| Enantioselective CH crotylation of primary alcohols via hydrohydroxyalkylation of butadiene JR Zbieg, E Yamaguchi, EL McInturff, MJ Krische Science 336 (6079), 324-327, 2012 | 347 | 2012 |
| Simple catalytic mechanism for the direct coupling of α-carbonyls with functionalized amines: a one-step synthesis of plavix RW Evans, JR Zbieg, S Zhu, W Li, DWC MacMillan Journal of the American Chemical Society 135 (43), 16074-16077, 2013 | 204 | 2013 |
| Diastereo- and Enantioselective Ruthenium-Catalyzed Hydrohydroxyalkylation of 2-Silyl-butadienes: Carbonyl syn-Crotylation from the Alcohol Oxidation Level JR Zbieg, J Moran, MJ Krische Journal of the American Chemical Society 133 (27), 10582-10586, 2011 | 140 | 2011 |
| GDC-9545 (Giredestrant): a potent and orally bioavailable selective estrogen receptor antagonist and degrader with an exceptional preclinical profile for ER+ breast cancer J Liang, JR Zbieg, RA Blake, JH Chang, S Daly, AG DiPasquale, ... Journal of Medicinal Chemistry 64 (16), 11841-11856, 2021 | 117 | 2021 |
| Small molecule dysregulation of TEAD lipidation induces a dominant-negative inhibition of hippo pathway signaling JK Holden, JJ Crawford, CL Noland, S Schmidt, JR Zbieg, JA Lacap, ... Cell reports 31 (12), 2020 | 115 | 2020 |
| Visible-light photocatalysis as an enabling technology for drug discovery: a paradigm shift for chemical reactivity P Li, JA Terrett, JR Zbieg ACS medicinal chemistry letters 11 (11), 2120-2130, 2020 | 103 | 2020 |
| Direct, redox-neutral prenylation and geranylation of secondary carbinol C–H bonds: C4-regioselectivity in ruthenium-catalyzed C–C couplings of dienes to α-hydroxy esters JC Leung, LM Geary, TY Chen, JR Zbieg, MJ Krische Journal of the American Chemical Society 134 (38), 15700-15703, 2012 | 103 | 2012 |
| anti-Aminoallylation of Aldehydes via Ruthenium-Catalyzed Transfer Hydrogenative Coupling of Sulfonamido Allenes: 1,2-Aminoalcohols E Skucas, JR Zbieg, MJ Krische Journal of the American Chemical Society 131 (14), 5054-5055, 2009 | 100 | 2009 |
| An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance TJ Hagenbeek, JR Zbieg, M Hafner, R Mroue, JA Lacap, NM Sodir, ... Nature Cancer 4 (6), 812-828, 2023 | 98 | 2023 |
| RORγ antagonists and inverse agonists: a patent review SM Bronner, JR Zbieg, JJ Crawford Expert opinion on therapeutic patents 27 (1), 101-112, 2017 | 91 | 2017 |
| Amplification of Anti-Diastereoselectivity via Curtin− Hammett Effects in Ruthenium-Catalyzed Hydrohydroxyalkylation of 1, 1-Disubstituted Allenes: Diastereoselective Formation … JR Zbieg, EL McInturff, JC Leung, MJ Krische Journal of the American Chemical Society 133 (4), 1141-1144, 2011 | 90 | 2011 |
| Allenamide Hydro−Hydroxyalkylation: 1,2-Amino Alcohols via Ruthenium-Catalyzed Carbonyl anti-Aminoallylation JR Zbieg, EL McInturff, MJ Krische Organic letters 12 (11), 2514-2516, 2010 | 88 | 2010 |
| Hippo pathway inhibition by blocking the YAP/TAZ–TEAD interface: a patent review JJ Crawford, SM Bronner, JR Zbieg Expert opinion on therapeutic patents 28 (12), 867-873, 2018 | 79 | 2018 |
| Regio‐and Enantioselective Iridium‐Catalyzed N‐Allylation of Indoles and Related Azoles with Racemic Branched Alkyl‐Substituted Allylic Acetates SW Kim, TT Schempp, JR Zbieg, CE Stivala, MJ Krische Angewandte Chemie 131 (23), 7844-7848, 2019 | 60 | 2019 |
| Amphiphilic π-Allyliridium C,O-Benzoates Enable Regio- and Enantioselective Amination of Branched Allylic Acetates Bearing Linear Alkyl Groups AT Meza, T Wurm, L Smith, SW Kim, JR Zbieg, CE Stivala, MJ Krische Journal of the American Chemical Society 140 (4), 1275-1279, 2018 | 57 | 2018 |
| Regio-and enantioselective iridium-catalyzed amination of racemic branched alkyl-substituted allylic acetates with primary and secondary aromatic and heteroaromatic amines SW Kim, LA Schwartz, JR Zbieg, CE Stivala, MJ Krische Journal of the American Chemical Society 141 (1), 671-676, 2018 | 56 | 2018 |
| Iridium‐Catalyzed Hydrohydroxyalkylation of Butadiene: Carbonyl Crotylation JR Zbieg, T Fukuzumi, MJ Krische Advanced synthesis & catalysis 352 (14‐15), 2416-2420, 2010 | 56 | 2010 |
| Transition-metal-catalyzed asymmetric allylation of carbonyl compounds with unsaturated hydrocarbons PS Wang, ML Shen, LZ Gong Synthesis 50 (05), 956-967, 2018 | 46 | 2018 |
| Tetrahydro-pyrido [3, 4-b] indole estrogen receptor modulators and uses thereof S Labadie, J Liang, DF Ortwine, X Wang, J Zbieg, B Zhang, SC Goodacre, ... US Patent 9,980,947, 2018 | 44 | 2018 |
| Enantioselective iridium-catalyzed vinylogous Reformatsky-aldol reaction from the alcohol oxidation level: linear regioselectivity by way of carbon-bound enolates A Hassan, JR Zbieg, MJ Krische Angewandte Chemie (International ed. in English) 50 (15), 3493, 2011 | 42 | 2011 |
