Seuraa
Gervais Bérubé
Gervais Bérubé
Associate professor of organic chemistry, Université du Québec à Trois-Rivières
Vahvistettu sähköpostiosoite verkkotunnuksessa uqtr.ca
Nimike
Viittaukset
Viittaukset
Vuosi
An overview of molecular hybrids in drug discovery
G Bérubé
Expert opinion on drug discovery 11 (3), 281-305, 2016
3182016
Intercalation of antitumor drug doxorubicin and its analogue by DNA duplex: structural features and biological implications
D Agudelo, P Bourassa, G Bérubé, HA Tajmir-Riahi
International journal of biological macromolecules 66, 144-150, 2014
2652014
Advances in the development of hybrid anticancer drugs
S Fortin, G Bérubé
Expert opinion on drug discovery 8 (8), 1029-1047, 2013
2572013
Probing the Binding Sites of Antibiotic Drugs Doxorubicin and N-(trifluoroacetyl) Doxorubicin with Human and Bovine Serum Albumins
D Agudelo, P Bourassa, J Bruneau, G Berube, É Asselin, HA Tajmir-Riahi
Public Library of Science 7 (8), e43814, 2012
2242012
Review on the binding of anticancer drug doxorubicin with DNA and tRNA: Structural models and antitumor activity
D Agudelo, P Bourassa, G Bérubé, HA Tajmir-Riahi
Journal of Photochemistry and Photobiology B: Biology 158, 274-279, 2016
1172016
Natural and synthetic biologically active dimeric molecules: anticancer agents, anti-HIV agents, steroid derivatives and opioid antagonists
G Bérubé
Current medicinal chemistry 13 (2), 131-154, 2006
952006
Synthesis of 17β-estradiol platinum (II) complexes: biological evaluation on breast cancer cell lines
C Descôteaux, J Provencher-Mandeville, I Mathieu, V Perron, SK Mandal, ...
Bioorganic & medicinal chemistry letters 13 (22), 3927-3931, 2003
952003
DNA interaction with novel antitumor estradiol–platinum (II) hybrid molecule: a comparative study with cisplatin drug
CN N'soukpoé-Kossi, C Descôteaux, É Asselin, HA Tajmir-Riahi, ...
DNA and cell biology 27 (2), 101-107, 2008
852008
Design, synthesis and biological evaluation of estradiol–chlorambucil hybrids as anticancer agents
A Gupta, P Saha, C Descôteaux, V Leblanc, É Asselin, G Bérubé
Bioorganic & medicinal chemistry letters 20 (5), 1614-1618, 2010
762010
Biological evaluation of novel estrogen-platinum (II) hybrid molecules on uterine and ovarian cancers—molecular modeling studies
V Gagnon, MÈ St-Germain, C Descôteaux, J Provencher-Mandeville, ...
Bioorganic & medicinal chemistry letters 14 (23), 5919-5924, 2004
752004
Synthesis of 17β-estradiol-platinum (II) hybrid molecules showing cytotoxic activity on breast cancer cell lines
J Provencher-Mandeville, C Descôteaux, SK Mandal, V Leblanc, ...
Bioorganic & medicinal chemistry letters 18 (7), 2282-2287, 2008
742008
Improved synthesis of unique estradiol-linked platinum (II) complexes showing potent cytocidal activity and affinity for the estrogen receptor alpha and beta
C Descôteaux, V Leblanc, G Bélanger, S Parent, É Asselin, G Bérubé
Steroids 73 (11), 1077-1089, 2008
712008
Steroid-linked nitrogen mustards as potential anticancer therapeutics: a review
P Saha, C Debnath, G Bérubé
The Journal of steroid biochemistry and molecular biology 137, 271-300, 2013
692013
An overview on the delivery of antitumor drug doxorubicin by carrier proteins
D Agudelo, G Bérubé, HA Tajmir-Riahi
International journal of biological macromolecules 88, 354-360, 2016
662016
Cloning and characterization of norbelladine synthase catalyzing the first committed reaction in Amaryllidaceae alkaloid biosynthesis
A Singh, MA Massicotte, A Garand, L Tousignant, V Ouellette, G Bérubé, ...
BMC plant biology 18, 1-12, 2018
622018
Synthesis, antiproliferative activity and estrogen receptor α affinity of novel estradiol-linked platinum (II) complex analogs to carboplatin and oxaliplatin. Potential vector …
P Saha, C Descôteaux, K Brasseur, S Fortin, V Leblanc, S Parent, ...
European journal of medicinal chemistry 48, 385-390, 2012
612012
Synthesis of 17β-estradiol-linked platinum (II) complexes and their cytocidal activity on estrogen-dependent and-independent breast tumor cells
V Perron, D Rabouin, É Asselin, S Parent, C René, G Bérubé
Bioorganic chemistry 33 (1), 1-15, 2005
612005
tRNA binding to antitumor drug doxorubicin and its analogue
D Agudelo, P Bourassa, M Beauregard, G Bérubé, HA Tajmir-Riahi
PLoS One 8 (7), e69248, 2013
512013
Conjugation of doxorubicin to monoclonal anti-carcinoembryonic antigen antibody via novel thiol-directed cross-linking reagents
A Lau, G Bérubé, CHJ Ford
Bioorganic & Medicinal Chemistry 3 (10), 1299-1304, 1995
471995
Design, synthesis and biological evaluation of estradiol-PEG-linked platinum (II) hybrid molecules: Comparative molecular modeling study of three distinct families of hybrids
J Provencher-Mandeville, C Debnath, SK Mandal, V Leblanc, S Parent, ...
Steroids 76 (1-2), 94-103, 2011
462011
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Artikkelit 1–20