| Thieno [2, 3-d] pyrimidine as a promising scaffold in medicinal chemistry: Recent advances EMH Ali, MS Abdel-Maksoud, CH Oh Bioorganic & medicinal chemistry 27 (7), 1159-1194, 2019 | 105 | 2019 |
| Pyrazolo [3, 4-d] pyrimidine based scaffold derivatives targeting kinases as anticancer agents NSM Ismail, EMH Ali, DA Ibrahim, RAT Serya, DA Abou El Ella Future Journal of Pharmaceutical Sciences 2 (1), 20-30, 2016 | 60 | 2016 |
| Design, synthesis, and biological evaluation of novel imidazole derivatives possessing terminal sulphonamides as potential BRAFV600Eáinhibitors EMH Ali, MS Abdel-Maksoud, UM Ammar, KI Mersal, KH Yoo, ... Bioorganic Chemistry 106, 104508, 2021 | 33 | 2021 |
| Design, synthesis and anti-inflammatory activity of imidazol-5-yl pyridine derivatives as p38α/MAPK14 inhibitor EMH Ali, MS Abdel-Maksoud, RM Hassan, KI Mersal, UM Ammar, C Se-In, ... Bioorganic & Medicinal Chemistry 31, 115969, 2021 | 30 | 2021 |
| Design, synthesis, and anticancer activity of imidazo [2, 1-b] oxazole-based RAF kinase inhibitors MS Abdel-Maksoud, UM Ammar, MI El-Gamal, MMG El-Din, KI Mersal, ... Bioorganic Chemistry 93, 103349, 2019 | 27 | 2019 |
| Discovery of New Imidazo[2,1-b]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising In Vitro and In Vivo Anti-melanoma Activity MS Abdel-Maksoud, MI El-Gamal, BS Lee, MM Gamal El-Din, HR Jeon, ... Journal of Medicinal Chemistry 64 (10), 6877-6901, 2021 | 25 | 2021 |
| New horizons in drug discovery of lymphocyte-specific protein tyrosine kinase (Lck) inhibitors: A decade review (2011–2021) focussing on structure–activity relationship (SAR … A Elkamhawy, EMH Ali, K Lee Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1572-1600, 2021 | 22 | 2021 |
| Structural optimization of imidazothiazole derivatives affords a new promising series as B-Raf V600E inhibitors; synthesis, in vitro assay and in silico screening UM Ammar, MS Abdel-Maksoud, EMH Ali, KI Mersal, KH Yoo, CH Oh Bioorganic Chemistry 100, 103967, 2020 | 22 | 2020 |
| Design, synthesis, biological evaluation, and docking studies of novel (imidazol-5-yl) pyrimidine-based derivatives as dual BRAFV600E/p38α inhibitors EMH Ali, RFA El-Telbany, MS Abdel-Maksoud, UM Ammar, KI Mersal, ... European Journal of Medicinal Chemistry 215, 113277, 2021 | 20 | 2021 |
| Modification of imidazothiazole derivatives gives promising activity in B-Raf kinase enzyme inhibition; synthesis, in vitro studies and molecular docking UM Ammar, MS Abdel-Maksoud, KI Mersal, EMH Ali, KH Yoo, HS Choi, ... Bioorganic & Medicinal Chemistry Letters 30 (20), 127478, 2020 | 15 | 2020 |
| Design and synthesis of novel pyrrolo [2, 3-b] pyridine derivatives targeting V600EBRAF MS Abdel-Maksoud, EMH Ali, UM Ammar, KI Mersal, KH Yoo, CH Oh Bioorganic & Medicinal Chemistry 28 (11), 115493, 2020 | 14 | 2020 |
| Structural optimization of 4-(imidazol-5-yl) pyridine derivatives affords broad-spectrum anticancer agents with selective B-RAFV600E/p38α kinase inhibitory activity: synthesis … EMH Ali, KI Mersal, UM Ammar, SO Zaraei, MS Abdel-Maksoud, ... European Journal of Pharmaceutical Sciences 171, 106115, 2022 | 13 | 2022 |
| Ligand-based design, molecular dynamics and ADMET studies of suggested SARS-CoV-2 M pro inhibitors NM Mohamed, EMH Ali, AM AboulMagd RSC advances 11 (8), 4523-4538, 2021 | 10 | 2021 |
| Identification of novel aryl carboxamide derivatives as death-associated protein kinase 1 (DAPK1) inhibitors with anti-proliferative activities: design, synthesis, in vitro … A Elkamhawy, S Paik, EMH Ali, AHE Hassan, SJ Kang, K Lee, EJ Roh Pharmaceuticals 15 (9), 1050, 2022 | 7 | 2022 |
| Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cells KI Mersal, MS Abdel-Maksoud, EMH Ali, UM Ammar, SO Zaraei, ... European Journal of Medicinal Chemistry 261, 115779, 2023 | 6 | 2023 |
| ByeTAC: bypassing an E3 ligase for targeted protein degradation EMH Ali, CA Loy, DJ Trader BioRxiv, 2024.01. 20.576376, 2024 | 5 | 2024 |
| Design, synthesis, in vitro determination and molecular docking studies of 4-(1-(tert-butyl)-3-phenyl-1H-pyrazol-4-yl) pyridine derivatives with terminal sulfonamide … KI Mersal, MS Abdel-Maksoud, EMH Ali, UM Ammar, SO Zaraei, JM Kim, ... Medicinal Chemistry Research 30 (10), 1925-1942, 2021 | 4 | 2021 |
| Discovery of a non-covalent ligand for Rpn-13, a therapeutic target for hematological cancers CA Loy, CS Muli, EMH Ali, D Xie, MH Ahmed, CB Post, DJ Trader Bioorganic & Medicinal Chemistry Letters 95, 129485, 2023 | 3 | 2023 |
| Discovery of potential RAF-selective back pocket as a promising biological target for BRAF inhibitors in the treatment of resistant melanoma: Design, synthesis, biological … U Ammar, M Gamal, M Abdel-Maksoud, E Ali, Z Mahmoud, K Deug, P Jun, ... Cancer Research 84 (6_Supplement), 2024 | | 2024 |