| Calpains and neuronal damage in the ischemic brain: The swiss knife in synaptic injury M Curcio, IL Salazar, M Mele, LMT Canzoniero, CB Duarte Progress in neurobiology 143, 1-35, 2016 | 103 | 2016 |
| Alterations in GABAA-Receptor Trafficking and Synaptic Dysfunction in Brain Disorders M Mele, RO Costa, CB Duarte Frontiers in cellular neuroscience 13, 77, 2019 | 100 | 2019 |
| BDNF regulates the expression and distribution of vesicular glutamate transporters in cultured hippocampal neurons CV Melo, M Mele, M Curcio, D Comprido, CG Silva, CB Duarte PloS one 8 (1), e53793, 2013 | 81 | 2013 |
| Role of GABAAR trafficking in the plasticity of inhibitory synapses M Mele, G Leal, CB Duarte Journal of neurochemistry 139 (6), 997-1018, 2016 | 71 | 2016 |
| Excitotoxic stimulation downregulates the ubiquitin–proteasome system through activation of NMDA receptors in cultured hippocampal neurons MV Caldeira, M Curcio, G Leal, IL Salazar, M Mele, ARA Santos, CV Melo, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (1), 263-274, 2013 | 63 | 2013 |
| Multiple domains in the C-terminus of NMDA receptor GluN2B subunit contribute to neuronal death following in vitro ischemia MM Vieira, J Schmidt, JS Ferreira, K She, S Oku, M Mele, AE Santos, ... Neurobiology of disease 89, 223-234, 2016 | 56 | 2016 |
| Differential role of the proteasome in the early and late phases of BDNF-induced facilitation of LTP AR Santos, M Mele, SH Vaz, B Kellermayer, M Grimaldi, M Colino-Oliveira, ... Journal of Neuroscience 35 (8), 3319-3329, 2015 | 53 | 2015 |
| GABAA receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia M Mele, L Ribeiro, AR Inácio, T Wieloch, CB Duarte Neurobiology of disease 65, 220-232, 2014 | 52 | 2014 |
| Gephyrin Cleavage in In Vitro Brain Ischemia Decreases GABAA Receptor Clustering and Contributes to Neuronal Death JT Costa, M Mele, MS Baptista, JR Gomes, K Ruscher, RJ Nobre, ... Molecular neurobiology 53, 3513-3527, 2016 | 48 | 2016 |
| BDNF increases synaptic NMDA receptor abundance by enhancing the local translation of Pyk2 in cultured hippocampal neurons P Afonso, P De Luca, RS Carvalho, L Cortes, P Pinheiro, B Oliveiros, ... Science signaling 12 (586), eaav3577, 2019 | 38 | 2019 |
| Synaptogenesis stimulates a proteasome-mediated ribosome reduction in axons RO Costa, H Martins, LF Martins, AW Cwetsch, M Mele, JR Pedro, ... Cell reports 28 (4), 864-876. e6, 2019 | 37 | 2019 |
| The RNA-binding protein hnRNP K mediates the effect of BDNF on dendritic mRNA metabolism and regulates synaptic NMDA receptors in hippocampal neurons G Leal, D Comprido, P de Luca, E Morais, L Rodrigues, M Mele, ... Eneuro 4 (6), 2017 | 36 | 2017 |
| Downregulation of GABAA Receptor Recycling Mediated by HAP1 Contributes to Neuronal Death in In Vitro Brain Ischemia M Mele, MC Aspromonte, CB Duarte Molecular neurobiology 54, 45-57, 2017 | 35 | 2017 |
| Cleavage of the vesicular glutamate transporters under excitotoxic conditions AC Lobo, JR Gomes, T Catarino, M Mele, P Fernandez, AR Inácio, ... Neurobiology of disease 44 (3), 292-303, 2011 | 28 | 2011 |
| Transient incubation of cultured hippocampal neurons in the absence of magnesium induces rhythmic and synchronized epileptiform-like activity M Mele, R Vieira, B Correia, P De Luca, FV Duarte, PS Pinheiro, ... Scientific reports 11 (1), 11374, 2021 | 20 | 2021 |
| Preparation of primary cultures of embryonic rat hippocampal and cerebrocortical neurons IL Salazar, M Mele, MV Caldeira, RO Costa, B Correia, S Frisari, ... Bio-protocol 7 (18), e2551-e2551, 2017 | 19 | 2017 |
| Molecular mechanisms of epilepsy: the role of the chloride transporter KCC2 G Belperio, C Corso, CB Duarte, M Mele Journal of Molecular Neuroscience 72 (7), 1500-1515, 2022 | 5 | 2022 |
| GRASP1 ubiquitination regulates AMPA receptor surface expression and synaptic activity in cultured hippocampal neurons M Mele, P De Luca, AR Santos, M Vieira, IL Salazar, PS Pinheiro, ... The FASEB Journal 35 (8), e21763, 2021 | 3 | 2021 |
| Modulation of GABAA Receptors in Cerebral Ischemia: alterations in receptor trafficking coupled to neuronal death after oxygen/glucose deprivation M Mele PQDT-Global, 2013 | 2 | 2013 |
| Synaptic accumulation of GluN2B-containing NMDA receptors mediates the effects of BDNF-TrkB signalling on synaptic plasticity and in epileptogenesis P De Luca, M Mele, S Tanqueiro, F Napoli, U Butkevičiūtė, AC Souto, ... bioRxiv, 2024.10. 21.618702, 2024 | 1 | 2024 |
