| The evolving role of investigative toxicology in the pharmaceutical industry F Pognan, M Beilmann, H Boonen, A Czich, G Dear, P Hewitt, T Mow, ... Nature reviews drug discovery 22 (4), 317-335, 2023 | 134 | 2023 |
| Optimizing drug discovery by investigative toxicology: current and future trends M Beilmann, H Boonen, A Czich, G Dear, P Hewitt, T Mow, P Newham, ... ALTEX-Alternatives to animal experimentation 36 (2), 289-313, 2019 | 75 | 2019 |
| Force, membrane potential, and [Ca2+] i during activation of rat mesenteric small arteries with norepinephrine, potassium, aluminum fluoride, and phorbol ester. Effects of … PE Jensen, A Hughes, HC Boonen, C Aalkjaer Circulation research 73 (2), 314-324, 1993 | 67 | 1993 |
| Acute and long-term effects of tissue culture on contractile reactivity in renal arteries of the rat. JG De Mey, MP Uitendaal, HC Boonen, MJ Vrijdag, MJ Daemen, ... Circulation research 65 (4), 1125-1135, 1989 | 63 | 1989 |
| 6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-Dioxide Derivatives Potently and Selectively Activate ATP Sensitive Potassium Channels of … FE Nielsen, TB Bodvarsdottir, A Worsaae, P MacKay, CE Stidsen, ... Journal of medicinal chemistry 45 (19), 4171-4187, 2002 | 59 | 2002 |
| Continuous intravenous infusion of deferoxamine reduces mortality by paraquat in vitamin E-deficient rats BS Van Asbeck, FC Hillen, HC Boonen, Y De Jong, JA Dormans, ... Am Rev Respir Dis 139 (3), 769-73, 1989 | 53 | 1989 |
| G-proteins are involved in contractile responses of isolated mesenteric resistance arteries to agonists HCM Boonen, JGR De Mey Naunyn-Schmiedeberg's archives of pharmacology 342, 462-468, 1990 | 49 | 1990 |
| Increased calcium sensitivity in isolated resistance arteries from spontaneously hypertensive rats: effects of dihydropyridines HCM Boonen, JGR De Mey European journal of pharmacology 179 (3), 403-412, 1990 | 48 | 1990 |
| Mesenteric small artery changes after vasoconstrictor infusion in young rats HCM Boonen, MJAP Daemen, PHA Eerdmans, GE Fazzi, EM van Kleef, ... Journal of cardiovascular pharmacology 22 (3), 388-395, 1993 | 43 | 1993 |
| Synthesis and pharmacological evaluation of 4H-1, 4-benzothiazine-2-carbonitrile 1, 1-dioxide and N-(2-cyanomethylsulfonylphenyl) acylamide derivatives as potential activators … SC Schou, HC Hansen, TM Tagmose, HCM Boonen, A Worsaae, ... Bioorganic & medicinal chemistry 13 (1), 141-155, 2005 | 42 | 2005 |
| New 3-alkylamino-4 H-thieno-1, 2, 4-thiadiazine 1, 1-dioxide derivatives activate ATP-sensitive potassium channels of pancreatic beta cells FE Nielsen, S Ebdrup, AF Jensen, L Ynddal, TB Bodvarsdottir, C Stidsen, ... Journal of medicinal chemistry 49 (14), 4127-4139, 2006 | 37 | 2006 |
| Growth responses in isolated elastic, muscular and resistance-sized arterial segments of the rat JGR De Mey, MP Uitendaal, HCM Boonen, PMH Schiffers, GE Fazzi Journal of Vascular Research 28 (5), 372-385, 1991 | 24 | 1991 |
| DNA synthesis in isolated arteries. Kinetics and structural consequences HC Boonen, PM Schiffers, GE Fazzi, GM Janssen, MJ Daemen, ... American Journal of Physiology-Heart and Circulatory Physiology 260 (1 …, 1991 | 24 | 1991 |
| Arylcyanoguanidines as activators of Kir6. 2/SUR1KATP channels and inhibitors of insulin release TM Tagmose, SC Schou, JP Mogensen, FE Nielsen, POG Arkhammar, ... Journal of medicinal chemistry 47 (12), 3202-3211, 2004 | 17 | 2004 |
| Characterization of capsaicin induced responses in mice vas deferens: Evidence of CGRP uptake M Sheykhzade, S Gupta, T Sørensen, OA Sørensen, H Koch, ... European journal of pharmacology 667 (1-3), 375-382, 2011 | 15 | 2011 |
| Effects of a phorbol ester and staurosporine on electro-and pharmacomechanical coupling in a resistance artery HCM Boonen, JGR De Mey European journal of pharmacology 202 (1), 25-32, 1991 | 15 | 1991 |
| In vivo DNA synthesis is not uniformly increased in arterial smooth muscle of young spontaneously hypertensive rats JGR De Mey, MJAP Daemen, HCM Boonen, FT Bosman, EH Dijkstra, ... Journal of hypertension 9 (8), 695-701, 1991 | 15 | 1991 |
| Medicines combinations options and regulatory hurdles OJ Bjerrum, Y Gautam, EJ Bjerrum, M Schmiegelow, HCM Boonen European Journal of Pharmaceutical Sciences 49 (4), 659-663, 2013 | 14 | 2013 |
| Translational value of mechanical and vasomotor properties of mouse isolated mesenteric resistance‐sized arteries EM Outzen, M Zaki, B Abdolalizadeh, A Sams, HCM Boonen, ... Pharmacology Research & Perspectives 3 (6), e00200, 2015 | 11 | 2015 |
| Synthesis and biological activity of 3, 3-Diamino-sulfonylacrylonitriles as novel inhibitors of glucose induced insulin secretion from beta cells TM Tagmose, F Zaragoza, HCM Boonen, A Worsaae, JP Mogensen, ... Bioorganic & medicinal chemistry 11 (6), 931-940, 2003 | 11 | 2003 |
Majid SheykhzadeAssociate professor at the University of Copenhagen, Department of Drug Design and PharmacologyVahvistettu sähköpostiosoite verkkotunnuksessa sund.ku.dk
