Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass … KE Swearingen, SE Lindner, L Shi, MJ Shears, A Harupa, CS Hopp, ... PLoS pathogens 12 (4), e1005606, 2016 | 198 | 2016 |
Lipid profile remodeling in response to nitrogen deprivation in the microalgae Chlorella sp.(Trebouxiophyceae) and Nannochloropsis sp.(Eustigmatophyceae) GJO Martin, DRA Hill, ILD Olmstead, A Bergamin, MJ Shears, DA Dias, ... PLoS One 9 (8), e103389, 2014 | 148 | 2014 |
Atypical lipid composition in the purified relict plastid (apicoplast) of malaria parasites CY Botté, Y Yamaryo-Botté, TWT Rupasinghe, KA Mullin, JI MacRae, ... Proceedings of the National Academy of Sciences 110 (18), 7506-7511, 2013 | 146 | 2013 |
Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites SE Lindner, KE Swearingen, MJ Shears, MP Walker, EN Vrana, KJ Hart, ... Nature communications 10 (1), 4964, 2019 | 122 | 2019 |
Fatty acid metabolism in the Plasmodium apicoplast: Drugs, doubts and knockouts MJ Shears, CY Botté, GI McFadden Molecular and biochemical parasitology 199 (1-2), 34-50, 2015 | 114 | 2015 |
Multi-step screening of DNA/lipid nanoparticles and co-delivery with siRNA to enhance and prolong gene expression Y Zhu, R Shen, I Vuong, RA Reynolds, MJ Shears, ZC Yao, Y Hu, WJ Cho, ... Nature communications 13 (1), 4282, 2022 | 88 | 2022 |
Apicoplast-Localized Lysophosphatidic Acid Precursor Assembly Is Required for Bulk Phospholipid Synthesis in Toxoplasma gondii and Relies on an Algal/Plant … S Amiar, JI MacRae, DL Callahan, D Dubois, GG van Dooren, MJ Shears, ... PLoS pathogens 12 (8), e1005765, 2016 | 67 | 2016 |
Division and adaptation to host environment of apicomplexan parasites depend on apicoplast lipid metabolic plasticity and host organelle remodeling S Amiar, NJ Katris, L Berry, S Dass, S Duley, CS Arnold, MJ Shears, ... Cell Reports 30 (11), 3778-3792. e9, 2020 | 57 | 2020 |
Alpha-v–containing integrins are host receptors for the Plasmodium falciparum sporozoite surface protein, TRAP K Dundas, MJ Shears, Y Sun, CS Hopp, C Crosnier, T Metcalf, G Girling, ... Proceedings of the National Academy of Sciences 115 (17), 4477-4482, 2018 | 55 | 2018 |
Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity Y Zhu, J Ma, R Shen, J Lin, S Li, X Lu, JL Stelzel, J Kong, L Cheng, ... Nature biomedical engineering 8 (5), 544-560, 2024 | 39 | 2024 |
Proteomic Analysis of Plasmodium Merosomes: The Link between Liver and Blood Stages in Malaria MJ Shears, R Sekhar Nirujogi, KE Swearingen, S Renuse, S Mishra, ... Journal of proteome research 18 (9), 3404-3418, 2019 | 36 | 2019 |
Important extracellular interactions between Plasmodium sporozoites and host cells required for infection K Dundas, MJ Shears, P Sinnis, GJ Wright Trends in parasitology 35 (2), 129-139, 2019 | 36 | 2019 |
Characterization of the Plasmodium falciparum and P. berghei glycerol 3‐phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite … MJ Shears, JI MacRae, V Mollard, CD Goodman, A Sturm, LM Orchard, ... Cellular microbiology 19 (1), e12633, 2017 | 36 | 2017 |
Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness S Mok, T Yeo, D Hong, MJ Shears, LS Ross, KE Ward, SK Dhingra, ... Science Advances 9 (45), eadi2364, 2023 | 23 | 2023 |
O-Fucosylation of thrombospondin-like repeats is required for processing of microneme protein 2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites G Bandini, DR Leon, CM Hoppe, Y Zhang, C Agop-Nersesian, MJ Shears, ... Journal of Biological Chemistry 294 (6), 1967-1983, 2019 | 23 | 2019 |
Generation of transmission-competent human malaria parasites with chromosomally-integrated fluorescent reporters KJ McLean, J Straimer, CS Hopp, J Vega-Rodriguez, JL Small-Saunders, ... Scientific reports 9 (1), 13131, 2019 | 22 | 2019 |
Cryopreserved sporozoites with and without the glycolipid adjuvant 7DW8-5 protect in prime-and-trap malaria vaccination FN Watson, MJ Shears, J Matsubara, AC Kalata, AM Seilie, IC Talavera, ... The American Journal of Tropical Medicine and Hygiene 106 (4), 1227, 2022 | 13 | 2022 |
AIM2 sensors mediate immunity to Plasmodium infection in hepatocytes C Marques-da-Silva, B Poudel, RP Baptista, K Peissig, LS Hancox, ... Proceedings of the National Academy of Sciences 120 (2), e2210181120, 2023 | 11 | 2023 |
Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine Z MacMillen, K Hatzakis, A Simpson, MJ Shears, F Watson, JH Erasmus, ... npj Vaccines 9 (1), 12, 2024 | 10 | 2024 |
Quantification of Plasmodium knowlesi versus Plasmodium falciparum in the rhesus liver: implications for malaria vaccine studies in rhesus models MJ Shears, AM Seilie, B Kim Lee Sim, SL Hoffman, SC Murphy Malaria Journal 19, 1-9, 2020 | 10 | 2020 |