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A reference map of the human binary protein interactome K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ... Nature 580 (7803), 402-408, 2020 | 1099 | 2020 |
Widespread expansion of protein interaction capabilities by alternative splicing X Yang, J Coulombe-Huntington, S Kang, GM Sheynkman, T Hao, ... Cell 164 (4), 805-817, 2016 | 591 | 2016 |
Network-based prediction of protein interactions IA Kovács, K Luck, K Spirohn, Y Wang, C Pollis, S Schlabach, W Bian, ... Nature communications 10 (1), 1240, 2019 | 493 | 2019 |
Drosophila Ras/MAPK signalling regulates innate immune responses in immune and intestinal stem cells A Ragab, T Buechling, V Gesellchen, K Spirohn, AL Boettcher, M Boutros The EMBO journal 30 (6), 1123-1136, 2011 | 144 | 2011 |
Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor T Buechling, K Bartscherer, B Ohkawara, V Chaudhary, K Spirohn, ... Current Biology 20 (14), 1263-1268, 2010 | 133 | 2010 |
p24 proteins are required for secretion of Wnt ligands T Buechling, V Chaudhary, K Spirohn, M Weiss, M Boutros EMBO reports 12 (12), 1265-1272, 2011 | 115 | 2011 |
Maximizing binary interactome mapping with a minimal number of assays SG Choi, J Olivet, P Cassonnet, PO Vidalain, K Luck, L Lambourne, ... Nature communications 10 (1), 3907, 2019 | 72 | 2019 |
Landscape of protein–protein interactions in Drosophila immune deficiency signaling during bacterial challenge H Fukuyama, Y Verdier, Y Guan, C Makino-Okamura, V Shilova, X Liu, ... Proceedings of the National Academy of Sciences 110 (26), 10717-10722, 2013 | 53 | 2013 |
Cdk12 is a gene-selective RNA polymerase II kinase that regulates a subset of the transcriptome, including Nrf2 target genes X Li, N Chatterjee, K Spirohn, M Boutros, D Bohmann Scientific reports 6 (1), 21455, 2016 | 52 | 2016 |
A proteome-scale map of the SARS-CoV-2–human contactome DK Kim, B Weller, CW Lin, D Sheykhkarimli, JJ Knapp, G Dugied, ... Nature biotechnology 41 (1), 140-149, 2023 | 44 | 2023 |
Keap1-independent regulation of Nrf2 activity by protein acetylation and a BET bromodomain protein N Chatterjee, M Tian, K Spirohn, M Boutros, D Bohmann PLoS genetics 12 (5), e1006072, 2016 | 41 | 2016 |
Discovery of progenitor cell signatures by time-series synexpression analysis during Drosophila embryonic cell immortalization ML Dequéant, D Fagegaltier, Y Hu, K Spirohn, A Simcox, GJ Hannon, ... Proceedings of the National Academy of Sciences 112 (42), 12974-12979, 2015 | 33 | 2015 |
eIF 4A inactivates TORC 1 in response to amino acid starvation FF Tsokanos, MA Albert, C Demetriades, K Spirohn, M Boutros, ... The EMBO journal 35 (10), 1058-1076, 2016 | 32 | 2016 |
Assessment of community efforts to advance network-based prediction of protein–protein interactions XW Wang, L Madeddu, K Spirohn, L Martini, A Fazzone, L Becchetti, ... Nature communications 14 (1), 1582, 2023 | 24 | 2023 |
Next-generation large-scale binary protein interaction network for Drosophila melanogaster HW Tang, K Spirohn, Y Hu, T Hao, IA Kovács, Y Gao, R Binari, ... Nature communications 14 (1), 1-16, 2023 | 21 | 2023 |
A map of binary SARS-CoV-2 protein interactions implicates host immune regulation and ubiquitination DK Kim, B Weller, CW Lin, D Sheykhkarimli, J Knapp, N Kishore, M Sauer, ... | 17 | 2021 |
Functional analysis of the Drosophila embryonic germ cell transcriptome by RNA interference F Jankovics, L Henn, Á Bujna, P Vilmos, K Spirohn, M Boutros, M Erdélyi PloS one 9 (6), e98579, 2014 | 12 | 2014 |
EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling LO Randzavola, PM Mortimer, E Garside, ER Dufficy, A Schejtman, ... Elife 11, e76387, 2022 | 11 | 2022 |
AI-guided pipeline for protein–protein interaction drug discovery identifies a SARS-CoV-2 inhibitor P Trepte, C Secker, J Olivet, J Blavier, S Kostova, SB Maseko, I Minia, ... Molecular Systems Biology 20 (4), 428-457, 2024 | 8 | 2024 |