Mapping intact protein isoforms in discovery mode using top-down proteomics JC Tran, L Zamdborg, DR Ahlf, JE Lee, AD Catherman, KR Durbin, ... Nature 480 (7376), 254-258, 2011 | 780 | 2011 |
Gel-eluted liquid fraction entrapment electrophoresis: an electrophoretic method for broad molecular weight range proteome separation JC Tran, AA Doucette Analytical chemistry 80 (5), 1568-1573, 2008 | 220 | 2008 |
A protease for'middle-down'proteomics C Wu, JC Tran, L Zamdborg, KR Durbin, M Li, DR Ahlf, BP Early, ... Nature methods 9 (8), 822-824, 2012 | 191 | 2012 |
Large-scale top-down proteomics of the human proteome: membrane proteins, mitochondria, and senescence AD Catherman, KR Durbin, DR Ahlf, BP Early, RT Fellers, JC Tran, ... Molecular & Cellular Proteomics 12 (12), 3465-3473, 2013 | 187 | 2013 |
Multiplexed size separation of intact proteins in solution phase for mass spectrometry JC Tran, AA Doucette Analytical chemistry 81 (15), 6201-6209, 2009 | 147 | 2009 |
Analysis of intact protein isoforms by mass spectrometry JD Tipton, JC Tran, AD Catherman, DR Ahlf, KR Durbin, NL Kelleher Journal of Biological Chemistry 286 (29), 25451-25458, 2011 | 135 | 2011 |
The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput JF Kellie, JC Tran, JE Lee, DR Ahlf, HM Thomas, I Ntai, AD Catherman, ... Molecular BioSystems 6 (9), 1532-1539, 2010 | 133 | 2010 |
Size-sorting combined with improved nanocapillary liquid chromatography− mass spectrometry for identification of intact proteins up to 80 kDa A Vellaichamy, JC Tran, AD Catherman, JE Lee, JF Kellie, SMM Sweet, ... Analytical chemistry 82 (4), 1234-1244, 2010 | 117 | 2010 |
A robust two-dimensional separation for top-down tandem mass spectrometry of the low-mass proteome JE Lee, JF Kellie, JC Tran, JD Tipton, AD Catherman, HM Thomas, ... Journal of the American Society for Mass Spectrometry 20, 2183-2191, 2009 | 114 | 2009 |
Optimizing capillary electrophoresis for top‐down proteomics of 30–80 kDa proteins Y Li, PD Compton, JC Tran, I Ntai, NL Kelleher Proteomics 14 (10), 1158-1164, 2014 | 104 | 2014 |
Evaluation of the compact high-field orbitrap for top-down proteomics of human cells DR Ahlf, PD Compton, JC Tran, BP Early, PM Thomas, NL Kelleher Journal of proteome research 11 (8), 4308-4314, 2012 | 102 | 2012 |
Top down proteomics of human membrane proteins from enriched mitochondrial fractions AD Catherman, M Li, JC Tran, KR Durbin, PD Compton, BP Early, ... Analytical chemistry 85 (3), 1880-1888, 2013 | 90 | 2013 |
Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis TP Cleland, ER Schroeter, L Zamdborg, W Zheng, JE Lee, JC Tran, ... Journal of Proteome Research 14 (12), 5252-5262, 2015 | 84 | 2015 |
Robust analysis of the yeast proteome under 50 kDa by molecular-mass-based fractionation and top-down mass spectrometry JF Kellie, AD Catherman, KR Durbin, JC Tran, JD Tipton, JL Norris, ... Analytical chemistry 84 (1), 209-215, 2012 | 66 | 2012 |
Intact mass detection, interpretation, and visualization to automate Top‐Down proteomics on a large scale KR Durbin, JC Tran, L Zamdborg, SMM Sweet, AD Catherman, JE Lee, ... Proteomics 10 (20), 3589-3597, 2010 | 58 | 2010 |
Rapid and effective focusing in a carrier ampholyte solution isoelectric focusing system: a proteome prefractionation tool JC Tran, AA Doucette Journal of proteome research 7 (4), 1761-1766, 2008 | 57 | 2008 |
Intact proteome fractionation strategies compatible with mass spectrometry AA Doucette, JC Tran, MJ Wall, S Fitzsimmons Expert review of proteomics 8 (6), 787-800, 2011 | 55 | 2011 |
High-throughput antibody screening from complex matrices using intact protein electrospray mass spectrometry WS Sawyer, N Srikumar, J Carver, PY Chu, A Shen, A Xu, AJ Williams, ... Proceedings of the National Academy of Sciences 117 (18), 9851-9856, 2020 | 50 | 2020 |
Nano-LC FTICR tandem mass spectrometry for top-down proteomics: routine baseline unit mass resolution of whole cell lysate proteins up to 72 kDa JD Tipton, JC Tran, AD Catherman, DR Ahlf, KR Durbin, JE Lee, JF Kellie, ... Analytical chemistry 84 (5), 2111-2117, 2012 | 48 | 2012 |
Novel interface for high-throughput analysis of biotherapeutics by electrospray mass spectrometry HM Park, VJ Winton, JJ Drader, S Manalili Wheeler, GA Lazar, ... Analytical chemistry 92 (2), 2186-2193, 2019 | 40 | 2019 |