دنبال کردن
Panu Luukkonen
Panu Luukkonen
Minerva Foundation Institute for Medical Research, University of Helsinki and University Hospital
ایمیل تأیید شده در helsinki.fi
عنوان
نقل شده توسط
نقل شده توسط
سال
Hepatic ceramides dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease
PK Luukkonen, Y Zhou, S Sädevirta, M Leivonen, J Arola, M Orešič, ...
Journal of hepatology 64 (5), 1167-1175, 2016
4842016
Saturated fat is more metabolically harmful for the human liver than unsaturated fat or simple sugars
PK Luukkonen, S Sädevirta, Y Zhou, B Kayser, A Ali, L Ahonen, ...
Diabetes care 41 (8), 1732-1739, 2018
4392018
Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically characterised cohort☆
QM Anstee, R Darlay, S Cockell, M Meroni, O Govaere, D Tiniakos, ...
Journal of hepatology 73 (3), 505-515, 2020
4342020
Quantitative PCR provides a simple and accessible method for quantitative microbiota profiling
C Jian, P Luukkonen, H Yki-Järvinen, A Salonen, K Korpela
PloS one 15 (1), e0227285, 2020
3662020
Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: A systematic review and meta-analysis
EA Selvaraj, FE Mózes, ANA Jayaswal, MH Zafarmand, Y Vali, JA Lee, ...
Journal of hepatology 75 (4), 770-785, 2021
2982021
Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease
PK Luukkonen, S Dufour, K Lyu, XM Zhang, A Hakkarainen, TE Lehtimäki, ...
Proceedings of the National Academy of Sciences 117 (13), 7347-7354, 2020
2252020
Dietary carbohydrates and fats in nonalcoholic fatty liver disease
H Yki-Järvinen, PK Luukkonen, L Hodson, JB Moore
Nature reviews Gastroenterology & hepatology 18 (11), 770-786, 2021
2102021
Exposure to environmental contaminants is associated with altered hepatic lipid metabolism in non-alcoholic fatty liver disease
P Sen, S Qadri, PK Luukkonen, O Ragnarsdottir, A McGlinchey, S Jäntti, ...
Journal of hepatology 76 (2), 283-293, 2022
2002022
The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans
PK Luukkonen, Y Zhou, T Hyotylainen, M Leivonen, J Arola, ...
Journal of hepatology 65 (6), 1263-1265, 2016
1922016
Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids
PK Luukkonen, A Nick, M Hölttä-Vuori, C Thiele, E Isokuortti, ...
JCI insight 4 (16), e127902, 2019
1522019
Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD
PK Luukkonen, Y Zhou, PAN Haridas, OP Dwivedi, T Hyötyläinen, A Ali, ...
Journal of hepatology 67 (1), 128-136, 2017
1512017
Distinct contributions of metabolic dysfunction and genetic risk factors in the pathogenesis of non-alcoholic fatty liver disease
PK Luukkonen, S Qadri, N Ahlholm, K Porthan, V Männistö, ...
Journal of hepatology 76 (3), 526-535, 2022
1472022
Exome-wide association study on alanine aminotransferase identifies sequence variants in the GPAM and APOE associated with fatty liver disease
O Jamialahmadi, RM Mancina, E Ciociola, F Tavaglione, PK Luukkonen, ...
Gastroenterology 160 (5), 1634-1646. e7, 2021
1232021
rs641738C> T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis
K Teo, KWM Abeysekera, L Adams, E Aigner, QM Anstee, JM Banales, ...
Journal of hepatology 74 (1), 20-30, 2021
1232021
A membrane-bound diacylglycerol species induces PKCϵ-mediated hepatic insulin resistance
K Lyu, Y Zhang, D Zhang, M Kahn, KW Ter Horst, MRS Rodrigues, ...
Cell metabolism 32 (4), 654-664. e5, 2020
1232020
LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover
Y Tanaka, Y Shimanaka, A Caddeo, T Kubo, Y Mao, T Kubota, N Kubota, ...
Gut 70 (1), 180-193, 2021
1202021
Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease
PK Luukkonen, T Tukiainen, A Juuti, H Sammalkorpi, PAN Haridas, ...
JCI insight 5 (5), e132158, 2020
922020
MARC1 variant rs2642438 increases hepatic phosphatidylcholines and decreases severity of non-alcoholic fatty liver disease in humans
PK Luukkonen, A Juuti, H Sammalkorpi, AK Penttilä, M Oresic, ...
Journal of Hepatology 73 (3), 725-726, 2020
682020
Impact of short-term overfeeding of saturated or unsaturated fat or sugars on the gut microbiota in relation to liver fat in obese and overweight adults
C Jian, P Luukkonen, S Sädevirta, H Yki-Järvinen, A Salonen
Clinical Nutrition 40 (1), 207-216, 2021
542021
Obesity modifies the performance of fibrosis biomarkers in nonalcoholic fatty liver disease
S Qadri, N Ahlholm, I Lønsmann, P Pellegrini, A Poikola, PK Luukkonen, ...
The Journal of Clinical Endocrinology & Metabolism 107 (5), e2008-e2020, 2022
502022
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مقاله‌ها 1–20