Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13638* | 2021 |
Small heat shock proteins are molecular chaperones. U Jakob, M Gaestel, K Engel, J Buchner Journal of Biological Chemistry 268 (3), 1517-1520, 1993 | 1734 | 1993 |
MAPKAP kinase 2 is essential for LPS-induced TNF-α biosynthesis A Kotlyarov, A Neininger, C Schubert, R Eckert, C Birchmeier, HD Volk, ... Nature cell biology 1 (2), 94-97, 1999 | 1036 | 1999 |
The p38 MAP kinase pathway signals for cytokine‐induced mRNA stabilization via MAP kinase‐activated protein kinase 2 and an AU‐rich region‐targeted mechanism R Winzen, M Kracht, B Ritter, A Wilhelm, CYA Chen, AB Shyu, M Müller, ... The EMBO journal, 1999 | 1008 | 1999 |
Binding of non‐native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation M Ehrnsperger, S Gräber, M Gaestel, J Buchner The EMBO journal, 1997 | 1005 | 1997 |
Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor α by phosphorylation T Rogalla, M Ehrnsperger, X Preville, A Kotlyarov, G Lutsch, C Ducasse, ... Journal of Biological Chemistry 274 (27), 18947-18956, 1999 | 936 | 1999 |
Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins D Stokoe, K Engel, DG Campbell, P Cohen, M Gaestel FEBS letters 313 (3), 307-313, 1992 | 722 | 1992 |
TNF and increased intracellular iron alter macrophage polarization to a detrimental M1 phenotype in the injured spinal cord A Kroner, AD Greenhalgh, JG Zarruk, RP Dos Santos, M Gaestel, S David Neuron 83 (5), 1098-1116, 2014 | 667 | 2014 |
MAPKAP kinases—MKs—two's company, three's a crowd M Gaestel Nature reviews Molecular cell biology 7 (2), 120-130, 2006 | 535 | 2006 |
MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels A Neininger, D Kontoyiannis, A Kotlyarov, R Winzen, R Eckert, HD Volk, ... Journal of Biological Chemistry 277 (5), 3065-3068, 2002 | 510 | 2002 |
Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression … E Hitti, T Iakovleva, M Brook, S Deppenmeier, AD Gruber, D Radzioch, ... Molecular and cellular biology 26 (6), 2399-2407, 2006 | 498 | 2006 |
Targeting innate immunity protein kinase signalling in inflammation M Gaestel, A Kotlyarov, M Kracht Nature Reviews Drug Discovery 8 (6), 480-499, 2009 | 434 | 2009 |
Leptomycin B‐sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation K Engel, A Kotlyarov, M Gaestel The EMBO journal, 1998 | 373 | 1998 |
Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-γ uses a different signaling pathway P Kovarik, D Stoiber, PA Eyers, R Menghini, A Neininger, M Gaestel, ... Proceedings of the National Academy of Sciences 96 (24), 13956-13961, 1999 | 357 | 1999 |
Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor–induced Crohn's-like inflammatory bowel disease D Kontoyiannis, G Boulougouris, M Manoloukos, M Armaka, M Apostolaki, ... The Journal of experimental medicine 196 (12), 1563-1574, 2002 | 345 | 2002 |
Interleukin‐10 targets p38 MAPK to modulate ARE‐dependent TNF mRNA translation and limit intestinal pathology D Kontoyiannis, A Kotlyarov, E Carballo, L Alexopoulou, PJ Blackshear, ... The EMBO journal, 2001 | 325 | 2001 |
Distinct cellular functions of MK2 A Kotlyarov, Y Yannoni, S Fritz, K Laaß, JB Telliez, D Pitman, LL Lin, ... Molecular and cellular biology 22 (13), 4827-4835, 2002 | 311 | 2002 |
Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP‐K2 and its interaction with cytokine mRNAs S Rousseau, N Morrice, M Peggie, DG Campbell, M Gaestel, P Cohen The EMBO journal, 2002 | 282 | 2002 |
p38 mitogen activated protein kinase regulates endothelial VCAM-1 expression at the post-transcriptional level A Pietersma, BC Tilly, M Gaestel, N de Jong, JC Lee, JF Koster, W Sluiter Biochemical and biophysical research communications 230 (1), 44-48, 1997 | 279 | 1997 |
NAMPT is essential for the G-CSF–induced myeloid differentiation via a NAD+–sirtuin-1–dependent pathway J Skokowa, D Lan, BK Thakur, F Wang, K Gupta, G Cario, AM Brechlin, ... Nature medicine 15 (2), 151-158, 2009 | 263 | 2009 |