| Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors Z Jin, X Du, Y Xu, Y Deng, M Liu, Y Zhao, B Zhang, X Li, L Zhang, C Peng, ... Nature 582 (7811), 289-293, 2020 | 4355 | 2020 |
| Design of wide-spectrum inhibitors targeting coronavirus main proteases H Yang, W Xie, X Xue, K Yang, J Ma, W Liang, Q Zhao, Z Zhou, D Pei, ... PLoS biology 3 (10), e324, 2005 | 795 | 2005 |
| Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur Z Jin, Y Zhao, Y Sun, B Zhang, H Wang, Y Wu, Y Zhu, C Zhu, T Hu, X Du, ... Nature structural & molecular biology 27 (6), 529-532, 2020 | 433 | 2020 |
| A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway MA Cohn, P Kowal, K Yang, W Haas, TT Huang, SP Gygi, AD D'Andrea Molecular cell 28 (5), 786-797, 2007 | 399 | 2007 |
| Mitochondrial control by DRP1 in brain tumor initiating cells Q Xie, Q Wu, CM Horbinski, WA Flavahan, K Yang, W Zhou, ... Nature neuroscience 18 (4), 501-510, 2015 | 396 | 2015 |
| Production of authentic SARS-CoV Mpro with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction X Xue, H Yang, W Shen, Q Zhao, J Li, K Yang, C Chen, Y Jin, M Bartlam, ... Journal of molecular biology 366 (3), 965-975, 2007 | 272 | 2007 |
| Reciprocal signaling between glioblastoma stem cells and differentiated tumor cells promotes malignant progression X Wang, BC Prager, Q Wu, LJY Kim, RC Gimple, Y Shi, K Yang, ... Cell stem cell 22 (4), 514-528. e5, 2018 | 253 | 2018 |
| Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332 Y Zhao, C Fang, Q Zhang, R Zhang, X Zhao, Y Duan, H Wang, Y Zhu, ... Protein & cell 13 (9), 689-693, 2022 | 202 | 2022 |
| Purine synthesis promotes maintenance of brain tumor initiating cells in glioma X Wang, K Yang, Q Xie, Q Wu, SC Mack, Y Shi, LJY Kim, BC Prager, ... Nature neuroscience 20 (5), 661-673, 2017 | 199 | 2017 |
| Structure of main protease from human coronavirus NL63: insights for wide spectrum anti-coronavirus drug design F Wang, C Chen, W Tan, K Yang, H Yang Scientific reports 6 (1), 22677, 2016 | 194 | 2016 |
| Regulation of Rev1 by the Fanconi anemia core complex H Kim, K Yang, D Dejsuphong, AD D'Andrea Nature structural & molecular biology 19 (2), 164-170, 2012 | 169 | 2012 |
| The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response M Huang, JM Kim, B Shiotani, K Yang, L Zou, AD D'Andrea Molecular cell 39 (2), 259-268, 2010 | 169 | 2010 |
| Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1 K Lee, K Yang, MA Cohn, N Sikdar, AD D'Andrea, K Myung Journal of Biological Chemistry 285 (14), 10362-10369, 2010 | 154 | 2010 |
| The USP1/UAF1 complex promotes double-strand break repair through homologous recombination J Murai, K Yang, D Dejsuphong, K Hirota, S Takeda, AD D'Andrea Molecular and cellular biology 31 (12), 2462-2469, 2011 | 150 | 2011 |
| Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells X Wang, K Yang, Q Wu, LJY Kim, AR Morton, RC Gimple, BC Prager, ... Science translational medicine 11 (504), eaau4972, 2019 | 147 | 2019 |
| Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination X Fang, W Zhou, Q Wu, Z Huang, Y Shi, K Yang, C Chen, Q Xie, SC Mack, ... Journal of Experimental Medicine 214 (1), 245-267, 2017 | 147 | 2017 |
| High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors Y Zhao, X Du, Y Duan, X Pan, Y Sun, T You, L Han, Z Jin, W Shang, J Yu, ... Protein & cell 12 (11), 877-888, 2021 | 136 | 2021 |
| Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2 Y Zhao, Y Zhu, X Liu, Z Jin, Y Duan, Q Zhang, C Wu, L Feng, X Du, J Zhao, ... Proceedings of the National Academy of Sciences 119 (16), e2117142119, 2022 | 132 | 2022 |
| MYC-regulated mevalonate metabolism maintains brain tumor–initiating cells X Wang, Z Huang, Q Wu, BC Prager, SC Mack, K Yang, LJY Kim, ... Cancer research 77 (18), 4947-4960, 2017 | 120 | 2017 |
| Regulation of the Fanconi anemia pathway by a SUMO-like delivery network K Yang, GL Moldovan, P Vinciguerra, J Murai, S Takeda, AD D'Andrea Genes & development 25 (17), 1847-1858, 2011 | 114 | 2011 |
