دنبال کردن
Nicole Kleinstreuer
Nicole Kleinstreuer
NICEATM Director
ایمیل تأیید شده در nih.gov
عنوان
نقل شده توسط
نقل شده توسط
سال
Chronic inflammation in the etiology of disease across the life span
D Furman, J Campisi, E Verdin, P Carrera-Bastos, S Targ, C Franceschi, ...
Nature medicine 25 (12), 1822-1832, 2019
39522019
Update on EPA’s ToxCast program: providing high throughput decision support tools for chemical risk management
R Kavlock, K Chandler, K Houck, S Hunter, R Judson, N Kleinstreuer, ...
Chemical research in toxicology 25 (7), 1287-1302, 2012
5122012
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ...
Carcinogenesis 36 (Suppl_1), S254-S296, 2015
3612015
Zebrafish developmental screening of the ToxCast™ Phase I chemical library
S Padilla, D Corum, B Padnos, DL Hunter, A Beam, KA Houck, N Sipes, ...
Reproductive toxicology 33 (2), 174-187, 2012
3452012
Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space
R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ...
Toxicological Sciences 152 (2), 323-339, 2016
2802016
Screening chemicals for estrogen receptor bioactivity using a computational model
P Browne, RS Judson, WM Casey, NC Kleinstreuer, RS Thomas
Environmental science & technology 49 (14), 8804-8814, 2015
2732015
In vitro to in vivo extrapolation for high throughput prioritization and decision making
SM Bell, X Chang, JF Wambaugh, DG Allen, M Bartels, KLR Brouwer, ...
Toxicology in vitro 47, 213-227, 2018
2402018
T4 report: Toward good read-across practice (GRAP) guidance
N Ball, MTD Cronin, J Shen, K Blackburn, ED Booth, M Bouhifd, E Donley, ...
Altex 33 (2), 149, 2016
2102016
Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data
NS Sipes, MT Martin, DM Reif, NC Kleinstreuer, RS Judson, AV Singh, ...
Toxicological Sciences 124 (1), 109-127, 2011
2102011
Development and validation of a computational model for androgen receptor activity
NC Kleinstreuer, P Ceger, ED Watt, M Martin, K Houck, P Browne, ...
Chemical research in toxicology 30 (4), 946-964, 2017
2042017
Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms
NC Kleinstreuer, J Yang, EL Berg, TB Knudsen, AM Richard, MT Martin, ...
Nature biotechnology 32 (6), 583-591, 2014
2022014
Non-animal methods to predict skin sensitization (II): an assessment of defined approaches
NC Kleinstreuer, S Hoffmann, N Alépée, D Allen, T Ashikaga, W Casey, ...
Critical reviews in toxicology 48 (5), 359-374, 2018
1892018
Integrated Testing Strategies (ITS) for safety assessment.
C Rovida, N Alépée, AM Api, DA Basketter, F y Bois, F Caloni, E Corsini, ...
ALTEX-Alternatives to Animal Experimentations 32 (1), 25-40, 2015
1882015
In silico prediction of physicochemical properties of environmental chemicals using molecular fingerprints and machine learning
Q Zang, K Mansouri, AJ Williams, RS Judson, DG Allen, WM Casey, ...
Journal of chemical information and modeling 57 (1), 36-49, 2017
1812017
CoMPARA: collaborative modeling project for androgen receptor activity
K Mansouri, N Kleinstreuer, AM Abdelaziz, D Alberga, VM Alves, ...
Environmental Health Perspectives 128 (2), 027002, 2020
1712020
Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database
S Hoffmann, N Kleinstreuer, N Alépée, D Allen, AM Api, T Ashikaga, ...
Critical reviews in toxicology 48 (5), 344-358, 2018
1692018
An evaluation framework for new approach methodologies (NAMs) for human health safety assessment
ST Parish, M Aschner, W Casey, M Corvaro, MR Embry, S Fitzpatrick, ...
Regulatory Toxicology and Pharmacology 112, 104592, 2020
1672020
Open-source QSAR models for pKa prediction using multiple machine learning approaches
K Mansouri, NF Cariello, A Korotcov, V Tkachenko, CM Grulke, ...
Journal of Cheminformatics 11, 1-20, 2019
1572019
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets
TB Knudsen, KA Houck, NS Sipes, AV Singh, RS Judson, MT Martin, ...
Toxicology 282 (1-2), 1-15, 2011
1572011
SAR and QSAR modeling of a large collection of LD50 rat acute oral toxicity data
D Gadaleta, K Vuković, C Toma, GJ Lavado, AL Karmaus, K Mansouri, ...
Journal of Cheminformatics 11, 1-16, 2019
1492019
سیستم در حال حاضر قادر به انجام عملکرد نیست. بعداً دوباره امتحان کنید.
مقاله‌ها 1–20