| Fullerene derivatives as dual inhibitors of HIV-1 reverse transcriptase and protease T Yasuno, T Ohe, H Kataoka, K Hashimoto, Y Ishikawa, K Furukawa, ... Bioorganic & Medicinal Chemistry Letters 31, 127675, 2021 | 29 | 2021 |
| Stepwise binding of inhibitors to human cytochrome P450 17A1 and rapid kinetics of inhibition of androgen biosynthesis FP Guengerich, KD McCarty, JG Chapman, Y Tateishi Journal of Biological Chemistry 297 (2), 2021 | 13 | 2021 |
| Processive kinetics in the three-step lanosterol 14α-demethylation reaction catalyzed by human cytochrome P450 51A1 KD McCarty, ME Sullivan, Y Tateishi, TY Hargrove, GI Lepesheva, ... Journal of Biological Chemistry 299 (7), 2023 | 12 | 2023 |
| Development of novel diclofenac analogs designed to avoid metabolic activation and hepatocyte toxicity Y Tateishi, T Ohe, M Ogawa, K Takahashi, S Nakamura, T Mashino ACS omega 5 (50), 32608-32616, 2020 | 11 | 2020 |
| Oxygen‐18 Labeling Reveals a Mixed Fe− O Mechanism in the Last Step of Cytochrome P450 51 Sterol 14α‐Demethylation KD McCarty, Y Tateishi, TY Hargrove, GI Lepesheva, FP Guengerich Angewandte Chemie International Edition 63 (9), e202317711, 2024 | 9 | 2024 |
| Synthesis and evaluation of nevirapine analogs to study the metabolic activation of nevirapine Y Tateishi, T Ohe, D Yasuda, K Takahashi, S Nakamura, Y Kazuki, ... Drug Metabolism and Pharmacokinetics 35 (2), 238-243, 2020 | 8 | 2020 |
| The multistep oxidation of cholesterol to pregnenolone by human cytochrome P450 11A1 is highly processive KD McCarty, L Liu, Y Tateishi, HL Wapshott-Stehli, FP Guengerich Journal of Biological Chemistry 300 (1), 105495, 2024 | 7 | 2024 |
| 3, 4-Desaturation of retinoic acid by cytochrome P450 27C1 prevents P450-mediated catabolism SM Glass, Y Tateishi, FP Guengerich, HJ Wang Archives of biochemistry and biophysics 743, 109669, 2023 | 7 | 2023 |
| Oxygen-18 labeling defines a ferric peroxide (Compound 0) mechanism in the oxidative deformylation of aldehydes by cytochrome P450 2B4 Y Tateishi, KD McCarty, MV Martin, FP Guengerich ACS catalysis 14 (4), 2388-2394, 2024 | 5 | 2024 |
| Steroid 17α-hydroxylase/17, 20-lyase (cytochrome P450 17A1) FP Guengerich, KD McCarty, Y Tateishi, L Liu Methods in enzymology 689, 39-63, 2023 | 5 | 2023 |
| Cytochrome b5 binds tightly to several human cytochrome P450 enzymes D Kim, V Kim, Y Tateishi, FP Guengerich Drug Metabolism and Disposition 49 (10), 902-909, 2021 | 5 | 2021 |
| Roles of Ferric Peroxide Anion Intermediates (Fe3+O2−, Compound 0) in Cytochrome P450 19A1 Steroid Aromatization and a Cytochrome P450 2B4 Secosteroid … Y Tateishi, KD McCarty, MV Martin, FK Yoshimoto, FP Guengerich Angewandte Chemie 136 (33), e202406542, 2024 | 4 | 2024 |
| Synthesis and evaluation of tofacitinib analogs designed to mitigate metabolic activation Y Tateishi, C Shibazaki, K Takahashi, S Nakamura, Y Kazuki, T Mashino, ... Drug Metabolism and Pharmacokinetics 43, 100439, 2022 | 4 | 2022 |
| Proteomics, modeling, and fluorescence assays delineate cytochrome b5 residues involved in binding and stimulation of cytochrome P450 17A1 17, 20-lyase Y Tateishi, SN Webb, B Li, L Liu, KL Rose, M Leser, P Patel, ... Journal of Biological Chemistry 300 (3), 2024 | 3 | 2024 |
| CC bond cleavage reactions catalyzed by cytochrome P450 enzymes FP Guengerich, Y Tateishi, KD McCarty Medicinal Chemistry Research 32 (7), 1263-1277, 2023 | 3 | 2023 |
| Updates on mechanisms of cytochrome P450 catalysis of complex steroid oxidations FP Guengerich, Y Tateishi, KD McCarty, FK Yoshimoto International Journal of Molecular Sciences 25 (16), 9020, 2024 | 2 | 2024 |
Fred GuengerichProfessor of Biochemistry, Vanderbilt UniversityVahvistettu sähköpostiosoite verkkotunnuksessa vanderbilt.edu
