Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood SR Clark, AC Ma, SA Tavener, B McDonald, Z Goodarzi, MM Kelly, ... Nature medicine 13 (4), 463-469, 2007 | 2667 | 2007 |
Inflammation, innate immunity and blood coagulation J Xu, F Lupu, CT Esmon Hämostaseologie 30 (01), 5-9, 2010 | 261 | 2010 |
Effect of convalescent plasma on organ support–free days in critically ill patients with COVID-19: a randomized clinical trial H Abdelhady, M Abdelrazik, Z Abdi, D Abdo, A Abdulle, L Abel, ... Jama 326 (17), 1690-1702, 2021 | 209 | 2021 |
A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide H Zhou, BM Lapointe, SR Clark, L Zbytnuik, P Kubes The Journal of Immunology 177 (11), 8103-8110, 2006 | 204 | 2006 |
Nitrolinoleate inhibits superoxide generation, degranulation, and integrin expression by human neutrophils: novel antiinflammatory properties of nitric oxide–derived reactive … B Coles, A Bloodsworth, SR Clark, MJ Lewis, AR Cross, BA Freeman, ... Circulation research 91 (5), 375-381, 2002 | 202 | 2002 |
Coronary artery bypass surgery in elderly people A Natarajan, S Samadian, S Clark Postgraduate medical journal 83 (977), 154-158, 2007 | 128 | 2007 |
Cancelled operations: a 7-day cohort study of planned adult inpatient surgery in 245 UK National Health Service hospitals DJN Wong, SK Harris, SR Moonesinghe, SR Moonesinghe, DJN Wong, ... British journal of anaesthesia 121 (4), 730-738, 2018 | 118 | 2018 |
Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection SR Clark, CJ Guy, MJ Scurr, PR Taylor, AP Kift-Morgan, VJ Hammond, ... Blood, The Journal of the American Society of Hematology 117 (6), 2033-2043, 2011 | 106 | 2011 |
Use of CD44 by CD4+ Th1 and Th2 lymphocytes to roll and adhere CS Bonder, SR Clark, MU Norman, P Johnson, P Kubes Blood 107 (12), 4798-4806, 2006 | 106 | 2006 |
Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation SR Clark, CP Thomas, VJ Hammond, M Aldrovandi, GW Wilkinson, ... Proceedings of the National Academy of Sciences 110 (15), 5875-5880, 2013 | 105 | 2013 |
In vivo biocompatibility, clearance, and biodistribution of albumin vehicles for pulmonary drug delivery A Woods, A Patel, D Spina, Y Riffo-Vasquez, A Babin-Morgan, ... Journal of Controlled Release 210, 1-9, 2015 | 100 | 2015 |
Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease AH Morgan, V Dioszeghy, BH Maskrey, CP Thomas, SR Clark, SA Mathie, ... Journal of Biological Chemistry 284 (32), 21185-21191, 2009 | 95 | 2009 |
Combined point-of-care nucleic acid and antibody testing for SARS-CoV-2 following emergence of D614G spike variant P Mlcochova, D Collier, A Ritchie, SM Assennato, M Hosmillo, N Goel, ... Cell Reports Medicine 1 (6), 2020 | 81 | 2020 |
Current smoking predicts increased operative mortality and morbidity after cardiac surgery in the elderly R Jones, B Nyawo, S Jamieson, S Clark Interactive cardiovascular and thoracic surgery 12 (3), 449-453, 2011 | 64 | 2011 |
A second update on mapping the human genetic architecture of COVID-19 M Kanai, SJ Andrews, M Cordioli, C Stevens, BM Neale, M Daly, A Ganna, ... Nature 621 (7977), E7-E26, 2023 | 63 | 2023 |
Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation M Aldrovandi, VJ Hammond, H Podmore, M Hornshaw, SR Clark, ... Journal of lipid research 54 (11), 3085-3097, 2013 | 63 | 2013 |
Use of the surgical Apgar score to guide postoperative care JB Haddow, H Adwan, SE Clark, S Tayeh, SS Antonowicz, P Jayia, ... The Annals of The Royal College of Surgeons of England 96 (5), 352-358, 2014 | 54 | 2014 |
Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity SN Lauder, PR Taylor, SR Clark, RL Evans, JP Hindley, K Smart, H Leach, ... Thorax 66 (5), 368-374, 2011 | 53 | 2011 |
Phase I trial of the heat shock protein 90 (HSP90) inhibitor 17-allylamino 17-demethoxygeldanamycin (17AAG). Pharmacokinetic (PK) profile and pharmacodynamic (PD) endpoints U Banerji, A O’donnell, M Scurr, C Benson, J Hanwell, S Clark, ... Proc Am Soc Clin Oncol 20, 82a, 2001 | 41 | 2001 |
Postoperative critical care and high-acuity care provision in the United Kingdom, Australia, and New Zealand DJN Wong, S Popham, AM Wilson, LM Barneto, HA Lindsay, L Farmer, ... British journal of anaesthesia 122 (4), 460-469, 2019 | 38 | 2019 |