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Tyler S. Harmon
Tyler S. Harmon
Junior Group Leader, Leibniz Institute for Polymer Research
Vahvistettu sähköpostiosoite verkkotunnuksessa ipfdd.de
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Vuosi
Coexisting liquid phases underlie nucleolar subcompartments
M Feric, N Vaidya, TS Harmon, DM Mitrea, L Zhu, TM Richardson, ...
Cell 165 (7), 1686-1697, 2016
18362016
Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins
TS Harmon, AS Holehouse, MK Rosen, RV Pappu
elife 6, e30294, 2017
6242017
Phase separation provides a mechanism to reduce noise in cells
A Klosin, F Oltsch, T Harmon, A Honigmann, F Jülicher, AA Hyman, ...
Science 367 (6476), 464-468, 2020
3102020
Quantitative analysis of multilayer organization of proteins and RNA in nuclear speckles at super resolution
J Fei, M Jadaliha, TS Harmon, ITS Li, B Hua, Q Hao, AS Holehouse, ...
Journal of cell science 130 (24), 4180-4192, 2017
2662017
Injectable tissue integrating networks from recombinant polypeptides with tunable order
S Roberts, TS Harmon, JL Schaal, V Miao, K Li, A Hunt, Y Wen, TG Oas, ...
Nature materials 17 (12), 1154-1163, 2018
1682018
Differential solvation of intrinsically disordered linkers drives the formation of spatially organized droplets in ternary systems of linear multivalent proteins
TS Harmon, AS Holehouse, RV Pappu
New Journal of Physics 20 (4), 045002, 2018
1262018
Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers
AE Posey, KM Ruff, TS Harmon, SL Crick, A Li, MI Diamond, RV Pappu
Journal of Biological Chemistry 293 (10), 3734-3746, 2018
1242018
A multi-step nucleation process determines the kinetics of prion-like domain phase separation
EW Martin, TS Harmon, JB Hopkins, S Chakravarthy, JJ Incicco, P Schuck, ...
Nature Communications 12 (1), 4513, 2021
1052021
CAMELOT: A machine learning approach for coarse-grained simulations of aggregation of block-copolymeric protein sequences
KM Ruff, TS Harmon, RV Pappu
The Journal of chemical physics 143 (24), 2015
882015
Power-law population heterogeneity governs epidemic waves
J Neipel, J Bauermann, S Bo, T Harmon, F Jülicher
PloS one 15 (10), e0239678, 2020
502020
Hamiltonian switch metropolis Monte Carlo simulations for improved conformational sampling of intrinsically disordered regions tethered to ordered domains of proteins
A Mittal, N Lyle, TS Harmon, RV Pappu
Journal of chemical theory and computation 10 (8), 3550-3562, 2014
402014
GADIS: Algorithm for designing sequences to achieve target secondary structure profiles of intrinsically disordered proteins
TS Harmon, MD Crabtree, SL Shammas, AE Posey, J Clarke, RV Pappu
Protein Engineering, Design and Selection 29 (9), 339-346, 2016
292016
To mix, or to demix, that is the question
TS Harmon, AS Holehouse, RV Pappu
Biophysical journal 112 (4), 565-567, 2017
202017
Molecular assembly lines in active droplets
TS Harmon, F Jülicher
Physical review letters 128 (10), 108102, 2022
112022
A model for hysteresis observed in phase transitions of thermally responsive intrinsically disordered protein polymers
TS Harmon, S Roberts, A Chilkoti, RV Pappu
Biophysical Journal 112 (3), 207a, 2017
22017
Disordered Proteins: Connecting Sequences to Emergent Properties
TS Harmon
Washington University in St. Louis, 2017
22017
Charge Patterned Sequences form Helical Structures through Charge Neutralization
TS Harmon, RV Pappu
Biophysical Journal 110 (3), 358a, 2016
22016
Droplet differentiation by a chemical switch
X Chen, R Seyboldt, JU Sommer, F Jülicher, T Harmon
Physical Review Letters 133 (2), 028402, 2024
12024
Transport kinetics across interfaces between coexisting liquid phases
L Hubatsch, S Bo, TS Harmon, AA Hyman, CA Weber, F Julicher
bioRxiv, 2024.12. 20.629798, 2024
12024
Increasing the Accuracy in All-Atom Simulations of Intrinsically Disordered Proteins based on the Absinth Model
MJ Fossat, TS Harmon, AE Posey, JM Choi, RV Pappu
Biophysical Journal 114 (3), 432a, 2018
12018
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Artikkelit 1–20