Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, L Pache, ... Nature 586 (7827), 113-119, 2020 | 789 | 2020 |
Identification of bacteria-derived HLA-bound peptides in melanoma S Kalaora, A Nagler, D Nejman, M Alon, C Barbolin, E Barnea, ... Nature 592 (7852), 138-143, 2021 | 312 | 2021 |
Harnessing synthetic lethality to predict the response to cancer treatment JS Lee, A Das, L Jerby-Arnon, R Arafeh, N Auslander, M Davidson, ... Nature communications 9 (1), 2546, 2018 | 136 | 2018 |
Novel mechanisms for superoxide-scavenging activity of human manganese superoxide dismutase determined by the K68 key acetylation site J Lu, K Cheng, B Zhang, H Xu, Y Cao, F Guo, X Feng, Q Xia Free Radical Biology and Medicine 85, 114-126, 2015 | 60 | 2015 |
In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression S Sinha, K Cheng, AA Schäffer, K Aldape, E Schiff, E Ruppin Molecular systems biology 16 (7), e9628, 2020 | 58 | 2020 |
Identification of drugs associated with reduced severity of COVID-19–a case-control study in a large population A Israel, AA Schäffer, A Cicurel, K Cheng, S Sinha, E Schiff, I Feldhamer, ... Elife 10, e68165, 2021 | 50 | 2021 |
A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing S Sinha, K Barbosa, K Cheng, MDM Leiserson, P Jain, A Deshpande, ... Nature communications 12 (1), 6512, 2021 | 45 | 2021 |
Genome‐scale metabolic modeling reveals SARS‐CoV‐2‐induced metabolic changes and antiviral targets K Cheng, L Martin‐Sancho, LR Pal, Y Pu, L Riva, X Yin, S Sinha, NU Nair, ... Molecular systems biology 17 (11), e10260, 2021 | 40* | 2021 |
Genome‐wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy AD Sahu, J S Lee, Z Wang, G Zhang, R Iglesias‐Bartolome, T Tian, Z Wei, ... Molecular systems biology 15 (3), e8323, 2019 | 34 | 2019 |
Systematic Cell Line-Based Identification of Drugs Modifying ACE2 Expression S Sinha, K Cheng, K Aldape, E Schiff, E Ruppin Preprints, 2020 | 25 | 2020 |
Berberine regulates neurite outgrowth through AMPK-dependent pathways by lowering energy status J Lu, Y Cao, K Cheng, B Xu, T Wang, Q Yang, Q Yang, X Feng, Q Xia Experimental cell research 334 (2), 194-206, 2015 | 24 | 2015 |
Large population study identifies drugs associated with reduced COVID-19 severity A Israel, AA Schäffer, A Cicurel, I Feldhamer, A Tal, K Cheng, S Sinha, ... MedRxiv, 2020 | 18 | 2020 |
Synthetic lethality across normal tissues is strongly associated with cancer risk, onset, and tumor suppressor specificity K Cheng, NU Nair, JS Lee, E Ruppin Science advances 7 (1), eabc2100, 2021 | 17 | 2021 |
Cross-species identification of cancer resistance–associated genes that may mediate human cancer risk NU Nair, K Cheng, L Naddaf, E Sharon, LR Pal, PS Rajagopal, ... Science Advances 8 (31), eabj7176, 2022 | 15 | 2022 |
Combinatorial detection of conserved alteration patterns for identifying cancer subnetworks E Hodzic, R Shrestha, K Zhu, K Cheng, CC Collins, S Cenk Sahinalp GigaScience 8 (4), giz024, 2019 | 9 | 2019 |
MnTM‐4‐PyP modulates endogenous antioxidant responses and protects primary cortical neurons against oxidative stress KY Cheng, F Guo, JQ Lu, YZ Cao, TC Wang, Q Yang, Q Xia CNS Neuroscience & Therapeutics 21 (5), 435-445, 2015 | 8 | 2015 |
Synthetic lethality-based prediction of anti-SARS-CoV-2 targets LR Pal, K Cheng, NU Nair, L Martin-Sancho, S Sinha, Y Pu, L Riva, X Yin, ... Iscience 25 (5), 2022 | 7 | 2022 |
Using a recently approved tumor mutational burden biomarker to stratify patients for immunotherapy may introduce a sex bias N Sinha, S Sinha, K Cheng, S Madan, A Erez, BM Ryan, AA Schäffer, ... JCO precision oncology 5, PO. 21.00168, 2021 | 5 | 2021 |
Integrated computational and experimental identification of p53, KRAS and VHL mutant selection associated with CRISPR-Cas9 editing S Sinha, KB Guerra, K Cheng, MDM Leiserson, DM Wilson III, BM Ryan, ... bioRxiv, 407767, 2018 | 4 | 2018 |
Author Correction: A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing S Sinha, K Barbosa, K Cheng, MDM Leiserson, P Jain, A Deshpande, ... Nature Communications 13, 2828, 2022 | 2 | 2022 |