A peptide encoded by a putative lncRNA HOXB-AS3 suppresses colon cancer growth JZ Huang, M Chen, DE Chen, XC Gao, S Zhu, H Huang, M Hu, H Zhu, ... Molecular cell 68 (1), 171-184. e6, 2017 | 648 | 2017 |
MiR-373 drives the epithelial-to-mesenchymal transition and metastasis via the miR-373-TXNIP-HIF1α-TWIST signaling axis in breast cancer D Chen, BL Dang, J Huang, M Chen, D Wu, ML Xu, R Li, GR Yan Oncotarget 6 (32), 32701, 2015 | 118 | 2015 |
ACK1 promotes gastric cancer epithelial–mesenchymal transition and metastasis through AKT–POU2F1–ECD signalling SH Xu, JZ Huang, ML Xu, G Yu, XF Yin, D Chen, GR Yan The Journal of pathology 236 (2), 175-185, 2015 | 83 | 2015 |
USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization C Wu, K Luo, F Zhao, P Yin, Y Song, M Deng, J Huang, Y Chen, L Li, ... Cell Death & Differentiation 25 (10), 1855-1869, 2018 | 80 | 2018 |
Epigenetic silencing of ITGA2 by MiR-373 promotes cell migration in breast cancer W Ding, XL Fan, X Xu, JZ Huang, SH Xu, Q Geng, R Li, D Chen, GR Yan PLoS One 10 (8), e0135128, 2015 | 73 | 2015 |
MET Amplification Attenuates Lung Tumor Response to Immunotherapy by Inhibiting STINGMET Is a Biomarker and Driver for ICB Resistance Y Zhang, Q Yang, X Zeng, M Wang, S Dong, B Yang, X Tu, T Wei, W Xie, ... Cancer discovery 11 (11), 2726-2737, 2021 | 64 | 2021 |
The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair Q Zhou, J Huang, C Zhang, F Zhao, W Kim, X Tu, Y Zhang, S Nowsheen, ... Nature communications 11 (1), 1-13, 2020 | 64 | 2020 |
Down‐regulation of TRPS1 stimulates epithelial–mesenchymal transition and metastasis through repression of FOXA1 JZ Huang, M Chen, M Zeng, SH Xu, FY Zou, D Chen, GR Yan The Journal of pathology 239 (2), 186-196, 2016 | 61 | 2016 |
Tandem deubiquitination and acetylation of SPRTN promotes DNA-protein crosslink repair and protects against aging J Huang, Q Zhou, M Gao, S Nowsheen, F Zhao, W Kim, Q Zhu, Y Kojima, ... Molecular cell 79 (5), 824-835. e5, 2020 | 57 | 2020 |
SARS-CoV-2 non-structural protein 13 (nsp13) hijacks host deubiquitinase USP13 and counteracts host antiviral immune response G Guo, M Gao, X Gao, B Zhu, J Huang, K Luo, Y Zhang, J Sun, M Deng, ... Signal transduction and targeted therapy 6 (1), 1-3, 2021 | 53 | 2021 |
CHK2-FOXK axis promotes transcriptional control of autophagy programs Y Chen, J Wu, G Liang, G Geng, F Zhao, P Yin, S Nowsheen, C Wu, Y Li, ... Science advances 6 (1), eaax5819, 2020 | 53 | 2020 |
USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2 J Wu, Y Chen, G Geng, L Li, P Yin, S Nowsheen, Y Li, C Wu, J Liu, F Zhao, ... Cancer Letters 449, 114-124, 2019 | 51 | 2019 |
Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling G Guo, M Gao, X Gao, B Zhu, J Huang, X Tu, W Kim, F Zhao, Q Zhou, ... Nature communications 12 (1), 1-15, 2021 | 47 | 2021 |
A novel UCHL3 inhibitor, perifosine, enhances PARP inhibitor cytotoxicity through inhibition of homologous recombination-mediated DNA double strand break repair Z Song, X Tu, Q Zhou, J Huang, Y Chen, J Liu, SB Lee, W Kim, ... Cell death & disease 10 (6), 1-9, 2019 | 42 | 2019 |
METTL16 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in pancreatic ductal adenocarcinoma X Zeng, F Zhao, G Cui, Y Zhang, RA Deshpande, Y Chen, M Deng, ... Nature Cancer 3 (9), 1088-1104, 2022 | 40 | 2022 |
The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization Y Yan, Z Xu, J Huang, G Guo, M Gao, W Kim, X Zeng, JA Kloeber, Q Zhu, ... Nucleic acids research 48 (22), 12711-12726, 2020 | 39 | 2020 |
Amplification of ACK1 promotes gastric tumorigenesis via ECD-dependent p53 ubiquitination degradation SH Xu, JZ Huang, M Chen, M Zeng, FY Zou, D Chen, GR Yan Oncotarget 8 (8), 12705, 2017 | 34 | 2017 |
ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection F Zhao, W Kim, H Gao, C Liu, Y Zhang, Y Chen, M Deng, Q Zhou, ... Nature Cell Biology 23 (8), 894-904, 2021 | 33 | 2021 |
POU2F1 over-expression correlates with poor prognoses and promotes cell growth and epithelial-to-mesenchymal transition in hepatocellular carcinoma Y Zhong, H Huang, M Chen, J Huang, Q Wu, GR Yan, D Chen Oncotarget 8 (27), 44082, 2017 | 32 | 2017 |
ECD promotes gastric cancer metastasis by blocking E3 ligase ZFP91-mediated hnRNP F ubiquitination and degradation SH Xu, S Zhu, Y Wang, JZ Huang, M Chen, QX Wu, YT He, D Chen, ... Cell death & disease 9 (5), 1-11, 2018 | 31 | 2018 |