دنبال کردن
David M. Sabatini
David M. Sabatini
Institute of Organic Chemistry and Biochemistry of the CAS
ایمیل تأیید شده در uochb.cas.cz - صفحهٔ اصلی
عنوان
نقل شده توسط
نقل شده توسط
سال
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1‏
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...‏
autophagy 17 (1), 1-382, 2021‏
13675*2021
mTOR signaling in growth control and disease‏
M Laplante, DM Sabatini‏
cell 149 (2), 274-293, 2012‏
98262012
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex‏
DD Sarbassov, DA Guertin, SM Ali, DM Sabatini‏
Science 307 (5712), 1098-1101, 2005‏
85482005
mTOR signaling in growth, metabolism, and disease‏
RA Saxton, DM Sabatini‏
Cell 168 (6), 960-976, 2017‏
80742017
CellProfiler: image analysis software for identifying and quantifying cell phenotypes‏
AE Carpenter, TR Jones, MR Lamprecht, C Clarke, IH Kang, O Friman, ...‏
Genome biology 7, 1-11, 2006‏
58922006
mTOR: from growth signal integration to cancer, diabetes and ageing‏
R Zoncu, A Efeyan, DM Sabatini‏
Nature reviews Molecular cell biology 12 (1), 21-35, 2011‏
48472011
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery‏
DH Kim, DD Sarbassov, SM Ali, JE King, RR Latek, ...‏
Cell 110 (2), 163-175, 2002‏
38112002
Defining the role of mTOR in cancer‏
DA Guertin, DM Sabatini‏
Cancer cell 12 (1), 9-22, 2007‏
36132007
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton‏
DD Sarbassov, SM Ali, DH Kim, DA Guertin, RR Latek, ...‏
Current biology 14 (14), 1296-1302, 2004‏
34922004
Genetic screens in human cells using the CRISPR-Cas9 system‏
T Wang, JJ Wei, DM Sabatini, ES Lander‏
Science 343 (6166), 80-84, 2014‏
34512014
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1‏
DA Barbie, P Tamayo, JS Boehm, SY Kim, SE Moody, IF Dunn, ...‏
Nature 462 (7269), 108-112, 2009‏
34512009
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB‏
DD Sarbassov, SM Ali, S Sengupta, JH Sheen, PP Hsu, AF Bagley, ...‏
Molecular cell 22 (2), 159-168, 2006‏
33572006
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1‏
Y Sancak, TR Peterson, YD Shaul, RA Lindquist, CC Thoreen, ...‏
Science 320 (5882), 1496-1501, 2008‏
32242008
Cancer cell metabolism: Warburg and beyond‏
PP Hsu, DM Sabatini‏
Cell 134 (5), 703-707, 2008‏
30132008
mTOR signaling at a glance‏
M Laplante, DM Sabatini‏
Journal of cell science 122 (20), 3589-3594, 2009‏
29342009
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids‏
Y Sancak, L Bar-Peled, R Zoncu, AL Markhard, S Nada, DM Sabatini‏
Cell 141 (2), 290-303, 2010‏
27942010
mTOR at the nexus of nutrition, growth, ageing and disease‏
GY Liu, DM Sabatini‏
Nature reviews Molecular cell biology 21 (4), 183-203, 2020‏
22622020
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1‏
CC Thoreen, SA Kang, JW Chang, Q Liu, J Zhang, Y Gao, LJ Reichling, ...‏
Journal of Biological Chemistry 284 (12), 8023-8032, 2009‏
21012009
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen‏
J Moffat, DA Grueneberg, X Yang, SY Kim, AM Kloepfer, G Hinkle, ...‏
Cell 124 (6), 1283-1298, 2006‏
20792006
A lysosome‐to‐nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB‏
C Settembre, R Zoncu, DL Medina, F Vetrini, S Erdin, SU Erdin, T Huynh, ...‏
The EMBO journal 31 (5), 1095-1108, 2012‏
20422012
سیستم در حال حاضر قادر به انجام عملکرد نیست. بعداً دوباره امتحان کنید.
مقاله‌ها 1–20