| PF-06463922, an ALK/ROS1 inhibitor, overcomes resistance to first and second generation ALK inhibitors in preclinical models HY Zou, L Friboulet, DP Kodack, LD Engstrom, Q Li, M West, RW Tang, ... Cancer Cell 28 (1), 70-81, 2015 | 503 | 2015 |
| CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells J Kim, Z Hu, L Cai, K Li, E Choi, B Faubert, D Bezwada, ... Nature 546 (7656), 168-172, 2017 | 291 | 2017 |
| Isotope tracing of human clear cell renal cell carcinomas demonstrates suppressed glucose oxidation in vivo KD Courtney, D Bezwada, T Mashimo, K Pichumani, V Vemireddy, ... Cell metabolism 28 (5), 793-800. e2, 2018 | 254 | 2018 |
| Fatty acid synthesis is required for breast cancer brain metastasis GB Ferraro, A Ali, A Luengo, DP Kodack, A Deik, KL Abbott, D Bezwada, ... Nature cancer 2 (4), 414-428, 2021 | 241 | 2021 |
| The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation DP Kodack, V Askoxylakis, GB Ferraro, Q Sheng, M Badeaux, S Goel, ... Science translational medicine 9 (391), eaal4682, 2017 | 111 | 2017 |
| Preclinical efficacy of ado-trastuzumab emtansine in the brain microenvironment V Askoxylakis, GB Ferraro, DP Kodack, M Badeaux, RC Shankaraiah, ... Journal of the National Cancer Institute 108 (2), djv313, 2016 | 89 | 2016 |
| Mitochondrial NADP+ is essential for proline biosynthesis during cell growth DH Tran, R Kesavan, H Rion, MH Soflaee, A Solmonson, D Bezwada, ... Nature metabolism 3 (4), 571-585, 2021 | 82 | 2021 |
| Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells AB Aurora, V Khivansara, A Leach, JG Gill, M Martin-Sandoval, C Yang, ... Proceedings of the National Academy of Sciences 119 (6), e2120617119, 2022 | 62 | 2022 |
| TRPML1 promotes protein homeostasis in melanoma cells by negatively regulating MAPK and mTORC1 signaling SY Kasitinon, U Eskiocak, M Martin, D Bezwada, V Khivansara, ... Cell reports 28 (9), 2293-2305. e9, 2019 | 58 | 2019 |
| Adipocytes reprogram cancer cell metabolism by diverting glucose towards glycerol-3-phosphate thereby promoting metastasis A Mukherjee, D Bezwada, F Greco, M Zandbergen, T Shen, CY Chiang, ... Nature Metabolism, 1-15, 2023 | 25 | 2023 |
| De novo and salvage purine synthesis pathways across tissues and tumors DH Tran, D Kim, R Kesavan, H Brown, T Dey, MH Soflaee, HS Vu, ... Cell 187 (14), 3602-3618. e20, 2024 | 23 | 2024 |
| Mitochondrial complex I promotes kidney cancer metastasis D Bezwada, L Perelli, NP Lesner, L Cai, B Brooks, Z Wu, HS Vu, V Sondhi, ... Nature 633 (8031), 923-931, 2024 | 20 | 2024 |
| Mitochondrial metabolism in primary and metastatic human kidney cancers D Bezwada, NP Lesner, B Brooks, HS Vu, Z Wu, L Cai, S Kasitinon, ... BioRxiv, 2023 | 18 | 2023 |
| Electron transport chain inhibition increases cellular dependence on purine transport and salvage Z Wu, D Bezwada, F Cai, RC Harris, B Ko, V Sondhi, C Pan, HS Vu, ... Cell metabolism 36 (7), 1504-1520. e9, 2024 | 14 | 2024 |
| Metabolic inflexibility promotes mitochondrial health during liver regeneration X Wang, CJ Menezes, Y Jia, Y Xiao, SSK Venigalla, F Cai, MH Hsieh, ... Science 384 (6701), eadj4301, 2024 | 8 | 2024 |
| Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples F Cai, D Bezwada, L Cai, R Mahar, Z Wu, MC Chang, P Pachnis, C Yang, ... Cell metabolism 35 (10), 1830-1843. e5, 2023 | 8 | 2023 |
| Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells J Kim, Z Hu, L Cai, K Li, E Choi, B Faubert, D Bezwada, ... Nature 569 (7756), E4-E4, 2019 | 7 | 2019 |
| Reporting on FH-deficient renal cell carcinoma using circulating succinylated metabolites D Bezwada, J Brugarolas The Journal of Clinical Investigation 133 (11), 2023 | 5 | 2023 |
| Glycosaminoglycan-mediated lipoprotein uptake protects cancer cells from ferroptosis D Calhoon, L Sang, D Bezwada, N Kim, A Basu, SC Hsu, A Pimentel, ... bioRxiv, 2024 | 1 | 2024 |
| An allosteric cyclin E-CDK2 site mapped by paralog hopping with covalent probes Y Zhang, Z Liu, M Hirschi, O Brodsky, E Johnson, SJ Won, A Nagata, ... Nature Chemical Biology, 1-12, 2024 | | 2024 |
Ralph DeBerardinisDirector, McDermott Center for Human Growth and Development, UT SouthwesternVahvistettu sähköpostiosoite verkkotunnuksessa utsouthwestern.edu