A SARS-CoV-2 protein interaction map reveals targets for drug repurposing DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ... Nature 583 (7816), 459-468, 2020 | 4809 | 2020 |
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 695 | 2020 |
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2 TA Tummino, VV Rezelj, B Fischer, A Fischer, MJ O’meara, B Monel, ... Science 373 (6554), 541-547, 2021 | 191 | 2021 |
Structures of the σ2 receptor enable docking for bioactive ligand discovery A Alon, J Lyu, JM Braz, TA Tummino, V Craik, MJ O’Meara, CM Webb, ... Nature 600 (7890), 759-764, 2021 | 162 | 2021 |
Comparative morphology of gigantopyramidal neurons in primary motor cortex across mammals B Jacobs, ME Garcia, NB Shea‐Shumsky, ME Tennison, M Schall, ... Journal of Comparative Neurology 526 (3), 496-536, 2018 | 54 | 2018 |
Registered replication report on fischer, castel, dodd, and pratt (2003) LJ Colling, D Szűcs, D De Marco, K Cipora, R Ulrich, HC Nuerk, ... Advances in Methods and Practices in Psychological Science 3 (2), 143-162, 2020 | 53 | 2020 |
AlphaFold2 structures guide prospective ligand discovery J Lyu, N Kapolka, R Gumpper, A Alon, L Wang, MK Jain, X Barros-Álvarez, ... Science 384 (6702), eadn6354, 2024 | 47 | 2024 |
Colloidal aggregators in biochemical SARS-CoV-2 repurposing screens HR O’Donnell, TA Tummino, C Bardine, CS Craik, BK Shoichet Journal of medicinal chemistry 64 (23), 17530-17539, 2021 | 35 | 2021 |
Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets KM Haas, MJ McGregor, M Bouhaddou, BJ Polacco, EY Kim, TT Nguyen, ... Nature communications 14 (1), 6030, 2023 | 20 | 2023 |
A multilab registered replication of the attentional SNARC effect. LJ Colling, D Szűcs, D De Marco, K Cipora, R Ulrich, HC Nuerk, ... Advances in Methods and Practices in Psychological Science 3 (2), 143-162, 2020 | 15 | 2020 |
AlphaFold2 structures template ligand discovery J Lyu, N Kapolka, R Gumpper, A Alon, L Wang, MK Jain, X Barros-Álvarez, ... BioRxiv, 2023.12. 20.572662, 2024 | 12 | 2024 |
Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2 TA Tummino, VV Rezelj, B Fischer, A Fischer, MJ O’Meara, B Monel, ... bioRxiv, 2021 | 10 | 2021 |
Crystal structures of the σ2 receptor template large-library docking for selective chemotypes active in vivo A Alon, J Lyu, JM Braz, TA Tummino, V Craik, MJ O’Meara, CM Webb, ... bioRxiv, 2021.04. 29.441652, 2021 | 7 | 2021 |
Simultaneous classification of neuroactive compounds in zebrafish D Myers-Turnbull, JC Taylor, C Helsell, TA Tummino, MN McCarroll, ... bioRxiv, 2020.01. 01.891432, 2020 | 6 | 2020 |
Garc, amp, iacute-Sastre A DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, MJ O'Meara, ... Jura, M. von Zastrow, J. Taunton, O. Schwartz, M. Vignuzzi, C. Enfert, S …, 2020 | 6 | 2020 |
A SARS-CoV-2-human protein-protein interaction map reveals drug targets and potential drug-repurposing [internet] DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, MJ O’Meara Syst Biol, 2020 | 3 | 2020 |
Large library docking for cannabinoid-1 receptor agonists with reduced side effects TA Tummino, C Iliopoulos-Tsoutsouvas, JM Braz, ES O'Brien, RM Stein, ... bioRxiv, 2023.02. 27.530254, 2024 | 2 | 2024 |
Structure-based discovery of cannabinoid-1 receptor agonists with reduced side effects TA Tummino, C Iliopoulos-Tsoutsouvas, JM Braz, ES O’Brien, RM Stein, ... bioRxiv, 2023.02. 27.530254, 2023 | 2 | 2023 |
Applications and Confounds in Drug Discovery and Repurposing TA Tummino University of California, San Francisco, 2023 | | 2023 |
Large-scale docking on the CB1 cannabinoid receptor RM Stein, T Tummino, C Webb, XP Huang, S Slocum, ... Understanding virtual solvent through large. scale ligand discovery 1001 …, 2020 | | 2020 |