Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export P Lei, S Ayton, DI Finkelstein, L Spoerri, GD Ciccotosto, DK Wright, ... Nature medicine 18 (2), 291-295, 2012 | 676 | 2012 |
NFIB mediates BRN2 driven melanoma cell migration and invasion through regulation of EZH2 and MITF ME Fane, Y Chhabra, DEJ Hollingsworth, JL Simmons, L Spoerri, TG Oh, ... EBioMedicine 16, 63-75, 2017 | 90 | 2017 |
Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure MP Smith, EJ Rowling, Z Miskolczi, J Ferguson, L Spoerri, NK Haass, ... EMBO molecular medicine 9 (8), 1011-1029, 2017 | 73 | 2017 |
Real-time cell cycle imaging in a 3D cell culture model of melanoma L Spoerri, KA Beaumont, A Anfosso, NK Haass 3D Cell Culture: Methods and Protocols, 401-416, 2017 | 54 | 2017 |
DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma S Pavey, L Spoerri, NK Haass, B Gabrielli Pigment cell & melanoma research 26 (6), 805-816, 2013 | 37 | 2013 |
The amyloid precursor protein copper binding domain histidine residues 149 and 151 mediate APP stability and metabolism L Spoerri, LJ Vella, CLL Pham, KJ Barnham, R Cappai Journal of Biological Chemistry 287 (32), 26840-26853, 2012 | 37 | 2012 |
Amyloid precursor protein and amyloid precursor‐like protein 2 have distinct roles in modulating myelination, demyelination, and remyelination of axons PH Truong, GD Ciccotosto, TD Merson, L Spoerri, MJ Chuei, M Ayers, ... Glia 67 (3), 525-538, 2019 | 27 | 2019 |
Mathematical model of tumour spheroid experiments with real-time cell cycle imaging W Jin, L Spoerri, NK Haass, MJ Simpson Bulletin of Mathematical Biology 83, 1-23, 2021 | 26 | 2021 |
Defective decatenation checkpoint function is a common feature of melanoma K Brooks, KM Chia, L Spoerri, P Mukhopadhyay, M Wigan, M Stark, ... Journal of Investigative Dermatology 134 (1), 150-158, 2014 | 25 | 2014 |
Fluorescence-based quantitative and spatial analysis of tumour spheroids: a proposed tool to predict patient-specific therapy response L Spoerri, G Gunasingh, NK Haass Frontiers in Digital Health 3, 668390, 2021 | 20 | 2021 |
Endogenous Replication Stress Marks Melanomas Sensitive to CHEK1 Inhibitors In Vivo ZY Oo, AJ Stevenson, M Proctor, SM Daignault, S Walpole, C Lanagan, ... Clinical Cancer Research 24 (12), 2901-2912, 2018 | 20 | 2018 |
Cell cycle checkpoint and DNA damage response defects as anticancer targets: From molecular mechanisms to therapeutic opportunities L Spoerri, ZY Oo, JE Larsen, NK Haass, B Gabrielli, S Pavey Stress response pathways in cancer: From molecular targets to novel …, 2015 | 18 | 2015 |
A novel ATM‐dependent checkpoint defect distinct from loss of function mutation promotes genomic instability in melanoma L Spoerri, K Brooks, KM Chia, G Grossman, JJ Ellis, M Dahmer‐Heath, ... Pigment cell & melanoma research 29 (3), 329-339, 2016 | 16 | 2016 |
Phenotypic melanoma heterogeneity is regulated through cell-matrix interaction-dependent changes in tumor microarchitecture L Spoerri, CA Tonnessen-Murray, G Gunasingh, DS Hill, KA Beaumont, ... BioRxiv, 2020.06. 09.141747, 2020 | 15* | 2020 |
Decatenation checkpoint‐defective melanomas are dependent on PI 3K for survival K Brooks, M Ranall, L Spoerri, A Stevenson, G Gunasingh, S Pavey, ... Pigment cell & melanoma research 27 (5), 813-821, 2014 | 13 | 2014 |
Reciprocal regulation of BRN2 and NOTCH1/2 signaling synergistically drives melanoma cell migration and invasion ME Fane, Y Chhabra, L Spoerri, JL Simmons, R Ludwig, E Bonvin, ... Journal of Investigative Dermatology 142 (7), 1845-1857, 2022 | 3 | 2022 |
Similar, not the same: diverse roles and regulation of cyclin Es L Spoerri, B Gabrielli Cell Cycle 12 (5), 715-715, 2013 | 2 | 2013 |
Role of the Amyloid Precursor Protein and Copper in Alzheimer’s Disease L Spoerri, KJ Barnham, G Multhaup, R Cappai Brain Diseases and Metalloproteins, 181-232, 2012 | 2 | 2012 |
Environmentally stressed drug-naive melanoma cell subpopulations share a molecular signature with drug-induced early persister cells SA Kangachar, F Ahmed, A Al Emran, G Boyle, L Spoerri, H Schaider, ... Journal of Investigative Dermatology 144 (8), S109-S109, 2024 | | 2024 |
Real-Time Cell Cycle Imaging in a 3D Cell Culture Model of Melanoma, Quantitative Analysis, Optical Clearing, and Mathematical Modeling L Spoerri, KA Beaumont, A Anfosso, RJ Murphy, AP Browning, ... 3D Cell Culture: Methods and Protocols, 291-310, 2024 | | 2024 |