A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity Z Ahmed, J Cooper, TK Murray, K Garn, E McNaughton, H Clarke, ... Acta neuropathologica 127, 667-683, 2014 | 537 | 2014 |
Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression X Chai, S Wu, TK Murray, R Kinley, CV Cella, H Sims, N Buckner, ... Journal of Biological Chemistry 286 (39), 34457-34467, 2011 | 417 | 2011 |
Impaired glymphatic function and clearance of tau in an Alzheimer’s disease model IF Harrison, O Ismail, A Machhada, N Colgan, Y Ohene, P Nahavandi, ... Brain 143 (8), 2576-2593, 2020 | 399 | 2020 |
6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cδ K Hanrott, L Gudmunsen, MJ O’Neill, S Wonnacott Journal of biological chemistry 281 (9), 5373-5382, 2006 | 326 | 2006 |
Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment G De Foubert, SL Carney, CS Robinson, EJ Destexhe, R Tomlinson, ... Neuroscience 128 (3), 597-604, 2004 | 300 | 2004 |
Conformation determines the seeding potencies of native and recombinant Tau aggregates B Falcon, A Cavallini, R Angers, S Glover, TK Murray, L Barnham, ... Journal of biological chemistry 290 (2), 1049-1065, 2015 | 297 | 2015 |
AMPA receptor potentiators for the treatment of CNS disorders MJ O'Neill, D Bleakman, DM Zimmerman, ES Nisenbaum Current Drug Targets-CNS & Neurological Disorders 3 (3), 181-194, 2004 | 286 | 2004 |
The role of neuronal nicotinic acetylcholine receptors in acute and chronic neurodegeneration MJ O'neill, TK Murray, V Lakics, NP Visanji, S Duty Current Drug Targets-CNS & Neurological Disorders 1 (4), 399-411, 2002 | 275 | 2002 |
Application of neurite orientation dispersion and density imaging (NODDI) to a tau pathology model of Alzheimer's disease N Colgan, B Siow, JM O'Callaghan, IF Harrison, JA Wells, HE Holmes, ... Neuroimage 125, 739-744, 2016 | 234 | 2016 |
A common mucosal immunologic system involving the bronchus, breast and bowel J Bienenstock, M McDermott, D Befus, M O’Neill Secretory Immunity and Infection: Proceedings of the International Symposium …, 1978 | 225 | 1978 |
Antagonists of GLUK5-containing kainate receptors prevent pilocarpine-induced limbic seizures I Smolders, ZA Bortolotto, VRJ Clarke, R Warre, GM Khan, MJ O'neill, ... Nature neuroscience 5 (8), 796-804, 2002 | 185 | 2002 |
Cytotoxic activities of gut mucosal lymphoid cells in guinea pigs F Arnaud-Battandier, BM Bundy, M O'Neill, J Bienenstock, DL Nelson The Journal of Immunology 121 (3), 1059-1065, 1978 | 167 | 1978 |
The IMPROVE guidelines (ischaemia models: procedural refinements of in vivo experiments) N Percie du Sert, A Alfieri, SM Allan, HVO Carswell, GA Deuchar, TD Farr, ... Journal of Cerebral Blood Flow & Metabolism 37 (11), 3488-3517, 2017 | 165 | 2017 |
Short fibrils constitute the major species of seed-competent tau in the brains of mice transgenic for human P301S tau SJ Jackson, C Kerridge, J Cooper, A Cavallini, B Falcon, CV Cella, ... Journal of Neuroscience 36 (3), 762-772, 2016 | 163 | 2016 |
An AMPA receptor potentiator modulates hippocampal expression of BDNF: an in vivo study M Mackowiak, MJ O’Neill, CA Hicks, D Bleakman, P Skolnick Neuropharmacology 43 (1), 1-10, 2002 | 162 | 2002 |
Loss of microRNA-7 regulation leads to α-synuclein accumulation and dopaminergic neuronal loss in vivo KJ McMillan, TK Murray, N Bengoa-Vergniory, O Cordero-Llana, J Cooper, ... Molecular Therapy 25 (10), 2404-2414, 2017 | 149 | 2017 |
Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist,(+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366 … V Bruno, G Battaglia, A Kingston, MJ O’neill, MV Catania, R Di Grezia, ... Neuropharmacology 38 (2), 199-207, 1999 | 145 | 1999 |
The adenosine A2A antagonist KF17837 reverses the locomotor suppression and tremulous jaw movements induced by haloperidol in rats: possible relevance to parkinsonism M Correa, A Wisniecki, A Betz, DR Dobson, MF O’Neill, MJ O’Neill, ... Behavioural Brain Research 148 (1-2), 47-54, 2004 | 144 | 2004 |
Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer’s disease brain K Kurbatskaya, EC Phillips, CL Croft, G Dentoni, MM Hughes, MA Wade, ... Acta neuropathologica communications 4, 1-15, 2016 | 141 | 2016 |
Decahydroisoquinolines: novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia MJ O'Neill, A Bond, PL Ornstein, MA Ward, CA Hicks, K Hoo, D Bleakman, ... Neuropharmacology 37 (10-11), 1211-1222, 1998 | 140 | 1998 |