, molecular docking, and ADME study S El-Kalyoubi, F Agili, I Adel, MA Tantawy Arabian Journal of Chemistry 15 (4), 103669, 2022 | 21 | 2022 |
A novel synthesis of fused uracils: indenopyrimidopyridazines, pyrimidopyridazines, and pyrazolopyrimidines for antimicrobial and antitumor evalution S El-Kalyoubi, F Agili Molecules 21 (12), 1714, 2016 | 21 | 2016 |
Synthesis and anticancer evaluation of some novel pyrimido[5,4-e][1,2,4]triazines and pyrazolo[3,4-d]pyrimidine using DMF-DMA as methylating and cyclizing agent SA El-Kalyoubi Chemistry Central Journal 12, 1-14, 2018 | 17 | 2018 |
Synthesis, characterization and antimicrobial activities of some 5-bromouracil metal ion complexes SM Teleb, ME Askar, SA El-Kalyoubi, AS Gaballa Bulletin of the Chemical Society of Ethiopia 33 (2), 255-268, 2019 | 16 | 2019 |
Design and synthesis of new spirooxindole candidates and their selenium nanoparticles as potential dual Topo I/II inhibitors, DNA intercalators, and apoptotic inducers S El-Kalyoubi, MM Khalifa, MT Abo-Elfadl, AA El-Sayed, A Elkamhawy, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2242714, 2023 | 15 | 2023 |
Novel 2-thioxanthine and dipyrimidopyridine derivatives: synthesis and antimicrobial activity S El-kalyoubi, F Agili, S Youssif Molecules 20 (10), 19263-19276, 2015 | 13 | 2015 |
Design, Synthesis, and Anti-Proliferative Action of Purine/Pteridine-Based Derivatives as Dual Inhibitors of EGFR and BRAFV600E SA El-Kalyoubi, HAM Gomaa, EMN Abdelhafez, M Ramadan, F Agili, ... Pharmaceuticals 16 (5), 716, 2023 | 12 | 2023 |
Uracil as a Zn-binding bioisostere of the allergic benzenesulfonamide in the design of quinoline–uracil hybrids as anticancer carbonic anhydrase inhibitors SA El-Kalyoubi, ES Taher, TS Ibrahim, MF El-Behairy, AMM Al-Mahmoudy Pharmaceuticals 15 (5), 494, 2022 | 11 | 2022 |
Synthesis, DFT calculations, and anti-proliferative evaluation of pyrimidine and selenadiazolopyrimidine derivatives as dual Topoisomerase II and HSP90 inhibitors S El-Kalyoubi, SA El-Sebaey, AM Rashad, HA Al-Ghulikah, MM Ghorab, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2198163, 2023 | 10 | 2023 |
A novel one-pot and efficient procedure for synthesis of new fused uracil derivatives for DNA binding BA Mousa, AH Bayoumi, MM Korraa, MG Assy, SA El-Kalyoubi International Journal of Organic Chemistry 5 (1), 37-47, 2015 | 10 | 2015 |
Design, synthesis, and biological evaluation of new potential unusual modified anticancer immunomodulators for possible non-teratogenic quinazoline-based thalidomide analogs RR Mabrouk, AE Abdallah, HA Mahdy, SA El-Kalyoubi, OJ Kamal, ... International Journal of Molecular Sciences 24 (15), 12416, 2023 | 9 | 2023 |
Synthesis, molecular docking and anticancer activity of some 5‐aryl‐5, 10‐dihydropyrido [2, 3‐d: 6, 5‐d′] dipyrimidine‐2, 4, 6, 8‐tetraone derivatives and pyrido [2, 3‐d … B Farag, F Agili, S El‐Kalyoubi, SA Said, S Youssif, W Shehta ChemistrySelect 7 (7), e202103834, 2022 | 9 | 2022 |
Design and synthesis of novel uracil-linked Schiff bases as dual histone deacetylase type II/topoisomerase type I inhibitors with apoptotic potential S El-Kalyoubi, SS Elbaramawi, AG Eissa, E Al-Ageeli, YH Hobani, ... Future Medicinal Chemistry 15 (11), 937-958, 2023 | 8 | 2023 |