| Site-specific C-terminal and internal loop labeling of proteins using sortase-mediated reactions CP Guimaraes, MD Witte, CS Theile, G Bozkurt, L Kundrat, AEM Blom, ... Nature protocols 8 (9), 1787-1799, 2013 | 406 | 2013 |
| Site-specific N-terminal labeling of proteins using sortase-mediated reactions CS Theile, MD Witte, AEM Blom, L Kundrat, HL Ploegh, CP Guimaraes Nature protocols 8 (9), 1800-1807, 2013 | 318 | 2013 |
| Ultrasensitive in situ visualization of active glucocerebrosidase molecules MD Witte, WW Kallemeijn, J Aten, KY Li, A Strijland, WE Donker-Koopman, ... Nature chemical biology 6 (12), 907-913, 2010 | 300 | 2010 |
| A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo M Verdoes, BI Florea, V Menendez-Benito, CJ Maynard, MD Witte, ... Chemistry & biology 13 (11), 1217-1226, 2006 | 250 | 2006 |
| Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo WW Kallemeijn, KY Li, MD Witte, ARA Marques, J Aten, S Scheij, J Jiang, ... Angewandte Chemie International Edition 51 (50), 12529-12533, 2012 | 167 | 2012 |
| Biomarkers in the diagnosis of lysosomal storage disorders: proteins, lipids, and inhibodies JMFG Aerts, WW Kallemeijn, W Wegdam, M Joao Ferraz, ... Journal of inherited metabolic disease 34, 605-619, 2011 | 167 | 2011 |
| Preparation of unnatural N-to-N and C-to-C protein fusions MD Witte, JJ Cragnolini, SK Dougan, NC Yoder, MW Popp, HL Ploegh Proceedings of the National Academy of Sciences 109 (30), 11993-11998, 2012 | 158 | 2012 |
| Identification of early intermediates of caspase activation using selective inhibitors and activity-based probes AB Berger, MD Witte, JB Denault, AM Sadaghiani, KMB Sexton, ... Molecular cell 23 (4), 509-521, 2006 | 145 | 2006 |
| Bruton's Tyrosine Kinase (BTK) and Vav1 Contribute to Dectin1-Dependent Phagocytosis of Candida albicans in Macrophages K Strijbis, FG Tafesse, GD Fairn, MD Witte, SK Dougan, N Watson, ... PLoS pathogens 9 (6), e1003446, 2013 | 103 | 2013 |
| Bispecific antibody generated with sortase and click chemistry has broad antiinfluenza virus activity K Wagner, MJ Kwakkenbos, YB Claassen, K Maijoor, M Böhne, ... Proceedings of the National Academy of Sciences 111 (47), 16820-16825, 2014 | 99 | 2014 |
| Production of unnaturally linked chimeric proteins using a combination of sortase-catalyzed transpeptidation and click chemistry MD Witte, CS Theile, T Wu, CP Guimaraes, AEM Blom, HL Ploegh Nature protocols 8 (9), 1808-1819, 2013 | 82 | 2013 |
| Site-selective carbon–carbon bond formation in unprotected monosaccharides using photoredox catalysis ICS Wan, MD Witte, AJ Minnaard Chemical Communications 53 (36), 4926-4929, 2017 | 80 | 2017 |
| Site-specific protein modification using immobilized sortase in batch and continuous-flow systems MD Witte, T Wu, CP Guimaraes, CS Theile, AEM Blom, JR Ingram, Z Li, ... Nature protocols 10 (3), 508-516, 2015 | 80 | 2015 |
| From covalent glycosidase inhibitors to activity‐based glycosidase probes LI Willems, J Jiang, KY Li, MD Witte, WW Kallemeijn, TJN Beenakker, ... Chemistry–A European Journal 20 (35), 10864-10872, 2014 | 70 | 2014 |
| Monovalent engagement of the BCR activates ovalbumin-specific transnuclear B cells AM Avalos, AM Bilate, MD Witte, AK Tai, J He, MP Frushicheva, PD Thill, ... Journal of Experimental Medicine 211 (2), 365-379, 2014 | 65 | 2014 |
| A cleavable linker based on the levulinoyl ester for activity-based protein profiling PP Geurink, BI Florea, N Li, MD Witte, J Verasdonck, CL Kuo, ... Angewandte Chemie International Edition 49 (38), 6802-6805, 2010 | 65 | 2010 |
| Design of cell-permeable, fluorescent activity-based probes for the lysosomal cysteine protease asparaginyl endopeptidase (AEP)/legumain KB Sexton, MD Witte, G Blum, M Bogyo Bioorganic & medicinal chemistry letters 17 (3), 649-653, 2007 | 64 | 2007 |
| From d- to l-Monosaccharide Derivatives via Photodecarboxylation–Alkylation ICS Wan, MD Witte, AJ Minnaard Organic letters 21 (18), 7669-7673, 2019 | 61 | 2019 |
| NIS/TFA: a general method for hydrolyzing thioglycosides J Dinkelaar, MD Witte, LJ van den Bos, HS Overkleeft, GA van der Marel Carbohydrate research 341 (10), 1723-1729, 2006 | 56 | 2006 |
| Novel aza peptide inhibitors and active‐site probes of papain‐family cysteine proteases SHL Verhelst, MD Witte, S Arastu‐Kapur, M Fonovic, M Bogyo ChemBioChem 7 (6), 943-950, 2006 | 56 | 2006 |
