| Site-specific introduction of an acetyl-lysine mimic into peptides and proteins by cysteine alkylation R Huang, MA Holbert, MK Tarrant, S Curtet, DR Colquhoun, BM Dancy, ... Journal of the American Chemical Society 132 (29), 9986-9987, 2010 | 134 | 2010 |
| A selective phenelzine analogue inhibitor of histone demethylase LSD1 P Prusevich, JH Kalin, SA Ming, M Basso, J Givens, X Li, J Hu, MS Taylor, ... ACS chemical biology 9 (6), 1284-1293, 2014 | 118 | 2014 |
| The role of epigenomics in personalized medicine MM Kronfol, MG Dozmorov, R Huang, PW Slattum, JL McClay Expert review of precision medicine and drug development 2 (1), 33-45, 2017 | 88 | 2017 |
| Design, synthesis, and kinetic analysis of potent protein N-terminal methyltransferase 1 inhibitors G Zhang, SL Richardson, Y Mao, R Huang Organic & biomolecular chemistry 13 (14), 4149-4154, 2015 | 65 | 2015 |
| Non-histone arginine methylation by protein arginine methyltransferases AA Al-Hamashi, K Diaz, R Huang Current Protein and Peptide Science 21 (7), 699-712, 2020 | 51 | 2020 |
| Structural basis for substrate recognition by the human N-terminal methyltransferase 1 C Dong, Y Mao, W Tempel, S Qin, L Li, P Loppnau, R Huang, J Min Genes & Development 29 (22), 2343-2348, 2015 | 50 | 2015 |
| Kinetic mechanism of protein N-terminal methyltransferase 1 SL Richardson, Y Mao, G Zhang, P Hanjra, DL Peterson, R Huang Journal of Biological Chemistry 290 (18), 11601-11610, 2015 | 48 | 2015 |
| Novel Propargyl-Linked Bisubstrate Analogues as Tight-Binding Inhibitors for Nicotinamide N-Methyltransferase D Chen, L Li, K Diaz, ID Iyamu, R Yadav, N Noinaj, R Huang Journal of medicinal chemistry 62 (23), 10783-10797, 2019 | 44 | 2019 |
| Acetylation of lysine 92 improves the chaperone and anti-apoptotic activities of human αB-crystallin RB Nahomi, R Huang, SK Nandi, B Wang, S Padmanabha, ... Biochemistry 52 (45), 8126-8138, 2013 | 36 | 2013 |
| Discovery of bisubstrate inhibitors for protein N-terminal methyltransferase 1 D Chen, G Dong, N Noinaj, R Huang Journal of medicinal chemistry 62 (7), 3773-3779, 2019 | 27 | 2019 |
| Chemical Biology of Protein N‐Terminal Methyltransferases R Huang ChemBioChem 20 (8), 976-984, 2019 | 24 | 2019 |
| Probing the plasticity in the active site of protein N-terminal methyltransferase 1 using bisubstrate analogues D Chen, C Dong, G Dong, K Srinivasan, J Min, N Noinaj, R Huang Journal of medicinal chemistry 63 (15), 8419-8431, 2020 | 23 | 2020 |
| An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2 C Dong, G Dong, L Li, L Zhu, W Tempel, Y Liu, R Huang, J Min Communications Biology 1 (1), 183, 2018 | 23 | 2018 |
| Discovery of a potent and dual-selective bisubstrate inhibitor for protein arginine methyltransferase 4/5 AA Al-Hamashi, D Chen, Y Deng, G Dong, R Huang Acta Pharmaceutica Sinica B 11 (9), 2709-2718, 2021 | 22 | 2021 |
| Past, present, and perspectives of protein N-terminal methylation K Diaz, Y Meng, R Huang Current opinion in chemical biology 63, 115-122, 2021 | 22 | 2021 |
| A direct, ratiometric, and quantitative MALDI–MS assay for protein methyltransferases and acetyltransferases SL Richardson, P Hanjra, G Zhang, BD Mackie, DL Peterson, R Huang Analytical biochemistry 478, 59-64, 2015 | 22 | 2015 |
| MassSQUIRM: An assay for quantitative measurement of lysine demethylase activity LP Blair, NL Avaritt, R Huang, PA Cole, SD Taverna, AJ Tackett Epigenetics 6 (4), 490-499, 2011 | 21 | 2011 |
| Facile synthesis of SAM–peptide conjugates through alkyl linkers targeting protein N-terminal methyltransferase 1 G Zhang, R Huang RSC advances 6 (8), 6768-6771, 2016 | 20 | 2016 |
| Development of fluorescence polarization-based competition assay for nicotinamide N-methyltransferase ID Iyamu, R Huang Analytical biochemistry 604, 113833, 2020 | 18 | 2020 |
| A pan-inhibitor for protein arginine methyltransferase family enzymes ID Iyamu, AA Al-Hamashi, R Huang Biomolecules 11 (6), 854, 2021 | 17 | 2021 |
