Synergistic effects of common schizophrenia risk variants N Schrode, SM Ho, K Yamamuro, A Dobbyn, L Huckins, MR Matos, ... Nature genetics 51 (10), 1475-1485, 2019 | 231 | 2019 |
Neuronal impact of patient-specific aberrant NRXN1α splicing E Flaherty, S Zhu, N Barretto, E Cheng, PJM Deans, MB Fernando, ... Nature genetics 51 (12), 1679-1690, 2019 | 121 | 2019 |
Signature-based approaches for informed drug repurposing: targeting CNS disorders R Shukla, ND Henkel, K Alganem, A Hamoud, J Reigle, RS Alnafisah, ... Neuropsychopharmacology 46 (1), 116-130, 2021 | 56 | 2021 |
Connectivity analyses of bioenergetic changes in schizophrenia: identification of novel treatments CR Sullivan, CA Mielnik, SM O’Donovan, AJ Funk, E Bentea, ... Molecular neurobiology 56, 4492-4517, 2019 | 47 | 2019 |
Kinome array profiling of patient-derived pancreatic ductal adenocarcinoma identifies differentially active protein tyrosine kinases JF Creeden, K Alganem, AS Imami, FC Brunicardi, SH Liu, R Shukla, ... International journal of molecular sciences 21 (22), 8679, 2020 | 37 | 2020 |
Hepatic kinome atlas: an in‐depth identification of kinase pathways in liver fibrosis of humans and rodents JF Creeden, ZA Kipp, M Xu, RM Flight, HNB Moseley, GJ Martinez, ... Hepatology 76 (5), 1376-1388, 2022 | 36 | 2022 |
mTOR kinase activity disrupts a phosphorylation signaling network in schizophrenia brain R Chadha, K Alganem, RE Mccullumsmith, JH Meador-Woodruff Molecular psychiatry 26 (11), 6868-6879, 2021 | 31 | 2021 |
The active kinome: The modern view of how active protein kinase networks fit in biological research K Alganem, AR Hamoud, JF Creeden, ND Henkel, AS Imami, AW Joyce, ... Current opinion in pharmacology 62, 117-129, 2022 | 21 | 2022 |
Antipsychotics impair regulation of glucose metabolism by central glucose LN Castellani, S Pereira, C Kowalchuk, R Asgariroozbehani, R Singh, ... Molecular Psychiatry 27 (11), 4741-4753, 2022 | 19 | 2022 |
Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity X Wu, R Shukla, K Alganem, X Zhang, HM Eby, EA Devine, E Depasquale, ... Molecular psychiatry 26 (12), 7699-7708, 2021 | 19 | 2021 |
KRSA: An R package and R Shiny web application for an end-to-end upstream kinase analysis of kinome array data EAK DePasquale, K Alganem, E Bentea, N Nawreen, JL McGuire, ... PloS one 16 (12), e0260440, 2021 | 17 | 2021 |
Microcystin-LR (MC-LR) triggers inflammatory responses in macrophages RC Su, JD Breidenbach, K Alganem, FK Khalaf, BW French, P Dube, ... International journal of molecular sciences 22 (18), 9939, 2021 | 17 | 2021 |
Kaleidoscope: a new bioinformatics pipeline web application for in silico hypothesis exploration of omics signatures K Alganem, R Shukla, H Eby, M Abel, X Zhang, WB McIntyre, J Lee, ... bioRxiv, 2020.05. 01.070805, 2020 | 17 | 2020 |
Emerging kinase therapeutic targets in pancreatic ductal adenocarcinoma and pancreatic cancer desmoplasia JF Creeden, K Alganem, AS Imami, ND Henkel, FC Brunicardi, SH Liu, ... International Journal of Molecular Sciences 21 (22), 8823, 2020 | 16 | 2020 |
KRSA: Network-based prediction of differential kinase activity from kinome array data EAK DePasquale, K Alganem, E Bentea, N Nawreen, JL McGuire, F Naji, ... BioRxiv, 2020.08. 26.268581, 2020 | 13 | 2020 |
Protein expression of prenyltransferase subunits in postmortem schizophrenia dorsolateral prefrontal cortex AL Pinner, TM Mueller, K Alganem, R McCullumsmith, ... Translational psychiatry 10 (1), 3, 2020 | 13 | 2020 |
Identification of activity-induced Egr3-dependent genes reveals genes associated with DNA damage response and schizophrenia KK Marballi, K Alganem, SJ Brunwasser, A Barkatullah, KT Meyers, ... Translational psychiatry 12 (1), 320, 2022 | 12 | 2022 |
Molecular neurobiology of loss: A role for basolateral amygdala extracellular matrix MA Smail, BL Smith, R Shukla, K Alganem, HM Eby, JL Bollinger, ... Molecular Psychiatry 28 (11), 4729-4741, 2023 | 9 | 2023 |
A bioinformatic inquiry of the EAAT2 interactome in postmortem and neuropsychiatric datasets S Asah, K Alganem, RE McCullumsmith, SM O'Donovan Schizophrenia research 249, 38-46, 2022 | 8 | 2022 |
Subcellular partitioning of protein kinase activity revealed by functional kinome profiling L Wegman-Points, K Alganem, AS Imami, V Mathis, JF Creeden, ... Scientific Reports 12 (1), 17300, 2022 | 6 | 2022 |