| Autoantibodies against type I IFNs in patients with life-threatening COVID-19 P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ... Science 370 (6515), eabd4585, 2020 | 2746 | 2020 |
| Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ... Science 370 (6515), eabd4570, 2020 | 2352 | 2020 |
| Genomewide association study of severe Covid-19 with respiratory failure Severe Covid-19 GWAS Group New England Journal of Medicine 383 (16), 1522-1534, 2020 | 2032 | 2020 |
| Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis L Liu, S Okada, XF Kong, AY Kreins, S Cypowyj, A Abhyankar, J Toubiana, ... Journal of Experimental Medicine 208 (8), 1635-1648, 2011 | 919 | 2011 |
| Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 843 | 2021 |
| Whole-genome sequencing is more powerful than whole-exome sequencing for detecting exome variants A Belkadi, A Bolze, Y Itan, A Cobat, QB Vincent, A Antipenko, L Shang, ... Proceedings of the National Academy of Sciences 112 (17), 5473-5478, 2015 | 754 | 2015 |
| Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 536 | 2021 |
| Emergence and rapid transmission of SARS-CoV-2 B. 1.1. 7 in the United States NL Washington, K Gangavarapu, M Zeller, A Bolze, ET Cirulli, ... Cell 184 (10), 2587-2594. e7, 2021 | 400 | 2021 |
| X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 385 | 2021 |
| Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission S Karthikeyan, JI Levy, P De Hoff, G Humphrey, A Birmingham, K Jepsen, ... Nature 609 (7925), 101-108, 2022 | 365 | 2022 |
| Inflammatory tumour microenvironment is associated with superior survival in hepatocellular carcinoma patients V Chew, C Tow, M Teo, HL Wong, J Chan, A Gehring, M Loh, A Bolze, ... Journal of hepatology 52 (3), 370-379, 2010 | 311 | 2010 |
| A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection JL Casanova, HC Su, L Abel, A Aiuti, S Almuhsen, AA Arias, P Bastard, ... Cell 181 (6), 1194-1199, 2020 | 274 | 2020 |
| The human gene damage index as a gene-level approach to prioritizing exome variants Y Itan, L Shang, B Boisson, E Patin, A Bolze, M Moncada-Vélez, E Scott, ... Proceedings of the National Academy of Sciences 112 (44), 13615-13620, 2015 | 273 | 2015 |
| Exome and genome sequencing for inborn errors of immunity I Meyts, B Bosch, A Bolze, B Boisson, Y Itan, A Belkadi, V Pedergnana, ... Journal of Allergy and Clinical Immunology 138 (4), 957-969, 2016 | 236 | 2016 |
| Whole-exome-sequencing-based discovery of human FADD deficiency A Bolze, M Byun, D McDonald, NV Morgan, A Abhyankar, L Premkumar, ... The American Journal of Human Genetics 87 (6), 873-881, 2010 | 220 | 2010 |
| Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis Y Ling, S Cypowyj, C Aytekin, M Galicchio, Y Camcioglu, S Nepesov, ... Journal of Experimental Medicine 212 (5), 619-631, 2015 | 212 | 2015 |
| Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia A Bolze, N Mahlaoui, M Byun, B Turner, N Trede, SR Ellis, A Abhyankar, ... Science 340 (6135), 976-978, 2013 | 199 | 2013 |
| Long-term COVID-19 symptoms in a large unselected population ET Cirulli, KM Schiabor Barrett, S Riffle, A Bolze, I Neveux, S Dabe, ... medrxiv, 2020.10. 07.20208702, 2020 | 186 | 2020 |
| Population genetic screening efficiently identifies carriers of autosomal dominant diseases JJ Grzymski, G Elhanan, JA Morales Rosado, E Smith, KA Schlauch, ... Nature medicine 26 (8), 1235-1239, 2020 | 181 | 2020 |
| The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 167 | 2022 |
Jean-Laurent Casanova, MD, PhDProfessor, Rockefeller University; Investigator, Howard Hughes Medical Institute; Head, St. GilesVahvistettu sähköpostiosoite verkkotunnuksessa rockefeller.edu