| MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response M Fabbri, A Paone, F Calore, R Galli, E Gaudio, R Santhanam, F Lovat, ... Proceedings of the National Academy of Sciences 109 (31), E2110-E2116, 2012 | 1744 | 2012 |
| miRNA signatures associate with pathogenesis and progression of osteosarcoma KB Jones, Z Salah, S Del Mare, M Galasso, E Gaudio, GJ Nuovo, F Lovat, ... Cancer research 72 (7), 1865-1877, 2012 | 418 | 2012 |
| The BET bromodomain inhibitor OTX015 affects pathogenetic pathways in preclinical B-cell tumor models and synergizes with targeted drugs M Boi, E Gaudio, P Bonetti, I Kwee, E Bernasconi, C Tarantelli, A Rinaldi, ... Clinical Cancer Research 21 (7), 1628-1638, 2015 | 329 | 2015 |
| Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression KC Kurek, S Del Mare, Z Salah, S Abdeen, H Sadiq, S Lee, E Gaudio, ... Cancer research 70 (13), 5577-5586, 2010 | 126 | 2010 |
| Association of Wwox with ErbB4 in breast cancer RI Aqeilan, V Donati, E Gaudio, MS Nicoloso, M Sundvall, A Korhonen, ... Cancer research 67 (19), 9330-9336, 2007 | 125 | 2007 |
| PQR309 is a novel dual PI3K/mTOR inhibitor with preclinical antitumor activity in lymphomas as a single agent and in combination therapy C Tarantelli, E Gaudio, AJ Arribas, I Kwee, P Hillmann, A Rinaldi, ... Clinical Cancer Research 24 (1), 120-129, 2018 | 118 | 2018 |
| Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms M Sundvall, A Korhonen, I Paatero, E Gaudio, G Melino, CM Croce, ... Proceedings of the National Academy of Sciences 105 (11), 4162-4167, 2008 | 112 | 2008 |
| Physical association with WWOX suppresses c-Jun transcriptional activity E Gaudio, A Palamarchuk, T Palumbo, F Trapasso, Y Pekarsky, CM Croce, ... Cancer research 66 (24), 11585-11589, 2006 | 109 | 2006 |
| Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells F Trapasso, F Pichiorri, M Gaspari, T Palumbo, RI Aqeilan, E Gaudio, ... Journal of Biological Chemistry 283 (20), 13736-13744, 2008 | 105 | 2008 |
| PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27Kip1 C Nicholas, J Yang, SB Peters, MA Bill, RA Baiocchi, F Yan, S Sïf, S Tae, ... PLoS One 8 (9), e74710, 2013 | 99 | 2013 |
| Targeted ablation of the WW domain-containing oxidoreductase tumor suppressor leads to impaired steroidogenesis RI Aqeilan, JP Hagan, A De Bruin, M Rawahneh, Z Salah, E Gaudio, ... Endocrinology 150 (3), 1530-1535, 2009 | 82 | 2009 |
| Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma R Chilà, A Basana, M Lupi, F Guffanti, E Gaudio, A Rinaldi, L Cascione, ... Oncotarget 6 (5), 3394, 2014 | 73 | 2014 |
| New molecular and therapeutic insights into canine diffuse large B cell lymphoma elucidates the role of the dog as a model for human disease L Aresu, S Ferraresso, L Marconato, L Cascione, S Napoli, E Gaudio, ... Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018 | 71 | 2018 |
| Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies E Gaudio, R Spizzo, F Paduano, Z Luo, A Efanov, A Palamarchuk, ... Blood, The Journal of the American Society of Hematology 119 (1), 180-187, 2012 | 67 | 2012 |
| Antitumor activity of the dual BET and CBP/EP300 inhibitor NEO2734 F Spriano, E Gaudio, L Cascione, C Tarantelli, F Melle, G Motta, V Priebe, ... Blood advances 4 (17), 4124-4135, 2020 | 65 | 2020 |
| Genetic Ablation of Ptprj, a Mouse Cancer Susceptibility Gene, Results in Normal Growth and Development and Does Not Predispose to Spontaneous Tumorigenesis F Trapasso, A Drusco, S Costinean, H Alder, RI Aqeilan, R Iuliano, ... DNA and cell biology 25 (6), 376-382, 2006 | 62 | 2006 |
| The ETS inhibitors YK-4-279 and TK-216 are novel antilymphoma agents F Spriano, EYL Chung, E Gaudio, C Tarantelli, L Cascione, S Napoli, ... Clinical Cancer Research 25 (16), 5167-5176, 2019 | 54 | 2019 |
| Pyrrolo[2′,3′:3,4]cyclohepta[1,2-d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types V Spano, R Rocca, M Barreca, D Giallombardo, A Montalbano, ... Journal of medicinal chemistry 63 (20), 12023-12042, 2020 | 52 | 2020 |
| Fhit–Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells T Druck, DG Cheung, D Park, F Trapasso, F Pichiorri, M Gaspari, ... Cell death & disease 10 (3), 147, 2019 | 48 | 2019 |
| Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma E Bernasconi, E Gaudio, P Lejeune, C Tarantelli, L Cascione, I Kwee, ... British journal of haematology 178 (6), 936-948, 2017 | 45 | 2017 |