Glutathione primes T cell metabolism for inflammation TW Mak, M Grusdat, GS Duncan, C Dostert, Y Nonnenmacher, M Cox, ... Immunity 46 (4), 675-689, 2017 | 499 | 2017 |
The TNF family of ligands and receptors: communication modules in the immune system and beyond C Dostert, M Grusdat, E Letellier, D Brenner Physiological reviews 99 (1), 115-160, 2019 | 441 | 2019 |
Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity PA Lang, KS Lang, HC Xu, M Grusdat, IA Parish, M Recher, AR Elford, ... Proceedings of the National Academy of Sciences 109 (4), 1210-1215, 2012 | 380 | 2012 |
Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus N Honke, N Shaabani, G Cadeddu, UR Sorg, DE Zhang, M Trilling, ... Nature immunology 13 (1), 51-57, 2012 | 261 | 2012 |
Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity HC Xu, M Grusdat, AA Pandyra, R Polz, J Huang, P Sharma, R Deenen, ... Immunity 40 (6), 949-960, 2014 | 256 | 2014 |
Glutathione restricts serine metabolism to preserve regulatory T cell function H Kurniawan, DG Franchina, L Guerra, L Bonetti, L Soriano-Baguet, ... Cell metabolism 31 (5), 920-936. e7, 2020 | 160 | 2020 |
The transcription factor Interferon Regulatory Factor 4 is required for the generation of protective effector CD8+ T cells F Raczkowski, J Ritter, K Heesch, V Schumacher, A Guralnik, L Höcker, ... Proceedings of the National Academy of Sciences 110 (37), 15019-15024, 2013 | 120 | 2013 |
IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis C Lückel, F Picard, H Raifer, L Campos Carrascosa, A Guralnik, Y Zhang, ... Nature communications 10 (1), 5722, 2019 | 102 | 2019 |
IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV M Grusdat, DR McIlwain, HC Xu, VI Pozdeev, J Knievel, SQ Crome, ... Cell Death & Differentiation 21 (7), 1050-1060, 2014 | 89 | 2014 |
B-cell metabolic remodeling and cancer DG Franchina, M Grusdat, D Brenner Trends in cancer 4 (2), 138-150, 2018 | 76 | 2018 |
Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages W He, A Henne, M Lauterbach, E Geißmar, F Nikolka, C Kho, A Heinz, ... Nature metabolism 4 (5), 524-533, 2022 | 65 | 2022 |
Reactive oxygen species delay control of lymphocytic choriomeningitis virus PA Lang, HC Xu, M Grusdat, DR McIlwain, AA Pandyra, IS Harris, ... Cell Death & Differentiation 20 (4), 649-658, 2013 | 52 | 2013 |
PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis during ageing E Danileviciute, N Zeng, CM Capelle, N Paczia, MA Gillespie, ... Nature metabolism 4 (5), 589-607, 2022 | 38 | 2022 |
Deficiency of the B Cell-Activating Factor Receptor Results in Limited CD169+ Macrophage Function during Viral Infection HC Xu, J Huang, V Khairnar, V Duhan, AA Pandyra, M Grusdat, P Shinde, ... Journal of virology 89 (9), 4748-4759, 2015 | 35 | 2015 |
Recombinant p35 from bacteria can form Interleukin (IL-) 12, but Not IL-35 S Aparicio-Siegmund, JM Moll, J Lokau, M Grusdat, J Schröder, S Plöhn, ... PloS one 9 (9), e107990, 2014 | 31 | 2014 |
NK Cells Regulate CD8+ T Cell Mediated Autoimmunity PA Lang, SQ Crome, HC Xu, KS Lang, L Chapatte, EK Deenick, ... Frontiers in cellular and infection microbiology 10, 36, 2020 | 30 | 2020 |
Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells DG Franchina, H Kurniawan, M Grusdat, C Binsfeld, L Guerra, L Bonetti, ... Nature Communications 13 (1), 1789, 2022 | 27 | 2022 |
T‐cell STAT3 is required for the maintenance of humoral immunity to LCMV DR McIlwain, M Grusdat, VI Pozdeev, HC Xu, P Shinde, C Reardon, ... European journal of immunology 45 (2), 418-427, 2015 | 26 | 2015 |
Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions L Soriano-Baguet, M Grusdat, H Kurniawan, M Benzarti, C Binsfeld, ... Cell Reports 42 (3), 2023 | 18 | 2023 |
A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation L Bonetti, V Horkova, M Grusdat, J Longworth, L Guerra, H Kurniawan, ... Cell Metabolism 36 (8), 1726-1744. e10, 2024 | 9 | 2024 |