دنبال کردن
Thierry Kogej
Thierry Kogej
Associate Principal Scientist, AstraZeneca
ایمیل تأیید شده در astrazeneca.com
عنوان
نقل شده توسط
نقل شده توسط
سال
Design of organic molecules with large two-photon absorption cross sections‏
M Albota, D Beljonne, JL Brédas, JE Ehrlich, JY Fu, AA Heikal, SE Hess, ...‏
Science 281 (5383), 1653-1656, 1998‏
27921998
Generating focused molecule libraries for drug discovery with recurrent neural networks‏
MHS Segler, T Kogej, C Tyrchan, MP Waller‏
ACS central science 4 (1), 120-131, 2017‏
16132017
Mechanisms for enhancement of two-photon absorption in donor–acceptor conjugated chromophores‏
T Kogej, D Beljonne, F Meyers, JW Perry, SR Marder, JL Brédas‏
Chemical Physics Letters 298 (1-3), 1-6, 1998‏
4091998
Designing novel building blocks is an overlooked strategy to improve compound quality‏
FW Goldberg, JG Kettle, T Kogej, MWD Perry, NP Tomkinson‏
Drug Discovery Today 20 (1), 11-17, 2015‏
2162015
Tuning the two-photon absorption response of quadrupolar organic molecules‏
E Zojer, D Beljonne, T Kogej, H Vogel, SR Marder, JW Perry, JL Bredas‏
The Journal of chemical physics 116 (9), 3646-3658, 2002‏
1532002
Datasets and their influence on the development of computer assisted synthesis planning tools in the pharmaceutical domain‏
A Thakkar, T Kogej, JL Reymond, O Engkvist, EJ Bjerrum‏
Chemical science 11 (1), 154-168, 2020‏
1492020
Straightforward strategies for the preparation of NH-sulfoximines: a serendipitous story‏
JA Bull, L Degennaro, R Luisi‏
Synlett 28 (19), 2525-2538, 2017‏
1312017
ChemGPS-NPWeb: chemical space navigation online‏
J Rosén, A Lövgren, T Kogej, S Muresan, J Gottfries, A Backlund‏
Journal of computer-aided molecular design 23, 253-259, 2009‏
1212009
Secondary metabolites from cetrarioid lichens: Chemotaxonomy, biological activities and pharmaceutical potential‏
M Xu, S Heidmarsson, ES Olafsdottir, R Buonfiglio, T Kogej, S Omarsdottir‏
Phytomedicine 23 (5), 441-459, 2016‏
1022016
Making every SAR point count: the development of Chemistry Connect for the large-scale integration of structure and bioactivity data‏
S Muresan, P Petrov, C Southan, MJ Kjellberg, T Kogej, C Tyrchan, ...‏
Drug Discovery Today 16 (23-24), 1019-1030, 2011‏
982011
Multifingerprint based similarity searches for targeted class compound selection‏
T Kogej, O Engkvist, N Blomberg, S Muresan‏
Journal of chemical information and modeling 46 (3), 1201-1213, 2006‏
902006
Big pharma screening collections: more of the same or unique libraries? The AstraZeneca–Bayer Pharma AG case‏
T Kogej, N Blomberg, PJ Greasley, S Mundt, MJ Vainio, J Schamberger, ...‏
Drug discovery today 18 (19-20), 1014-1024, 2013‏
802013
Comparison of molecular fingerprint methods on the basis of biological profile data‏
A Steffen, T Kogej, C Tyrchan, O Engkvist‏
Journal of chemical information and modeling 49 (2), 338-347, 2009‏
722009
On the use of real-world datasets for reaction yield prediction‏
M Saebi, B Nan, JE Herr, J Wahlers, Z Guo, AM Zurański, T Kogej, ...‏
Chemical science 14 (19), 4997-5005, 2023‏
702023
LibINVENT: Reaction-based Generative Scaffold Decoration for in Silico Library Design‏
V Fialková, J Zhao, K Papadopoulos, O Engkvist, EJ Bjerrum, T Kogej, ...‏
Journal of Chemical Information and Modeling 62 (9), 2046-2063, 2021‏
702021
Cheminformatics in drug discovery, an industrial perspective‏
H Chen, T Kogej, O Engkvist‏
Molecular Informatics 37 (9-10), 1800041, 2018‏
632018
Applications of deep-learning in exploiting large-scale and heterogeneous compound data in industrial pharmaceutical research‏
L David, J Arús-Pous, J Karlsson, O Engkvist, EJ Bjerrum, T Kogej, ...‏
Frontiers in pharmacology 10, 1303, 2019‏
592019
Science1998, 281, 1653‏
M Albota, D Beljonne, JL Brédas, JE Ehrlich, JY Fu, AA Heikal, SE Hess, ...‏
There is no corresponding record for this reference, 0‏
56
AI-assisted synthesis prediction‏
S Johansson, A Thakkar, T Kogej, E Bjerrum, S Genheden, T Bastys, ...‏
Drug Discovery Today: Technologies 32, 65-72, 2019‏
542019
Pyrazolone methylamino piperidine derivatives as novel CCR3 antagonists‏
C Pégurier, P Collart, P Danhaive, S Defays, M Gillard, F Gilson, T Kogej, ...‏
Bioorganic & medicinal chemistry letters 17 (15), 4228-4231, 2007‏
542007
سیستم در حال حاضر قادر به انجام عملکرد نیست. بعداً دوباره امتحان کنید.
مقاله‌ها 1–20