Cancer diagnosis using a liquid biopsy: challenges and expectations F Castro-Giner, S Gkountela, C Donato, I Alborelli, L Quagliata, CKY Ng, ... Diagnostics 8 (2), 31, 2018 | 133 | 2018 |
Cell-free DNA analysis in healthy individuals by next-generation sequencing: a proof of concept and technical validation study I Alborelli, D Generali, P Jermann, MR Cappelletti, G Ferrero, ... Cell death & disease 10 (7), 534, 2019 | 124 | 2019 |
A nanobody-based toolset to investigate the role of protein localization and dispersal in Drosophila S Harmansa, I Alborelli, D Bieli, E Caussinus, M Affolter Elife 6, e22549, 2017 | 123 | 2017 |
The Tumor Profiler Study: integrated, multi-omic, functional tumor profiling for clinical decision support A Irmisch, X Bonilla, S Chevrier, KV Lehmann, F Singer, NC Toussaint, ... Cancer Cell 39 (3), 288-293, 2021 | 116 | 2021 |
Tumor mutational burden assessed by targeted NGS predicts clinical benefit from immune checkpoint inhibitors in non‐small cell lung cancer I Alborelli, K Leonards, SI Rothschild, LP Leuenberger, S Savic Prince, ... The Journal of pathology 250 (1), 19-29, 2020 | 116 | 2020 |
Sox6 enhances erythroid differentiation in human erythroid progenitors C Cantù, R Ierardi, I Alborelli, C Fugazza, L Cassinelli, S Piconese, ... Blood, The Journal of the American Society of Hematology 117 (13), 3669-3679, 2011 | 85 | 2011 |
A variant of a killer cell immunoglobulin-like receptor is associated with resistance to PD-1 blockade in lung cancer MP Trefny, SI Rothschild, F Uhlenbrock, D Rieder, B Kasenda, ... Clinical Cancer Research 25 (10), 3026-3034, 2019 | 43 | 2019 |
A scalable solution for tumor mutational burden from formalin-fixed, paraffin-embedded samples using the Oncomine Tumor Mutation Load Assay R Chaudhary, L Quagliata, JP Martin, I Alborelli, D Cyanam, V Mittal, ... Translational lung cancer research 7 (6), 616, 2018 | 42 | 2018 |
The origin recognition complex interacts with a subset of metabolic genes tightly linked to origins of replication E Shor, CL Warren, J Tietjen, Z Hou, U Müller, I Alborelli, FH Gohard, ... PLoS genetics 5 (12), e1000755, 2009 | 35 | 2009 |
The evolutionarily conserved long non‐coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and … RL Mather, A Parolia, SE Carson, E Venalainen, D Roig‐Carles, M Jaber, ... Molecular oncology 15 (7), 1921-1941, 2021 | 32 | 2021 |
Development and application of functionalized protein binders in multicellular organisms D Bieli, I Alborelli, S Harmansa, S Matsuda, E Caussinus, M Affolter International review of cell and molecular biology 325, 181-213, 2016 | 25 | 2016 |
LncRNA HORAS5 Promotes Taxane Resistance in Castration-Resistant Prostate Cancer via a BCL2A1-Dependent Mechanism P Pucci, E Venalainen, I Alborelli, L Quagliata, C Hawkes, R Mather, ... Epigenomics 12 (13), 1123-1138, 2020 | 23 | 2020 |
Perioperative chemoimmunotherapy with durvalumab for muscle-invasive urothelial carcinoma: primary analysis of the single-arm phase II trial SAKK 06/17 R Cathomas, SI Rothschild, S Hayoz, L Bubendorf, BC Özdemir, B Kiss, ... Journal of Clinical Oncology 41 (33), 5131-5139, 2023 | 22 | 2023 |
A highly conserved SOX6 double binding site mediates SOX6 gene downregulation in erythroid cells C Cantu', V Grande, I Alborelli, L Cassinelli, I Cantu’, MT Colzani, ... Nucleic acids research 39 (2), 486-501, 2011 | 22 | 2011 |
Robust assessment of tumor mutational burden in cytological specimens from lung cancer patients I Alborelli, IB Hench, O Chijioke, SS Prince, L Bubendorf, LP Leuenberger, ... Lung Cancer 149, 84-89, 2020 | 19 | 2020 |
Fibroblast growth factor receptor (FGFR) inhibitor rogaratinib in patients with advanced pretreated squamous-cell non-small cell lung cancer over-expressing FGFR mRNA: The SAKK … A Addeo, SI Rothschild, L Holer, M Schneider, C Waibel, S Haefliger, ... Lung Cancer 172, 154-159, 2022 | 16 | 2022 |
Morphologic and molecular analysis of liver injury after SARS-CoV-2 vaccination reveals distinct characteristics S Uzun, CP Zinner, AC Beenen, I Alborelli, EM Bartoszek, J Yeung, ... Journal of Hepatology 79 (3), 666-676, 2023 | 15 | 2023 |
T cell subtype profiling measures exhaustion and predicts anti-PD-1 response I Schillebeeckx, J Earls, KC Flanagan, J Hiken, A Bode, JR Armstrong, ... Scientific reports 12 (1), 1342, 2022 | 15 | 2022 |
Real-world EGFR testing practices for non-small-cell lung cancer by thoracic pathology laboratories across Europe P Hofman, F Calabrese, I Kern, J Adam, A Alarcão, I Alborelli, NT Anton, ... ESMO open 8 (5), 101628, 2023 | 14 | 2023 |
Cemento-osseous dysplasia is caused by RAS-MAPK activation S Haefliger, D Turek, V Andrei, I Alborelli, B Calgua, B Ameline, D Harder, ... Pathology 55 (3), 324-328, 2023 | 14 | 2023 |