| p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. X Chen, LJ Ko, L Jayaraman, C Prives Genes & development 10 (19), 2438-2451, 1996 | 1041 | 1996 |
| Effects of p21Cip1/Waf1 at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication AB Niculescu III, X Chen, M Smeets, L Hengst, C Prives, SI Reed Molecular and cellular biology, 1998 | 963 | 1998 |
| Examination of the expanding pathways for the regulation of p21 expression and activity YS Jung, Y Qian, X Chen Cellular signalling 22 (7), 1003-1012, 2010 | 517 | 2010 |
| The Potential Tumor Suppressor p73 Differentially Regulates Cellular p53 Target Genes J Zhu, J Jiang, W Zhou, X Chen Cancer research 58 (22), 5061-5065, 1998 | 448 | 1998 |
| p53 modulation of the DNA damage response ES Helton, X Chen Journal of cellular biochemistry 100 (4), 883-896, 2007 | 433 | 2007 |
| Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes A Willis, EJ Jung, T Wakefield, X Chen Oncogene 23 (13), 2330-2338, 2004 | 431 | 2004 |
| The p53 protein is an unusually shaped tetramer that binds directly to DNA. PN Friedman, X Chen, J Bargonetti, C Prives Proceedings of the National Academy of Sciences 90 (8), 3319-3323, 1993 | 420 | 1993 |
| p63α and ΔNp63α can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes M Dohn, S Zhang, X Chen Oncogene 20 (25), 3193-3205, 2001 | 417 | 2001 |
| A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein. J Bargonetti, JJ Manfredi, X Chen, DR Marshak, C Prives Genes & development 7 (12b), 2565-2574, 1993 | 415 | 1993 |
| The common and distinct target genes of the p53 family transcription factors K Harms, S Nozell, X Chen Cellular and Molecular Life Sciences CMLS 61, 822-842, 2004 | 413 | 2004 |
| Direct, activating interaction between glycogen synthase kinase-3β and p53 after DNA damage P Watcharasit, GN Bijur, JW Zmijewski, L Song, A Zmijewska, X Chen, ... Proceedings of the National Academy of Sciences 99 (12), 7951-7955, 2002 | 363 | 2002 |
| Glycogen synthase kinase-3β (GSK3β) binds to and promotes the actions of p53 P Watcharasit, GN Bijur, L Song, J Zhu, X Chen, RS Jope Journal of Biological Chemistry 278 (49), 48872-48879, 2003 | 322 | 2003 |
| MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53 Z Zhang, H Wang, M Li, S Agrawal, X Chen, R Zhang Journal of Biological Chemistry 279 (16), 16000-16006, 2004 | 302 | 2004 |
| The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis G Liu, X Chen Oncogene 21 (47), 7195-7204, 2002 | 256 | 2002 |
| The p53-estrogen receptor loop in cancer C Berger, Y Qian, X Chen Current molecular medicine 13 (8), 1229-1240, 2013 | 254 | 2013 |
| p53 Is Phosphorylated by CDK7-Cyclin H in a p36MAT1-Dependent Manner LJ Ko, SY Shieh, X Chen, L Jayaraman, K Tamai, Y Taya, C Prives, ... Molecular and cellular biology 17 (12), 7220-7229, 1997 | 250 | 1997 |
| p53, through p21 (WAF1/CIP1), induces cyclin D1 synthesis X Chen, J Bargonetti, C Prives Cancer Research 55 (19), 4257-4263, 1995 | 237 | 1995 |
| Identification of a novel p53 functional domain that is necessary for mediating apoptosis J Zhu, W Zhou, J Jiang, X Chen Journal of Biological Chemistry 273 (21), 13030-13036, 1998 | 233 | 1998 |
| Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53 J Wang, J Shou, X Chen Oncogene 19 (14), 1843-1848, 2000 | 228 | 2000 |
| PRMT5 is required for cell-cycle progression and p53 tumor suppressor function A Scoumanne, J Zhang, X Chen Nucleic acids research 37 (15), 4965-4976, 2009 | 220 | 2009 |
