Seuraa
Gnana P. Krishnamoorthy
Gnana P. Krishnamoorthy
Vahvistettu sähköpostiosoite verkkotunnuksessa mskcc.org
Nimike
Viittaukset
Viittaukset
Vuosi
Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers
I Landa, T Ibrahimpasic, L Boucai, R Sinha, JA Knauf, RH Shah, S Dogan, ...
The Journal of clinical investigation 126 (3), 1052-1066, 2016
11872016
Sustained ERK inhibition maximizes responses of BrafV600E thyroid cancers to radioiodine
J Nagarajah, M Le, JA Knauf, G Ferrandino, C Montero-Conde, ...
The Journal of clinical investigation 126 (11), 4119-4124, 2016
1362016
Activation of TYRO3/AXL tyrosine kinase receptors in thyroid cancer
E Avilla, V Guarino, C Visciano, F Liotti, M Svelto, GP Krishnamoorthy, ...
Cancer research 71 (5), 1792-1804, 2011
1212011
SWI/SNF complex mutations promote thyroid tumor progression and insensitivity to redifferentiation therapies
M Saqcena, LJ Leandro-Garcia, JLV Maag, V Tchekmedyian, ...
Cancer Discovery 11 (5), 1158-1175, 2021
802021
EIF1AX and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC
GP Krishnamoorthy, NR Davidson, SD Leach, Z Zhao, SW Lowe, G Lee, ...
Cancer discovery 9 (2), 264-281, 2019
792019
Tipifarnib inhibits HRAS-driven dedifferentiated thyroid cancers
BR Untch, V Dos Anjos, MER Garcia-Rendueles, JA Knauf, ...
Cancer research 78 (16), 4642-4657, 2018
772018
Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation
GP Krishnamoorthy, T Guida, L Alfano, E Avilla, M Santoro, F Carlomagno, ...
Journal of Biological Chemistry 288 (24), 17481-17494, 2013
662013
Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia
E Wang, JMB Pineda, WJ Kim, S Chen, J Bourcier, M Stahl, SJ Hogg, ...
Cancer Cell 41 (1), 164-180. e8, 2023
502023
Pathogenesis of cancers derived from thyroid follicular cells
JA Fagin, GP Krishnamoorthy, I Landa
Nature reviews Cancer 23 (9), 631-650, 2023
302023
Genomic and transcriptomic characteristics of metastatic thyroid cancers with exceptional responses to radioactive iodine therapy
L Boucai, M Saqcena, F Kuo, RK Grewal, N Socci, JA Knauf, ...
Clinical Cancer Research 29 (8), 1620-1630, 2023
252023
Yap governs a lineage-specific neuregulin1 pathway-driven adaptive resistance to RAF kinase inhibitors
MER Garcia-Rendueles, G Krishnamoorthy, M Saqcena, A Acuña-Ruiz, ...
Molecular Cancer 21 (1), 213, 2022
232022
Selpercatinib-induced hypothyroidism through off-target inhibition of type 2 iodothyronine deiodinase
L Boucai, F Salas-Lucia, GP Krishnamoorthy, E Sherman, CM Rudin, ...
JCO Precision Oncology 6, e2100496, 2022
152022
Co-inhibition of SMAD and MAPK signaling enhances 124I uptake in BRAF-mutant thyroid cancers
KA Luckett, JR Cracchiolo, GP Krishnamoorthy, LJ Leandro-Garcia, ...
Endocrine-Related Cancer 28 (6), 391-402, 2021
152021
Telomerase Upregulation Induces Progression of Mouse BrafV600E-Driven Thyroid Cancers and Triggers Nontelomeric Effects
I Landa, CEM Thornton, B Xu, J Haase, GP Krishnamoorthy, J Hao, ...
Molecular Cancer Research 21 (11), 1163-1175, 2023
82023
RBM10 loss in thyroid cancer leads to aberrant splicing of cytoskeletal and extracellular matrix mRNAs and increased metastatic fitness
GP Krishnamoorthy, A Glover, B Untch, M Saqcena, D Vukel, K Berman, ...
Cancer Research 82 (12_Supplement), 986-986, 2022
32022
Targetable treatment resistance in thyroid cancer with clonal hematopoiesis
V Tiedje, PS Vela, JL Yang, BR Untch, L Boucai, AJ Stonestrom, AB Costa, ...
bioRxiv, 2024.10. 10.617685, 2024
12024
RBM10 loss induces aberrant splicing of cytoskeletal and extracellular matrix mRNAs and promotes metastatic fitness
GP Krishnamoorthy, AR Glover, BR Untch, N Sigcha-Coello, B Xu, ...
bioRxiv, 2024
12024
Telomerase reactivation induces progression of mouse BrafV600E-driven thyroid cancers without telomere lengthening
I Landa, CEM Thornton, B Xu, J Haase, GP Krishnamoorthy, J Hao, ...
bioRxiv, 2023
12023
Functional characterization of EIF1AX mutations in thyroid cancer predicts for gain of function by increasing translational rate with concomitant derepression of upstream …
GP Krishnamoorthy, I Landa, JA Knauf, J Nagarajah, G Rätsch, ...
Cancer Research 76 (14_Supplement), 892-892, 2016
12016
RBM10 loss promotes metastases by aberrant splicing of cytoskeletal and extracellular matrix mRNAs
GP Krishnamoorthy, AR Glover, BR Untch, N Sigcha-Coello, B Xu, ...
Journal of Experimental Medicine 222 (5), 2025
2025
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Artikkelit 1–20