| A programmable dual-RNA–guided DNA endonuclease in adaptive bacterial immunity M Jinek, K Chylinski, I Fonfara, M Hauer, JA Doudna, E Charpentier science 337 (6096), 816-821, 2012 | 20662 | 2012 |
| RNA-programmed genome editing in human cells M Jinek, A East, A Cheng, S Lin, E Ma, J Doudna elife 2, e00471, 2013 | 2979 | 2013 |
| DNA interrogation by the CRISPR RNA-guided endonuclease Cas9 SH Sternberg, S Redding, M Jinek, EC Greene, JA Doudna Biophysical Journal 106 (2), 695a, 2014 | 2459 | 2014 |
| Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease C Anders, O Niewoehner, A Duerst, M Jinek Nature 513 (7519), 569-573, 2014 | 1747 | 2014 |
| Structures of Cas9 endonucleases reveal RNA-mediated conformational activation M Jinek, F Jiang, DW Taylor, SH Sternberg, E Kaya, E Ma, C Anders, ... Science 343 (6176), 1247997, 2014 | 1647 | 2014 |
| Sequence-and structure-specific RNA processing by a CRISPR endonuclease RE Haurwitz, M Jinek, B Wiedenheft, K Zhou, JA Doudna Science 329 (5997), 1355-1358, 2010 | 1063 | 2010 |
| A three-dimensional view of the molecular machinery of RNA interference M Jinek, JA Doudna nature 457 (7228), 405-412, 2009 | 1031 | 2009 |
| Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription JA Doudna, M Jinek, E Charpentier, K Chylinski US Patent 10,266,850, 2019 | 960 | 2019 |
| A prudent path forward for genomic engineering and germline gene modification D Baltimore, P Berg, M Botchan, D Carroll, RA Charo, G Church, JE Corn, ... Science 348 (6230), 36-38, 2015 | 938 | 2015 |
| Structural biology of nucleocytoplasmic transport A Cook, F Bono, M Jinek, E Conti Annu. Rev. Biochem. 76 (1), 647-671, 2007 | 639 | 2007 |
| Structural basis for guide RNA processing and seed-dependent DNA targeting by CRISPR-Cas12a DC Swarts, J van der Oost, M Jinek Molecular cell 66 (2), 221-233. e4, 2017 | 573 | 2017 |
| Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation MR Fabian, G Mathonnet, T Sundermeier, H Mathys, JT Zipprich, ... Molecular cell 35 (6), 868-880, 2009 | 544 | 2009 |
| Structural insights into the molecular mechanism of the m6A writer complex P Śledź, M Jinek elife 5, e18434, 2016 | 526 | 2016 |
| Type III CRISPR–Cas systems produce cyclic oligoadenylate second messengers O Niewoehner, C Garcia-Doval, JT Rostøl, C Berk, F Schwede, L Bigler, ... Nature 548 (7669), 543-548, 2017 | 458 | 2017 |
| Mechanistic insights into the cis-and trans-acting DNase activities of Cas12a DC Swarts, M Jinek Molecular cell 73 (3), 589-600. e4, 2019 | 447 | 2019 |
| The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin α M Jínek, J Rehwinkel, BD Lazarus, E Izaurralde, JA Hanover, E Conti Nature structural & molecular biology 11 (10), 1001-1007, 2004 | 380 | 2004 |
| An RNA-induced conformational change required for CRISPR RNA cleavage by the endoribonuclease Cse3 DG Sashital, M Jinek, JA Doudna Nature structural & molecular biology 18 (6), 680-687, 2011 | 342 | 2011 |
| Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated genome defense B Wiedenheft, K Zhou, M Jinek, SM Coyle, W Ma, JA Doudna Structure 17 (6), 904-912, 2009 | 341 | 2009 |
| Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes A Burger, H Lindsay, A Felker, C Hess, C Anders, E Chiavacci, J Zaugg, ... Development 143 (11), 2025-2037, 2016 | 332 | 2016 |
| Endoribonuclease compositions and methods of use thereof RE Haurwitz, JA Doudna, B Wiedenheft, M Jinek US Patent 9,115,348, 2015 | 326 | 2015 |
