Seuraa
Krina Mehta
Krina Mehta
Leiden University, Kyowa Kirin
Vahvistettu sähköpostiosoite verkkotunnuksessa kyowakirin.com
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Viittaukset
Viittaukset
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Optimizing ethambutol dosing among HIV/tuberculosis co-infected patients: A population pharmacokinetic modelling and simulation study
K Mehta, S Ravimohan, JG Pasipanodya, S Srivastava, C Modongo, ...
Journal of Antimicrobial Chemotherapy 74 (10), 2994-3002, 2019
132019
Predictions of bedaquiline and pretomanid target attainment in lung lesions of tuberculosis patients using translational minimal physiologically based pharmacokinetic modeling
K Mehta, T Guo, PH Van Der Graaf, JGC van Hasselt
Clinical Pharmacokinetics 62 (3), 519-532, 2023
122023
Host-directed therapies for tuberculosis: quantitative systems pharmacology approaches
K Mehta, HP Spaink, THM Ottenhoff, PH van der Graaf, JGC van Hasselt
Trends in Pharmacological Sciences 43 (4), 293-304, 2022
122022
Predictions of bedaquiline central nervous system exposure in patients with tuberculosis meningitis using physiologically based pharmacokinetic modeling
K Mehta, P Balazki, PH van der Graaf, T Guo, JGC van Hasselt
Clinical Pharmacokinetics 63 (5), 657-668, 2024
32024
Model‐based dose optimization framework for bedaquiline, pretomanid and linezolid for the treatment of drug‐resistant tuberculosis
K Mehta, T Guo, PH Van der Graaf, JGC van Hasselt
British Journal of Clinical Pharmacology 90 (2), 463-474, 2024
32024
Pharmacogenetic variability and the probability of site of action target attainment during tuberculosis meningitis treatment: A physiologically based pharmacokinetic modeling …
K Mehta, N Narayanan, SK Heysell, GP Bisson, S Subbian, N Kurepina, ...
Tuberculosis 137, 102271, 2022
32022
Leveraging innovative technology to generate drug response phenotypes for the advancement of biomarker‐driven precision dosing
A Oni‐Orisan, N Srinivas, K Mehta, JL Das, TT Nguyen, GH Tison, ...
Clinical and translational science 14 (3), 784-790, 2021
32021
Quantitative systems pharmacology modeling framework of autophagy in tuberculosis: application to adjunctive metformin host-directed therapy
K Mehta, T Guo, RS Wallis, PH van der Graaf, JGC van Hasselt
Antimicrobial Agents and Chemotherapy 66 (8), e00366-22, 2022
22022
Pharmacodynamic Exposure–Response Analysis of Fracture Count Data Following Treatment with Burosumab in Patients with XLH
K Mehta, J Storopoli, N Ramwani, E Quattrocchi, J Gobburu, T Weber, ...
The Journal of Clinical Pharmacology 65 (2), 253-260, 2025
2025
Model‐Informed Approach to Recommend Burosumab Dosing Regimens for Pediatric and Adult Patients With the Ultrarare Disease Tumor‐Induced Osteomalacia
MW Hruska, L Sid‐Otmane, NH Gosselin, E Quattrocchi, SK Lee, ...
Clinical Pharmacology & Therapeutics 116 (6), 1606-1614, 2024
2024
Item Response Theory Quantifies the Relationship Between Improvements in Serum Phosphate and Patient‐Reported Outcomes in Adults With X‐Linked Hypophosphatemia
K Mehta, NH Gosselin, K Insogna, O Barriere, E Quattrocchi, MW Hruska, ...
Clinical Pharmacology & Therapeutics 116 (5), 1343-1351, 2024
2024
Model-Informed Drug Approach to Recommend Therapeutic Burosumab Dosing Regimens for Pediatric and Adult Patients with Tumor-Induced Osteomalacia
M Hruska, L Sid-Otmane, N Gosselin, E Quattrocchi, SK Lee, MA Mascelli, ...
2024
Quantitative Systems Pharmacology approaches for Development of Host-Directed Therapies against Mycobacterium tuberculosis infections
K Mehta, H Spaink, T Ottenhoff, P van der Graaf, JGC van Hasselt
ESS Open Archive eprints 212, 21226061, 2024
2024
an der, & Hasselt
KM Mehta, T Guo, PH Graaf
GC an, 519-532, 2023
2023
Rationale for the Clinical Use of Less Frequent Dosing of Mogamulizumab for T-Cell Lymphomas Using Population Pharmacokinetic and Exposure Response Analysis
K Mehta, D Patel, R Vuppugalla, A Tudor, K Dwyer, M Hruska, ...
Blood 138, 2475, 2021
2021
Population pharmacokinetic-pharmacodynamic analysis of KHK2455 in patients with locally advanced or metastatic solid tumors
K Mehta, S Koshiba, M Hasegawa, T Tayama, D Marsteller, F Fox, Y Liu, ...
Cancer Research 81 (13_Supplement), 1368-1368, 2021
2021
Leveraging innovative technology to generate drug response phenotypes for the
A Oni-Orisan, N Srinivas, K Mehta
Clinical and translational science, 14 (3), 2021
2021
Consider ASCPT in Your End-of-Year Giving
D Wyatt, D Strauss, B Ray, K Mehta, T Vaidya, U Simonsson
Clinical Pharmacology and Therapeutics 105 (1), 17-21, 2019
2019
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Artikkelit 1–18