| Hydrogen sulfide protects from colitis and restores intestinal microbiota biofilm and mucus production JP Motta, KL Flannigan, TA Agbor, JK Beatty, RW Blackler, ... Inflammatory bowel diseases 21 (5), 1006-1017, 2015 | 214 | 2015 |
| Anti-inflammatory and cytoprotective actions of hydrogen sulfide: translation to therapeutics JL Wallace, RW Blackler, MV Chan, GJ Da Silva, W Elsheikh, ... Antioxidants & redox signaling 22 (5), 398-410, 2015 | 177 | 2015 |
| Cutting edge: IL-36 receptor promotes resolution of intestinal damage O Medina-Contreras, A Harusato, H Nishio, KL Flannigan, V Ngo, G Leoni, ... The Journal of Immunology 196 (1), 34-38, 2016 | 146 | 2016 |
| IL-17A-mediated neutrophil recruitment limits expansion of segmented filamentous bacteria KL Flannigan, VL Ngo, D Geem, A Harusato, SA Hirota, CA Parkos, ... Mucosal immunology 10 (3), 673-684, 2017 | 137 | 2017 |
| Gaseous mediators in resolution of inflammation JL Wallace, A Ianaro, KL Flannigan, G Cirino Seminars in immunology 27 (3), 227-233, 2015 | 126 | 2015 |
| Vancomycin relieves mycophenolate mofetil–induced gastrointestinal toxicity by eliminating gut bacterial β-glucuronidase activity MR Taylor, KL Flannigan, H Rahim, A Mohamud, IA Lewis, SA Hirota, ... Science advances 5 (8), eaax2358, 2019 | 106 | 2019 |
| Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis KL Flannigan, TA Agbor, RW Blackler, JJ Kim, WI Khan, EF Verdu, ... Proceedings of the National Academy of Sciences 111 (37), 13559-13564, 2014 | 99 | 2014 |
| Segmented filamentous bacteria‐induced immune responses: a balancing act between host protection and autoimmunity KL Flannigan, TL Denning Immunology 154 (4), 537-546, 2018 | 96 | 2018 |
| An intact microbiota is required for the gastrointestinal toxicity of the immunosuppressant mycophenolate mofetil KL Flannigan, MR Taylor, SK Pereira, J Rodriguez-Arguello, AW Moffat, ... The Journal of Heart and Lung Transplantation 37 (9), 1047-1059, 2018 | 84 | 2018 |
| Enhanced synthesis and diminished degradation of hydrogen sulfide in experimental colitis: a site-specific, pro-resolution mechanism KL Flannigan, JGP Ferraz, R Wang, JL Wallace PLoS One 8 (8), e71962, 2013 | 83 | 2013 |
| Eukaryotic and prokaryotic contributions to colonic hydrogen sulfide synthesis KL Flannigan, KD McCoy, JL Wallace American Journal of Physiology-Gastrointestinal and Liver Physiology 301 (1 …, 2011 | 79 | 2011 |
| Deciphering the pathogenesis of NSAID enteropathy using proton pump inhibitors and a hydrogen sulfide-releasing NSAID RW Blackler, G De Palma, A Manko, GJ Da Silva, KL Flannigan, P Bercik, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 308 (12 …, 2015 | 74 | 2015 |
| Intestinal antigen-presenting cells: key regulators of immune homeostasis and inflammation KL Flannigan, D Geem, A Harusato, TL Denning The American journal of pathology 185 (7), 1809-1819, 2015 | 68 | 2015 |
| Targeting the pregnane X receptor using microbial metabolite mimicry Z Dvořák, F Kopp, CM Costello, JS Kemp, H Li, A Vrzalová, M Štěpánková, ... EMBO molecular medicine 12 (4), e11621, 2020 | 64 | 2020 |
| Proresolution effects of hydrogen sulfide during colitis are mediated through hypoxia‐inducible factor‐1α KL Flannigan, TA Agbor, JP Motta, JGP Ferraz, R Wang, AG Buret, ... The FASEB Journal 29 (4), 1591-1602, 2015 | 64 | 2015 |
| Enhanced chemopreventive effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer W Elsheikh, RW Blackler, KL Flannigan, JL Wallace Nitric Oxide 41, 131-137, 2014 | 63 | 2014 |
| Harnessing regulatory T cells for the treatment of inflammatory bowel disease D Geem, A Harusato, K Flannigan, TL Denning Inflammatory bowel diseases 21 (6), 1409-1418, 2015 | 52 | 2015 |
| The pregnane X receptor and indole-3-propionic acid shape the intestinal mesenchyme to restrain inflammation and fibrosis KL Flannigan, KM Nieves, HE Szczepanski, A Serra, JW Lee, LA Alston, ... Cellular and molecular gastroenterology and hepatology 15 (3), 765-795, 2023 | 49 | 2023 |
| Constitutive androstane receptor regulates the intestinal mucosal response to injury GM Hudson, KL Flannigan, SL Erickson, FA Vicentini, A Zamponi, ... British journal of pharmacology 174 (12), 1857-1871, 2017 | 43 | 2017 |
| Xenobiotic receptor-mediated regulation of intestinal barrier function and innate immunity HS Ranhotra, KL Flannigan, M Brave, S Mukherjee, DJ Lukin, SA Hirota, ... Nuclear receptor research 3, 101199, 2016 | 38 | 2016 |
Simon HirotaProfessor, Dept. of Physiology & Pharmacology, University of Calgaryایمیل تأیید شده در ucalgary.ca