Mesenchymal stem cells enhance recovery and repair following ventilator-induced lung injury in the rat GF Curley, M Hayes, B Ansari, G Shaw, A Ryan, F Barry, T O'Brien, ... Thorax 67 (6), 496-501, 2012 | 341 | 2012 |
Human mesenchymal stromal cells decrease the severity of acute lung injury induced by E. coli in the rat J Devaney, S Horie, C Masterson, S Elliman, F Barry, T O'Brien, GF Curley, ... Thorax 70 (7), 625-635, 2015 | 243 | 2015 |
β-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in-vitro immunomodulatory and pulmonary cytoprotective effects—Implications for … EJ Murphy, C Masterson, E Rezoagli, D O'Toole, I Major, GD Stack, ... Science of the Total Environment 732, 139330, 2020 | 184 | 2020 |
Effects of intratracheal mesenchymal stromal cell therapy during recovery and resolution after ventilator-induced lung injury GF Curley, B Ansari, M Hayes, J Devaney, C Masterson, A Ryan, F Barry, ... Anesthesiology 118 (4), 924-32, 2013 | 146 | 2013 |
Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia L McGinley, J McMahon, P Strappe, F Barry, M Murphy, D O'Toole, ... Stem cell research & therapy 2, 1-18, 2011 | 145 | 2011 |
Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-κB dependent mechanism D O’Toole, P Hassett, M Contreras, BD Higgins, STW McKeown, ... Thorax 64 (11), 976-982, 2009 | 145 | 2009 |
Mesenchymal stem cell survival in the infarcted heart is enhanced by lentivirus vector-mediated heat shock protein 27 expression LM McGinley, J McMahon, A Stocca, A Duffy, A Flynn, D O'Toole, ... Human gene therapy 24 (10), 840-851, 2013 | 127 | 2013 |
Hypercapnic acidosis attenuates ventilation-induced lung injury by a nuclear factor-κB–dependent mechanism M Contreras, B Ansari, G Curley, BD Higgins, P Hassett, D O’Toole, ... Critical care medicine 40 (9), 2622-2630, 2012 | 118 | 2012 |
Hypercapnic acidosis attenuates shock and lung injury in early and prolonged systemic sepsis J Costello, B Higgins, M Contreras, MN Chonghaile, P Hassett, D O'Toole, ... Critical care medicine 37 (8), 2412-2420, 2009 | 107 | 2009 |
Cryopreserved, xeno-free human umbilical cord mesenchymal stromal cells reduce lung injury severity and bacterial burden in rodent Escherichia coli–induced acute respiratory … GF Curley, M Jerkic, S Dixon, G Hogan, C Masterson, D O’Toole, ... Critical care medicine 45 (2), e202-e212, 2017 | 98 | 2017 |
Mesenchymal stromal cells are more effective than the MSC secretome in diminishing injury and enhancing recovery following ventilator-induced lung injury M Hayes, GF Curley, C Masterson, J Devaney, D O’Toole, JG Laffey Intensive care medicine experimental 3, 1-14, 2015 | 95 | 2015 |
Therapeutic efficacy of human mesenchymal stromal cells in the repair of established ventilator-induced lung injury in the rat M Hayes, C Masterson, J Devaney, F Barry, S Elliman, T O’Brien, ... Survey of Anesthesiology 59 (6), 259-260, 2015 | 85 | 2015 |
The synthetic cannabinoid R (+) WIN 55,212-2 inhibits the interleukin-1 signaling pathway in human astrocytes in a cannabinoid receptor-independent manner NM Curran, BD Griffin, D O'Toole, KJ Brady, SN Fitzgerald, PN Moynagh Journal of Biological Chemistry 280 (43), 35797-35806, 2005 | 83 | 2005 |
Myosin Light Chain Kinase Inhibition: Correction of Increased Intestinal Epithelial Permeability In Vitro LM Feighery, SW Cochrane, T Quinn, AW Baird, D O’Toole, SE Owens, ... Pharmaceutical research 25, 1377-1386, 2008 | 75 | 2008 |
Differential effects of buffered hypercapnia versus hypercapnic acidosis on shock and lung injury induced by systemic sepsis BD Higgins, J Costello, M Contreras, P Hassett, D O'Toole, JG Laffey Anesthesiology 111 (6), 1317-1326, 2009 | 72 | 2009 |
Infection-induced lung injury is worsened after renal buffering of hypercapnic acidosis AD Nichol, DF O'Cronin, K Howell, F Naughton, S O'Brien, J Boylan, ... Critical care medicine 37 (11), 2953-2961, 2009 | 64 | 2009 |
Syndecan-2-positive, Bone Marrow-derived Human Mesenchymal Stromal Cells Attenuate Bacterial-induced Acute Lung Injury and Enhance Resolution of Ventilator-induced Lung Injury … C Masterson, J Devaney, S Horie, L O'Flynn, L Deedigan, S Elliman, ... Anesthesiology 129 (3), 502-516, 2018 | 63 | 2018 |
Human mesenchymal stem cell secretome from bone marrow or adipose-derived tissue sources for treatment of hypoxia-induced pulmonary epithelial injury N Shologu, M Scully, JG Laffey, D O’Toole International journal of molecular sciences 19 (10), 2996, 2018 | 60 | 2018 |
Effects and mechanisms of action of sildenafil citrate in human chorionic arteries CH Maharaj, D O'Toole, T Lynch, J Carney, J Jarman, BD Higgins, ... Reproductive Biology and Endocrinology 7, 1-10, 2009 | 59 | 2009 |
Evolution of the inflammatory and fibroproliferative responses during resolution and repair after ventilator-induced lung injury in the rat GF Curley, M Contreras, B Higgins, C O'Kane, DF McAuley, D O'Toole, ... Anesthesiology 115 (5), 1022-1032, 2011 | 58 | 2011 |