| Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics Y Gupta, OV Savytskyi, M Coban, A Venugopal, V Pleqi, CA Weber, ... Molecular Aspects of Medicine 91, 101151, 2023 | 35 | 2023 |
| PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma H Ma, A Hockla, C Mehner, M Coban, N Papo, DC Radisky, ES Radisky Scientific reports 9 (1), 1844, 2019 | 33 | 2019 |
| Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin I Cohen, M Coban, A Shahar, B Sankaran, A Hockla, S Lacham, ... Journal of Biological Chemistry 294 (13), 5105-5120, 2019 | 26 | 2019 |
| Attacking COVID-19 progression using multi-drug therapy for synergetic target engagement MA Coban, J Morrison, S Maharjan, DH Hernandez Medina, W Li, ... Biomolecules 11 (6), 787, 2021 | 24 | 2021 |
| Targeting an autocrine IL-6–SPINK1 signaling axis to suppress metastatic spread in ovarian clear cell carcinoma C Mehner, E Miller, A Hockla, M Coban, SJ Weroha, DC Radisky, ... Oncogene 39 (42), 6606-6618, 2020 | 22 | 2020 |
| Substitution of PINK1 Gly411 modulates substrate receptivity and turnover FC Fiesel, D Fričová, CS Hayes, MA Coban, R Hudec, JM Bredenberg, ... Autophagy 19 (6), 1711-1732, 2023 | 19 | 2023 |
| Engineering of tissue inhibitor of metalloproteinases TIMP-1 for fine discrimination between closely related stromelysins MMP-3 and MMP-10 M Raeeszadeh-Sarmazdeh, M Coban, S Mahajan, A Hockla, B Sankaran, ... Journal of Biological Chemistry 298 (3), 2022 | 19 | 2022 |
| Unveiling an indole alkaloid diketopiperazine biosynthetic pathway that features a unique stereoisomerase and multifunctional methyltransferase G Deletti, SD Green, C Weber, KN Patterson, SS Joshi, TM Khopade, ... Nature communications 14 (1), 2558, 2023 | 17 | 2023 |
| Molecular Dynamics Simulations Suggest a Non-Doublet Decoding Model of −1 Frameshifting by tRNASer3 T Caulfield, M Coban, A Tek, SC Flores Biomolecules 9 (11), 745, 2019 | 10 | 2019 |
| Activity-based protein profiling reveals active serine proteases that drive malignancy of human ovarian clear cell carcinoma C Mehner, A Hockla, M Coban, B Madden, R Estrada, DC Radisky, ... Journal of Biological Chemistry 298 (8), 102146, 2022 | 8 | 2022 |
| Structure and computation-guided yeast surface display for the evolution of TIMP-based matrix metalloproteinase inhibitors A Shoari, G Khalili-Tanha, MA Coban, ES Radisky Frontiers in Molecular Biosciences 10, 1321956, 2023 | 6 | 2023 |
| Structural models for the dynamic effects of loss-of-function variants in the human SIM1 protein transcriptional activation domain MA Coban, PR Blackburn, ML Whitelaw, MM Haelst, PS Atwal, ... Biomolecules 10 (9), 1314, 2020 | 6 | 2020 |
| Enyzmes| Matrix metalloproteinases ES Radisky, M Coban Encyclopedia of Biological Chemistry: Third Edition, 336-353, 2021 | 5 | 2021 |
| In Silico Investigation of Parkin-Activating Mutations Using Simulations and Network Modeling NN Islam, CA Weber, M Coban, LT Cocker, FC Fiesel, W Springer, ... Biomolecules 14 (3), 365, 2024 | 4 | 2024 |
| Structural and computational perspectives of selectively targeting mutant proteins MA Coban, S Fraga, TR Caulfield Current Drug Discovery Technologies 18 (3), 365-378, 2021 | 4 | 2021 |
| Targeting Tmprss2, S-protein: ace2, and 3CLpro for synergetic inhibitory engagement M Coban, J Morrison, W Freeman, ES Radisky, K Le Roch, T Caulfield | 4 | 2020 |
| A virtual screening platform identifies chloroethylagelastatin a as a potential ribosomal inhibitor TR Caulfield, KE Hayes, Y Qiu, M Coban, J Seok Oh, AL Lane, ... Biomolecules 10 (10), 1407, 2020 | 3 | 2020 |
| Engineering protein therapeutics for cancer based on the natural matrix metalloproteinase inhibitor TIMP‐1 M Raeeszadeh-Sarmazdeh, M Coban, B Sankaran, E Radisky The FASEB Journal 34 (S1), 1-1, 2020 | 3 | 2020 |
| Utilizing genetic code expansion to modify N-TIMP2 specificity towards MMP-2, MMP-9, and MMP-14 H Hayun, M Coban, AK Bhagat, E Ozer, L Alfonta, TR Caulfield, ... Scientific reports 13 (1), 5186, 2023 | 2 | 2023 |
| Improving Circulation Half-Life of Therapeutic Candidate N-TIMP2 by Unfolded Peptide Extension J Shirian, A Hockla, JJ Gleba, M Coban, N Rotenberg, LM Strik, ... Biomolecules 14 (9), 1187, 2024 | 1 | 2024 |