Pharmacological inhibition of NLRP3 inflammasome attenuates myocardial ischemia/reperfusion injury by activation of RISK and mitochondrial pathways R Mastrocola, C Penna, F Tullio, S Femminò, D Nigro, F Chiazza, L Serpe, ... Oxidative Medicine and Cellular Longevity 2016 (1), 5271251, 2016 | 141 | 2016 |
Fructose liquid and solid formulations differently affect gut integrity, microbiota composition and related liver toxicity: a comparative in vivo study R Mastrocola, I Ferrocino, E Liberto, F Chiazza, AS Cento, D Collotta, ... The Journal of Nutritional Biochemistry 55, 185-199, 2018 | 80 | 2018 |
Inhibition of Bruton's TK regulates macrophage NF‐κB and NLRP3 inflammasome activation in metabolic inflammation GSD Purvis, M Collino, H Aranda‐Tavio, F Chiazza, CE O'Riordan, ... British journal of pharmacology 177 (19), 4416-4432, 2020 | 74 | 2020 |
Identification of AnnexinA1 as an endogenous regulator of RhoA, and its role in the pathophysiology and experimental therapy of type-2 diabetes GSD Purvis, M Collino, RA Loiola, A Baragetti, F Chiazza, M Brovelli, ... Frontiers in Immunology 10, 571, 2019 | 64 | 2019 |
Effects of exogenous dietary advanced glycation end products on the cross-talk mechanisms linking microbiota to metabolic inflammation R Mastrocola, D Collotta, G Gaudioso, M Le Berre, AS Cento, ... Nutrients 12 (9), 2497, 2020 | 61 | 2020 |
Antisense oligonucleotides: A novel Frontier in pharmacological strategy D Collotta, I Bertocchi, E Chiapello, M Collino Frontiers in Pharmacology 14, 1304342, 2023 | 60 | 2023 |
Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis E Zechendorf, CE O’Riordan, L Stiehler, N Wischmeyer, F Chiazza, ... JCI insight 5 (8), e131571, 2020 | 48 | 2020 |
Bruton's tyrosine kinase inhibition attenuates the cardiac dysfunction caused by cecal ligation and puncture in mice CE O'Riordan, GSD Purvis, D Collotta, F Chiazza, B Wissuwa, S Al Zoubi, ... Frontiers in Immunology 10, 2129, 2019 | 45 | 2019 |
The hidden role of NLRP3 inflammasome in obesity‐related COVID‐19 exacerbations: lessons for drug repurposing I Bertocchi, F Foglietta, D Collotta, C Eva, V Brancaleone, C Thiemermann, ... British journal of pharmacology 177 (21), 4921-4930, 2020 | 41 | 2020 |
Linagliptin attenuates the cardiac dysfunction associated with experimental sepsis in mice with pre-existing type 2 diabetes by inhibiting NF-κB S Al Zoubi, J Chen, C Murphy, L Martin, F Chiazza, D Collotta, ... Frontiers in immunology 9, 2996, 2018 | 38 | 2018 |
X-linked immunodeficient mice with no functional Bruton's tyrosine kinase are protected from sepsis-induced multiple organ failure CE O'Riordan, GSD Purvis, D Collotta, N Krieg, B Wissuwa, MH Sheikh, ... Frontiers in immunology 11, 581758, 2020 | 32 | 2020 |
RvE1 attenuates polymicrobial sepsis-induced cardiac dysfunction and enhances bacterial clearance J Chen, GSD Purvis, D Collotta, S Al Zoubi, MA Sugimoto, A Cacace, ... Frontiers in immunology 11, 2080, 2020 | 31 | 2020 |
Baricitinib counteracts metaflammation, thus protecting against diet-induced metabolic abnormalities in mice D Collotta, W Hull, R Mastrocola, F Chiazza, AS Cento, C Murphy, R Verta, ... Molecular Metabolism 39, 101009, 2020 | 28 | 2020 |
Ticagrelor conditioning effects are not additive to cardioprotection induced by direct NLRP3 inflammasome inhibition: role of RISK, NLRP3, and redox cascades C Penna, M Aragno, AS Cento, S Femminò, I Russo, FD Bello, F Chiazza, ... Oxidative medicine and cellular longevity 2020 (1), 9219825, 2020 | 28 | 2020 |
Protective Effects of Pyridoxamine Supplementation in the Early Stages of Diet‐Induced Kidney Dysfunction F Chiazza, AS Cento, D Collotta, D Nigro, G Rosa, F Baratta, V Bitonto, ... BioMed research international 2017 (1), 2682861, 2017 | 26 | 2017 |
Resolvin D1 attenuates the organ injury associated with experimental hemorrhagic shock R Sordi, F Chiazza, D Collotta, G Migliaretti, RA Colas, P Vulliamy, ... Annals of surgery 273 (5), 1012-1021, 2021 | 25 | 2021 |
Pharmacological inhibition of FAK-Pyk2 pathway protects against organ damage and prolongs the survival of septic mice GF Alves, E Aimaretti, G Einaudi, R Mastrocola, JG de Oliveira, D Collotta, ... Frontiers in Immunology 13, 837180, 2022 | 19 | 2022 |
In Vitro Evaluation of the Toxicological Profile and Oxidative Stress of Relevant Diet‐Related Advanced Glycation End Products and Related 1, 2‐Dicarbonyls V Cepas, F Manig, JC Mayo, M Hellwig, D Collotta, V Sanmartino, ... Oxidative medicine and cellular longevity 2021 (1), 9912240, 2021 | 19 | 2021 |
Altered hepatic sphingolipid metabolism in insulin resistant mice: Role of advanced glycation endproducts R Mastrocola, F Dal Bello, AS Cento, K Gaens, D Collotta, M Aragno, ... Free Radical Biology and Medicine 169, 425-435, 2021 | 16 | 2021 |
Recent advances in JAK inhibitors for the treatment of metabolic syndrome D Collotta, MP Franchina, V Carlucci, M Collino Frontiers in Pharmacology 14, 1245535, 2023 | 15 | 2023 |